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anti-Quail Calnexin antibody for Immunohistochemistry

Recommended Calnexin Antibody (supplied by: Log in to see )

Antigen
Calnexin (CANX) Antibodies
  • 1110069N15Rik
  • AI988026
  • CANX
  • canx
  • CG11958
  • clgn
  • clnx
  • Cnx
  • CNX
  • cnx
  • D11Ertd153e
  • Dmel\CG11958
  • IP90
  • P90
  • PP90
  • wu:fe06b12
  • zgc:63524
Epitope
C-Term
100
27
19
13
12
10
5
4
4
3
3
2
2
2
2
2
1
1
1
1
1
1
1
1
1
Reactivity
Chicken, Cow (Bovine), Dog (Canine), Fruit Fly (Drosophila melanogaster), Guinea Pig, Hamster, Human, Monkey, Mouse (Murine), Pig (Porcine), Quail, Rabbit, Rat (Rattus), Sheep (Ovine), Xenopus laevis
315
179
172
98
91
86
85
83
83
81
81
80
76
51
36
21
12
9
5
4
4
4
4
4
2
2
1
1
1
Host
Rabbit
222
88
25
Clonality
Polyclonal
Conjugate
This Calnexin antibody is un-conjugated
12
10
10
8
7
6
6
5
5
5
5
5
5
5
5
4
4
4
4
4
4
4
4
4
4
3
3
3
3
3
1
1
1
1
1
1
1
Application
Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (IHC), Western Blotting (WB)
310
208
162
145
129
108
83
73
11
9
6
3
3
2
2
1
1
Supplier
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Catalog No. ABIN361782
$ 228.80
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0011340706 ABIN2481630 ICC FACS IF IP IHC WB Atto 390 Rabbit C-Term Log in to see Polyclonal 7
0.0011340706 ABIN2481631 ICC FACS IF IP IHC WB Atto 488 Rabbit C-Term Log in to see Polyclonal 7
0.0011340706 ABIN2481634 ICC FACS IF IP IHC WB Atto 633 Rabbit C-Term Log in to see Polyclonal 7
0.0011340706 ABIN2481635 ICC FACS IF IP IHC WB Atto 655 Rabbit C-Term Log in to see Polyclonal 7
0.0011340706 ABIN2481633 ICC FACS IF IP IHC WB Atto 594 Rabbit C-Term Log in to see Polyclonal 7
0.0011340706 ABIN2481636 ICC FACS IF IP IHC WB Atto 680 Rabbit C-Term Log in to see Polyclonal 7
0.0011340706 ABIN2481637 ICC FACS IF IP IHC WB Atto 700 Rabbit C-Term Log in to see Polyclonal 7
0.0011340706 ABIN2481632 ICC FACS IF IP IHC WB Atto 565 Rabbit C-Term Log in to see Polyclonal 7
0.0011340706 ABIN2481638 ICC FACS IF IP IHC WB Alkaline Phosphatase (AP) Rabbit C-Term Log in to see Polyclonal 7
0.0011340706 ABIN2481640 ICC FACS IF IP IHC WB Biotin Rabbit C-Term Log in to see Polyclonal 7
0.0011340706 ABIN2481641 ICC FACS IF IP IHC WB FITC Rabbit C-Term Log in to see Polyclonal 7
0.0011340706 ABIN2481639 ICC FACS IF IP IHC WB APC Rabbit C-Term Log in to see Polyclonal 7
0.0011340706 ABIN2481642 ICC FACS IF IP IHC WB HRP Rabbit C-Term Log in to see Polyclonal 7
0.0011340706 ABIN2481643 ICC FACS IF IP IHC WB PE-Atto 594 Rabbit C-Term Log in to see Polyclonal 7
0.0011340706 ABIN2481644 ICC FACS IF IP IHC WB PerCP Rabbit C-Term Log in to see Polyclonal 7
0.0011340706 ABIN2481645 ICC FACS IF IP IHC WB PE Rabbit C-Term Log in to see Polyclonal 7
0.0011340706 ABIN2481646 ICC FACS IF IP IHC WB Streptavidin Rabbit C-Term Log in to see Polyclonal 7
0.0011340706 ABIN361827 ICC IF IHC WB Rabbit C-Term Log in to see Polyclonal 11
0.0011340706 ABIN2486646 ICC IF IHC WB Atto 390 Rabbit C-Term Log in to see Polyclonal 7
0.0011340706 ABIN2486648 ICC IF IHC WB Atto 565 Rabbit C-Term Log in to see Polyclonal 7

Top referenced anti-Calnexin antibody for Immunohistochemistry

Similar anti-Calnexin Antibodies

Application / Reactivity Human Cow (Bovine) Chicken Fruit Fly (Drosophila melanogaster) Guinea Pig Mouse (Murine) Pig (Porcine) Rabbit
Western Blotting (WB) 292 Antibodies 90 Antibodies 84 Antibodies 52 Antibodies 82 Antibodies 165 Antibodies 86 Antibodies 84 Antibodies

General

Antigen Calnexin (CANX) Antibodies
Epitope C-Term
(100), (27), (19), (13), (12), (10), (5), (4), (4), (3), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Chicken, Cow (Bovine), Dog (Canine), Fruit Fly (Drosophila melanogaster), Guinea Pig, Hamster, Human, Monkey, Mouse (Murine), Pig (Porcine), Quail, Rabbit, Rat (Rattus), Sheep (Ovine), Xenopus laevis
(315), (179), (172), (98), (91), (86), (85), (83), (83), (81), (81), (80), (76), (51), (36), (21), (12), (9), (5), (4), (4), (4), (4), (4), (2), (2), (1), (1), (1)
Host Rabbit
(222), (88), (25)
Clonality
Polyclonal
Conjugate This Calnexin antibody is un-conjugated
(12), (10), (10), (8), (7), (6), (6), (5), (5), (5), (5), (5), (5), (5), (5), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (3), (3), (3), (3), (3), (1), (1), (1), (1), (1), (1), (1)
Application Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (IHC), Western Blotting (WB)
(310), (208), (162), (145), (129), (108), (83), (73), (11), (9), (6), (3), (3), (2), (2), (1), (1)
Pubmed 7 references available
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Product Details anti-Calnexin Antibody

Target Details Calnexin Application Details Handling References for anti-Calnexin Antibody (ABIN361782) Images
Specificity Detects the C-terminal domain of Calnexin ~90 kDa. Weak detection in Chicken, Drosophila, and Xenopus tissues.
Purification Protein A Purified
Immunogen Dog Calnexin C-terminal synthetic peptide conjugated to KLH. Identical to human, mouse and rat calnexin sequences over these residues.

Target Details Calnexin

Product Details anti-Calnexin Antibody Application Details Handling References for anti-Calnexin Antibody (ABIN361782) Images back to top
Antigen
Alternative Name Calnexin (CANX Antibody Abstract)
Background Calnexin, an abundant ~90 kDa integral protein of the endoplasmic reticulum, is also referred to as IP90, p88 and p90 (1). It consists of a large 50 kDa N-terminal calcium-binding luminal domain, a single transmembrane helix and a short acidic cytoplasmic tail (2, 3). Unlike its ER counterparts which have a KDEL sequence on their C-terminus to ensure ER retention (4), calnexin has positively charged cytosolic residues that do the same thing (3). Most ER proteins act as molecular chaperones and participate in the proper folding of polypeptides and their assembly into multi-subunit proteins. Calnexin together with calreticulin, plays a key role in glycoprotein folding and its control within the ER, by interacting with folding intermediates via their mono-glycosylated glycans (5, 6). Calnexin has also been shown to associate with the major histocompatibility complex class I heavy chains, partial complexes of the T cell receptor and B cell membrane immunoglobulin (7).
Cellular Localization: Endoplasmic Reticulum | Endoplasmic Reticulum Membrane | Melanosome
Gene ID 403908
NCBI Accession NP_001003232
UniProt P24643
Pathways MAPK Signaling

Application Details

Product Details anti-Calnexin Antibody Target Details Calnexin Handling References for anti-Calnexin Antibody (ABIN361782) Images back to top
Application Notes Recommended Dilution: WB (1:2000), ICC/IF (1:100), IHC (1:100), optimal dilutions for assays should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-Calnexin Antibody Target Details Calnexin Application Details References for anti-Calnexin Antibody (ABIN361782) Images back to top
Format Liquid
Concentration 1 mg/mL
Buffer PBS pH 7.2, 50 % glycerol, 0.09 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C

References for anti-Calnexin Antibody (ABIN361782)

Product Details anti-Calnexin Antibody Target Details Calnexin Application Details Handling Images back to top
Background publications

Janiszewski, Lopes, Carmo, Pedro, Brandes, Santos, Laurindo: "Regulation of NAD(P)H oxidase by associated protein disulfide isomerase in vascular smooth muscle cells." in: The Journal of biological chemistry, Vol. 280, Issue 49, pp. 40813-9, 2005

Schrag, Bergeron, Li, Borisova, Hahn, Thomas, Cygler: "The Structure of calnexin, an ER chaperone involved in quality control of protein folding." in: Molecular cell, Vol. 8, Issue 3, pp. 633-44, 2001

Elagöz, Callejo, Armstrong, Rokeach: "Although calnexin is essential in S. pombe, its highly conserved central domain is dispensable for viability." in: Journal of cell science, Vol. 112 ( Pt 23), pp. 4449-60, 2000

Otteken, Moss: "Calreticulin interacts with newly synthesized human immunodeficiency virus type 1 envelope glycoprotein, suggesting a chaperone function similar to that of calnexin." in: The Journal of biological chemistry, Vol. 271, Issue 1, pp. 97-103, 1996

Rajagopalan, Xu, Brenner: "Retention of unassembled components of integral membrane proteins by calnexin." in: Science (New York, N.Y.), Vol. 263, Issue 5145, pp. 387-90, 1994

Tjoelker, Seyfried, Eddy, Byers, Shows, Calderon, Schreiber, Gray: "Human, mouse, and rat calnexin cDNA cloning: identification of potential calcium binding motifs and gene localization to human chromosome 5." in: Biochemistry, Vol. 33, Issue 11, pp. 3229-36, 1994

Galvin, Krishna, Ponchel, Frohlich, Cummings, Carlson, Wands, Isselbacher, Pillai, Ozturk: "The major histocompatibility complex class I antigen-binding protein p88 is the product of the calnexin gene." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 89, Issue 18, pp. 8452-6, 1992

Images

Product Details anti-Calnexin Antibody Target Details Calnexin Application Details Handling References for anti-Calnexin Antibody (ABIN361782) back to top
Supplier Images
 image for anti-Calnexin antibody (CANX) (C-Term) (ABIN361782) Calnexin CT, rat tissue mix.