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anti-Chicken Calnexin antibody for Western Blotting

Recommended Calnexin Antibody (supplied by: Log in to see )

Antigen
Calnexin (CANX) Antibodies
  • 1110069N15Rik
  • AI988026
  • CANX
  • canx
  • CG11958
  • clgn
  • clnx
  • Cnx
  • CNX
  • cnx
  • D11Ertd153e
  • Dmel\CG11958
  • IP90
  • P90
  • PP90
  • wu:fe06b12
  • zgc:63524
Epitope
N-Term
101
25
19
13
12
10
5
4
4
3
3
2
2
2
2
2
1
1
1
1
1
1
1
1
1
Reactivity
Chicken, Cow (Bovine), Dog (Canine), Guinea Pig, Hamster, Human, Monkey, Mouse (Murine), Pig (Porcine), Rabbit, Rat (Rattus), Sheep (Ovine), Xenopus laevis
313
177
171
98
91
85
85
83
83
81
81
80
76
52
37
21
12
9
5
4
4
4
4
4
2
2
1
1
1
Host
Rabbit
222
87
24
Clonality
Polyclonal
Conjugate
This Calnexin antibody is un-conjugated
12
10
10
8
7
6
6
5
5
5
5
5
5
5
5
4
4
4
4
4
4
4
4
4
4
3
3
3
3
3
1
1
1
1
1
1
1
Application
Immunocytochemistry (ICC), Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (IHC), Western Blotting (WB)
308
206
161
144
127
107
84
72
11
9
5
3
3
2
2
1
1
Supplier
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Catalog No. ABIN361839
$ 422.40
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.13398065 ABIN1440007 IF WB Goat IgG C-Term Log in to see Polyclonal 1
0.13398065 ABIN1440005 IF WB Goat IgG C-Term Log in to see Polyclonal
0.0011731816 ABIN361782 ICC FACS IF IP IHC WB Rabbit C-Term Log in to see Polyclonal 7
0.0011731816 ABIN264868 IF IP WB Rabbit IgG Log in to see Polyclonal 10
0.0011731816 ABIN264869 IF IP WB Rabbit IgG Log in to see Polyclonal 10
0.0011731816 ABIN2481630 ICC FACS IF IP IHC WB Atto 390 Rabbit C-Term Log in to see Polyclonal 7
0.0011731816 ABIN2481631 ICC FACS IF IP IHC WB Atto 488 Rabbit C-Term Log in to see Polyclonal 7
0.0011731816 ABIN2481634 ICC FACS IF IP IHC WB Atto 633 Rabbit C-Term Log in to see Polyclonal 7
0.0011731816 ABIN2481635 ICC FACS IF IP IHC WB Atto 655 Rabbit C-Term Log in to see Polyclonal 7
0.0011731816 ABIN2481633 ICC FACS IF IP IHC WB Atto 594 Rabbit C-Term Log in to see Polyclonal 7
0.0011731816 ABIN2481636 ICC FACS IF IP IHC WB Atto 680 Rabbit C-Term Log in to see Polyclonal 7
0.0011731816 ABIN2481637 ICC FACS IF IP IHC WB Atto 700 Rabbit C-Term Log in to see Polyclonal 7
0.0011731816 ABIN2481632 ICC FACS IF IP IHC WB Atto 565 Rabbit C-Term Log in to see Polyclonal 7
0.0011731816 ABIN2481638 ICC FACS IF IP IHC WB Alkaline Phosphatase (AP) Rabbit C-Term Log in to see Polyclonal 7
0.0011731816 ABIN2481640 ICC FACS IF IP IHC WB Biotin Rabbit C-Term Log in to see Polyclonal 7
0.0011731816 ABIN2481641 ICC FACS IF IP IHC WB FITC Rabbit C-Term Log in to see Polyclonal 7
0.0011731816 ABIN2481639 ICC FACS IF IP IHC WB APC Rabbit C-Term Log in to see Polyclonal 7
0.0011731816 ABIN2481642 ICC FACS IF IP IHC WB HRP Rabbit C-Term Log in to see Polyclonal 7
0.0011731816 ABIN2481643 ICC FACS IF IP IHC WB PE-Atto 594 Rabbit C-Term Log in to see Polyclonal 7
0.0011731816 ABIN2481644 ICC FACS IF IP IHC WB PerCP Rabbit C-Term Log in to see Polyclonal 7

Top referenced anti-Calnexin antibody for Western Blotting

Similar anti-Calnexin Antibodies

Application / Reactivity Human Cow (Bovine) Chicken Guinea Pig Mouse (Murine) Pig (Porcine) Rabbit Rat (Rattus) Sheep (Ovine)
Western Blotting (WB) 291 Antibodies 91 Antibodies 84 Antibodies 82 Antibodies 164 Antibodies 86 Antibodies 84 Antibodies 159 Antibodies 82 Antibodies

General

Antigen Calnexin (CANX) Antibodies
Epitope N-Term
(101), (25), (19), (13), (12), (10), (5), (4), (4), (3), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Chicken, Cow (Bovine), Dog (Canine), Guinea Pig, Hamster, Human, Monkey, Mouse (Murine), Pig (Porcine), Rabbit, Rat (Rattus), Sheep (Ovine), Xenopus laevis
(313), (177), (171), (98), (91), (85), (85), (83), (83), (81), (81), (80), (76), (52), (37), (21), (12), (9), (5), (4), (4), (4), (4), (4), (2), (2), (1), (1), (1)
Host Rabbit
(222), (87), (24)
Clonality
Polyclonal
Conjugate This Calnexin antibody is un-conjugated
(12), (10), (10), (8), (7), (6), (6), (5), (5), (5), (5), (5), (5), (5), (5), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (3), (3), (3), (3), (3), (1), (1), (1), (1), (1), (1), (1)
Application Immunocytochemistry (ICC), Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (IHC), Western Blotting (WB)
(308), (206), (161), (144), (127), (107), (84), (72), (11), (9), (5), (3), (3), (2), (2), (1), (1)
Pubmed 10 references available
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Product Details anti-Calnexin Antibody

Target Details Calnexin Application Details Handling References for anti-Calnexin Antibody (ABIN361839) Images
Specificity Detects the N-terminal domain of Calnexin ~90 kDa.
Purification Rabbit Antiserum
Immunogen A 19 residue synthetic peptide based on dog calnexin and the peptide coupled to KLH

Target Details Calnexin

Product Details anti-Calnexin Antibody Application Details Handling References for anti-Calnexin Antibody (ABIN361839) Images back to top
Antigen
Alternative Name Calnexin (CANX Antibody Abstract)
Background Calnexin, an abundant ~90 kDa integral protein of the endoplasmic reticulum, is also referred to as IP90, p88 and p90 (1). It consists of a large 50 kDa N-terminal calcium-binding luminal domain, a single transmembrane helix and a short acidic cytoplasmic tail (2, 3). Unlike its ER counterparts which have a KDEL sequence on their C-terminus to ensure ER retention (4), calnexin has positively charged cytosolic residues that do the same thing (3). Most ER proteins act as molecular chaperones and participate in the proper folding of polypeptides and their assembly into mulit-subunit proteins. Calnexin together with calreticulin, plays a key role in glycoprotein folding and its control within the ER, by interacting with folding intermediates via their mono-glycosylated glycans (5, 6). Calnexin has also been shown to associate with the major histocompatibility complex class I heavy chains, partial complexes of the T cell receptor and B cell membrane immunoglobulin (7).
Cellular Localization: Endoplasmic Reticulum | Endoplasmic Reticulum Membrane | Melanosome
Gene ID 403908
NCBI Accession NP_001003232
UniProt P24643
Pathways MAPK Signaling

Application Details

Product Details anti-Calnexin Antibody Target Details Calnexin Handling References for anti-Calnexin Antibody (ABIN361839) Images back to top
Application Notes Recommended Dilution: WB (1:5000), IHC (1:100), ICC/IF (1:100), IP (1:100), optimal dilutions for assays should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-Calnexin Antibody Target Details Calnexin Application Details References for anti-Calnexin Antibody (ABIN361839) Images back to top
Format Liquid
Buffer Rabbit Antiserum
Storage -20 °C

References for anti-Calnexin Antibody (ABIN361839)

Product Details anti-Calnexin Antibody Target Details Calnexin Application Details Handling Images back to top
Product cited in:

Liu, Milner, Boppart, Ross, Kaufman: "β1D chain increases α7β1 integrin and laminin and protects against sarcolemmal damage in mdx mice." in: Human molecular genetics, Vol. 21, Issue 7, pp. 1592-603, 2012

Background publications

Janiszewski, Lopes, Carmo, Pedro, Brandes, Santos, Laurindo: "Regulation of NAD(P)H oxidase by associated protein disulfide isomerase in vascular smooth muscle cells." in: The Journal of biological chemistry, Vol. 280, Issue 49, pp. 40813-9, 2005

Raggo, Rapin, Stirling, Gobeil, Smith-Windsor, OHare, Misra: "Luman, the cellular counterpart of herpes simplex virus VP16, is processed by regulated intramembrane proteolysis." in: Molecular and cellular biology, Vol. 22, Issue 16, pp. 5639-49, 2002

Schrag, Bergeron, Li, Borisova, Hahn, Thomas, Cygler: "The Structure of calnexin, an ER chaperone involved in quality control of protein folding." in: Molecular cell, Vol. 8, Issue 3, pp. 633-44, 2001

Elagöz, Callejo, Armstrong, Rokeach: "Although calnexin is essential in S. pombe, its highly conserved central domain is dispensable for viability." in: Journal of cell science, Vol. 112 ( Pt 23), pp. 4449-60, 2000

Rubio, Wenthold: "Calnexin and the immunoglobulin binding protein (BiP) coimmunoprecipitate with AMPA receptors." in: Journal of neurochemistry, Vol. 73, Issue 3, pp. 942-8, 1999

Otteken, Moss: "Calreticulin interacts with newly synthesized human immunodeficiency virus type 1 envelope glycoprotein, suggesting a chaperone function similar to that of calnexin." in: The Journal of biological chemistry, Vol. 271, Issue 1, pp. 97-103, 1996

Rajagopalan, Xu, Brenner: "Retention of unassembled components of integral membrane proteins by calnexin." in: Science (New York, N.Y.), Vol. 263, Issue 5145, pp. 387-90, 1994

Tjoelker, Seyfried, Eddy, Byers, Shows, Calderon, Schreiber, Gray: "Human, mouse, and rat calnexin cDNA cloning: identification of potential calcium binding motifs and gene localization to human chromosome 5." in: Biochemistry, Vol. 33, Issue 11, pp. 3229-36, 1994

Galvin, Krishna, Ponchel, Frohlich, Cummings, Carlson, Wands, Isselbacher, Pillai, Ozturk: "The major histocompatibility complex class I antigen-binding protein p88 is the product of the calnexin gene." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 89, Issue 18, pp. 8452-6, 1992

Images

Product Details anti-Calnexin Antibody Target Details Calnexin Application Details Handling References for anti-Calnexin Antibody (ABIN361839) back to top
Supplier Images
Western Blotting (WB) image for anti-Calnexin antibody (CANX) (N-Term) (ABIN361839) Calnexin NT, Hela, Western Blotting.