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Browse our BRAF Proteins (BRAF)

Full name:
V-Raf Murine Sarcoma Viral Oncogene Homolog B1 Proteins (BRAF)
On www.antibodies-online.com are 16 V-Raf Murine Sarcoma Viral Oncogene Homolog B1 (BRAF) Proteins from 3 different suppliers available. Additionally we are shipping BRAF Antibodies (378) and BRAF Kits (5) and many more products for this protein. A total of 420 BRAF products are currently listed.
Synonyms:
9930012E13Rik, AA120551, AA387315, AA473386, B-raf, B-RAF1, Braf, Braf-2, BRAF1, Braf2, C-RMIL, C87398, C230098H17, D6Ertd631e, HYPT11, NS7, RAFB1, RMIL, sierrabraf, Sm-E, SME
list all proteins Gene Name GeneID UniProt
BRAF 109880 P28028
BRAF 6635 P62304
Rat BRAF BRAF 114486  

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BRAF Proteins (BRAF) by Origin

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More Proteins for BRAF Interaction Partners

Xenopus laevis V-Raf Murine Sarcoma Viral Oncogene Homolog B1 (BRAF) interaction partners

  1. BRAF alternative splicing is differentially regulated in vertebrates. Exon 9b is present in all vertebrates, including Xenopus, but exon 8b is present only in eutherians.

Zebrafish V-Raf Murine Sarcoma Viral Oncogene Homolog B1 (BRAF) interaction partners

  1. BRAF alternative splicing is differentially regulated in vertebrates. Exon 9b is present in all vertebrates, including Danio rerio, but exon 8b is present only in eutherians.

  2. BRAF activation is sufficient for f-nevus formation, and is among the primary events in melanoma development.

Chimpanzee V-Raf Murine Sarcoma Viral Oncogene Homolog B1 (BRAF) interaction partners

  1. BRAF alternative splicing is differentially regulated in rodent and primates. Exon 9b is present in vertebrates but exon 8b is present only in eutherians.

Mouse (Murine) V-Raf Murine Sarcoma Viral Oncogene Homolog B1 (BRAF) interaction partners

  1. coexpression of BRAF(V600E) and KRAS(G12D) in early tumorigenesis leads to negative selection due to oncogene (show RAB1A Proteins)-induced senescence

  2. findings suggest that targeting ErbB-3 (show ERBB3 Proteins) receptors could represent an effective therapeutic approach in BRAF-V600E mutant colon cancer

  3. Atg7 (show ATG7 Proteins) Overcomes Senescence and Promotes Growth of BrafV600E-Driven Melanoma

  4. Cotargeting is the treatment for mutant RAF (show RAF1 Proteins)/MEK (show MDK Proteins)/ERK (show EPHB2 Proteins) and NF-kB pathways to treat mutant BRAF melanomas.

  5. The CM cell lines, as well as the tumor xenografts and their metastases, were positive for the melanoma markers HMB-45, S100B (show S100B Proteins), and MART-1. Two cell lines and their corresponding xenografts carried a BRAF mutation, the third showed an NRAS (show NRAS Proteins) mutation.

  6. New BRAF knockin mice provide a pathogenetic mechanism of developmental defects and a therapeutic approach in cardiofaciocutaneous syndrome.

  7. Results demonstrate that BRAF activates Usp5 (show USP5 Proteins) to suppress cell cycle checkpoint control and apoptosis by blocking p53 (show TP53 Proteins) and FAS (show FAS Proteins) induction.

  8. The implantation of genetically defined murine BRAF-mutated thyroid cancer cell lines into syngeneic mice results in rapid and synchronous tumor formation.

  9. early activation of the RAF (show RAF1 Proteins) signaling pathway in the ectoderm has effects on specific steps of epidermal differentiation.

  10. The study characterizes a mouse model of melanogenesis where simultaneous Cdkn2a and Lkb1 (show STK11 Proteins) inactivation in Braf(V600E) melanocytes results in activation of both mTORC1 and mTORC2 (show CRTC2 Proteins)/Akt (show AKT1 Proteins), inducing rapid melanoma formation in mice.

Human V-Raf Murine Sarcoma Viral Oncogene Homolog B1 (BRAF) interaction partners

  1. BRAF mutations in cfDNA are detectable in >75% of late-stage melanoma patients with BRAF mutation-positive tumors.

  2. It was suggested that somatic point mutations in BRAF, CDKN2A and PI3KCA do not participate in the oncogenesis of Medullary thyroid carcinoma

  3. Specific inhibition of BRAF oncogene (show RAB1A Proteins), MEK (show MAP2K1 Proteins) or p38 (show CRK Proteins) signaling was associated with decreases in DIO3 (show DIO3 Proteins) expression in papillary thyroid cancer cells

  4. We demonstrated that the BRAF (V600E) mutation slightly correlated with the clinicopathological characteristics of papillary thyroid cancer in the Han population

  5. BRAF mutations are associated with Papillary Thyroid Cancer.

  6. Levels of BRAF(mutant) and NRAS(mutant) ctDNA were determined using droplet digital PCR (ddPCR) assays. Among patients with samples available prior to treatment initiation ctDNA and LDH levels were elevated in 12/15 (80%) and 6/20 (30%) (p = 0.006) patients respectively

  7. four cases harbored the BRAF-V600E mutation, one case harbored the BRAF-G606R mutation, and three cases harbored deletions in exon 19 of EGFR (show EGFR Proteins)

  8. BRAF mutations are associated with response to therapy in metastatic colorectal cancer.

  9. olfactory neuroepithelial progenitor cells with the genetic heritage of bipolar I disorder were more sensitive to glutamate (show GRIN1 Proteins) induced apoptosis. Under expression of the BRAF gene and protein, which plays a role in regulating the pro-survival MEK (show MAP2K1 Proteins)/ERK (show EPHB2 Proteins) signaling pathway, may contribute to this apoptotic sensitivity.

  10. Data indicate that among classic and follicular variant papillary thyroid carcinomas (PTCs), mutation of proto-oncogene (show RAB1A Proteins) protein B (show LEPREL2 Proteins)-raf (BRAF(V600E)) was significantly associated with the smaller size.

Horse (Equine) V-Raf Murine Sarcoma Viral Oncogene Homolog B1 (BRAF) interaction partners

  1. BRAF alternative splicing is differentially regulated in rodent and primates. Exon 9b is present in vertebrates but exon 8b is present only in eutherians.

BRAF Protein Profile

Protein Summary

This gene encodes a protein belonging to the raf/mil family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance. Mutations in this gene have also been associated with various cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma, non-small cell lung carcinoma, and adenocarcinoma of lung. A pseudogene, which is located on chromosome X, has been identified for this gene.

Alternative names and synonyms associated with BRAF

  • v-raf murine sarcoma viral oncogene homolog B (braf)
  • v-raf murine sarcoma viral oncogene homolog B1 (braf)
  • v-raf murine sarcoma viral oncogene homolog B1 (BRAF)
  • v-raf murine sarcoma viral oncogene homolog B1 (LOC100219601)
  • Braf transforming gene (Braf)
  • Braf transforming gene, related sequence 1 (Braf-rs1)
  • small nuclear ribonucleoprotein polypeptide E (SNRPE)
  • v-raf murine sarcoma viral oncogene homolog B (BRAF)
  • v-raf murine sarcoma viral oncogene homolog B (Braf)
  • 9930012E13Rik protein
  • AA120551 protein
  • AA387315 protein
  • AA473386 protein
  • B-raf protein
  • B-RAF1 protein
  • Braf protein
  • Braf-2 protein
  • BRAF1 protein
  • Braf2 protein
  • C-RMIL protein
  • C87398 protein
  • C230098H17 protein
  • D6Ertd631e protein
  • HYPT11 protein
  • NS7 protein
  • RAFB1 protein
  • RMIL protein
  • sierrabraf protein
  • Sm-E protein
  • SME protein

Protein level used designations for BRAF

B-Raf , serine/threonine protein kinase BRAF , v-raf murine sarcoma viral oncogene homolog B1 , serine/threonine-protein kinase B-raf , serine/threonine-protein kinase B-raf-like , B-Raf proto-oncogene serine/threonine-protein kinase (p94) , proto-oncogene B-Raf , sm protein E , small nuclear ribonucleoprotein E , snRNP-E , 94 kDa B-raf protein , murine sarcoma viral (v-raf) oncogene homolog B1 , B-raf protein , B-Raf proto-oncogene serine/threonine-protein kinase , proto-oncogene c-Rmil , rmil serine/threonine-protein kinase , serine/threonine kinase , serine/threonine-protein kinase Rmil

GENE ID SPECIES
398973 Xenopus laevis
403065 Danio rerio
463781 Pan troglodytes
100219601 Taeniopygia guttata
100442288 Pongo abelii
109880 Mus musculus
110709 Mus musculus
6635 Homo sapiens
673 Homo sapiens
114486 Rattus norvegicus
536051 Bos taurus
475526 Canis lupus familiaris
396239 Gallus gallus
100065760 Equus caballus
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