anti-Human Caspase 9 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended Caspase 9 Antibody (supplied by: Log in to see )

Antigen
Caspase 9, Apoptosis-Related Cysteine Peptidase (CASP9) Antibodies
  • CASP9
  • AI115399
  • APAF-3
  • AW493809
  • CASP-9
  • Caspase-9
  • ICE-LAP6
  • Mch6
  • Apaf3
  • Casp-9-CTD
  • Casp9_v1
  • Ice-Lap6
  • APAF3
  • MCH6
  • PPP1R56
  • caspase 9
  • caspase 9, apoptosis-related cysteine peptidase
  • caspase-9-like
  • CASP9
  • LOC100101592
  • Casp9
  • LOC100518913
Epitope
AA 20-69
42
23
21
18
17
16
15
15
15
12
11
11
10
9
7
6
6
6
5
5
5
5
4
4
4
4
4
4
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Dog (Canine), Human, Mouse (Murine), Rat (Rattus)
432
149
139
22
12
10
6
6
5
3
2
1
Host
Rabbit
426
47
1
Clonality
Polyclonal
Conjugate
This Caspase 9 antibody is un-conjugated
11
10
7
4
4
4
4
4
4
4
4
4
4
4
4
3
3
Application
Flow Cytometry (FACS), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
408
150
137
91
75
74
52
33
22
15
13
10
6
2
2
2
1
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Catalog No. ABIN724160
$ 307.45
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
11.569707 ABIN153015 ICC IF IHC IHC (p) WB Mouse IgG1 kappa Log in to see LAP6 96-2-22 5
11.569707 ABIN4288194 FACS IHC IHC (fro) IHC (p) IP Rabbit Log in to see Polyclonal 15
11.569707 ABIN756922 IF (p) IHC (p) WB Rabbit IgG AA 180-220, pSer196 Log in to see Polyclonal
11.569707 ABIN498253 IF IHC (p) WB Rabbit Log in to see Polyclonal
11.569707 ABIN498192 IF IHC (p) WB Rabbit Log in to see Polyclonal
11.569707 ABIN615299 EIA IF IHC (p) WB Rabbit AA 299-318, N-Term Log in to see Polyclonal
11.569707 ABIN462358 IHC (p) IP WB Mouse IgG1 Log in to see 2-22
11.569707 ABIN4288196 ICC IF IHC IHC (p) WB Rabbit Log in to see Polyclonal
11.569707 ABIN4288203 ICC IF IHC IHC (p) WB Rabbit IgG Log in to see Polyclonal
1 ABIN683863 IF (p) IHC (p) WB Rabbit IgG pThr125 Log in to see Polyclonal 1
1 ABIN4288190 IHC IHC (fro) IHC (p) IP SimWes WB Rabbit Proform Log in to see Polyclonal 6
1 ABIN724175 IF (p) IHC (p) WB Rabbit IgG AA 280-330 Log in to see Polyclonal 3
1 ABIN389526 IHC (p) WB Rabbit Ig pSer196 Log in to see Polyclonal 4
1 ABIN392509 IF IHC (p) WB Rabbit Ig AA 183-211, Center Log in to see Polyclonal 3
1 ABIN5552123 EIA IHC (p) WB Rabbit Ig Fraction pSer196 Log in to see Polyclonal
1 ABIN1881137 FACS IHC (p) WB Rabbit Ser196 Log in to see Polyclonal 5
1 ABIN127028 IF IHC (p) IP WB Rabbit Asp330, N-Term Log in to see Polyclonal
1 ABIN5611417 IHC (p) WB Rabbit IgG AA 345-359, AA 366-383 Log in to see Polyclonal
1 ABIN3044458 IHC (p) WB Rabbit IgG AA 183-198, Middle Region Log in to see Polyclonal 15
1 ABIN4288198 IHC IHC (p) IP WB Rabbit Proform Log in to see Polyclonal 2

General

Antigen Caspase 9, Apoptosis-Related Cysteine Peptidase (CASP9) Antibodies
Epitope AA 20-69
(42), (23), (21), (18), (17), (16), (15), (15), (15), (12), (11), (11), (10), (9), (7), (6), (6), (6), (5), (5), (5), (5), (4), (4), (4), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Dog (Canine), Human, Mouse (Murine), Rat (Rattus)
(432), (149), (139), (22), (12), (10), (6), (6), (5), (3), (2), (1)
Host Rabbit
(426), (47), (1)
Clonality
Polyclonal
Conjugate This Caspase 9 antibody is un-conjugated
(11), (10), (7), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (3), (3)
Application Flow Cytometry (FACS), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(408), (150), (137), (91), (75), (74), (52), (33), (22), (15), (13), (10), (6), (2), (2), (2), (1)
Pubmed 6 references available
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Product Details anti-Caspase 9 Antibody

Target Details Caspase 9 Application Details Handling ProductDetails: References for anti-Caspase 9 antibody (ABIN724160) Images
Purification Purified by Protein A.
Immunogen KLH conjugated synthetic peptide derived from human Caspase 9 subunit p35
Isotype IgG

Target Details Caspase 9

Product Details anti-Caspase 9 Antibody Application Details Handling ProductDetails: References for anti-Caspase 9 antibody (ABIN724160) Images back to top
Antigen
Alternative Name Caspase 9 (CASP9 Antibody Abstract)
Background

Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP). Isoform 2 lacks activity is an dominant-negative inhibitor of caspase-9.

Subcellular location: Cytoplasm

Synonyms: MCH6, APAF3, APAF-3, PPP1R56, ICE-LAP6, Caspase-9, CASP-9, Apoptotic protease Mch-6, Apoptotic protease-activating factor 3, ICE-like apoptotic protease 6, CASP9

Gene ID 842
UniProt P55211
Research Area Cancer, Apoptosis/Necrosis
Pathways MAPK Signaling, RTK Signaling, Apoptosis, Caspase Cascade in Apoptosis, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Endopeptidase Activity

Application Details

Product Details anti-Caspase 9 Antibody Target Details Caspase 9 Handling ProductDetails: References for anti-Caspase 9 antibody (ABIN724160) Images back to top
Application Notes WB 1:100-1000
FCM 1:20-100
IHC-P 1:100-500
IF(IHC-P) 1:50-200
Restrictions For Research Use only

Handling

Product Details anti-Caspase 9 Antibody Target Details Caspase 9 Application Details ProductDetails: References for anti-Caspase 9 antibody (ABIN724160) Images back to top
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C
Expiry Date 12 months

ProductDetails: References for anti-Caspase 9 antibody (ABIN724160)

Product Details anti-Caspase 9 Antibody Target Details Caspase 9 Application Details Handling Images back to top
Product cited in:

Wang, Xuan, Cui, Wang, Chen, Wei, Zhao: "Ibutilide treatment protects against ER stress induced apoptosis by regulating calumenin expression in tunicamycin treated cardiomyocytes." in: PLoS ONE, Vol. 12, Issue 4, pp. e0173469, 2017 Method employed by authors: Western Blotting (WB) (Sample species: Rat (Rattus)).

Wang, Wang, Huang, Yang, Zhao, Wei, Zhao: "Ibutilide protects against cardiomyocytes injury via inhibiting endoplasmic reticulum and mitochondrial stress pathways." in: Heart and vessels, 2016

Pan, Yang, Wang, Wang, Wang, Zhou, Yin, Zhang, Zhao: "C-Abl tyrosine kinase mediates neurotoxic prion peptide-induced neuronal apoptosis via regulating mitochondrial homeostasis." in: Molecular neurobiology, Vol. 49, Issue 2, pp. 1102-16, 2014

Zhao, Xu, Yun, Zhao, Li, Gong, Yuan, Yan, Zhang, Ding, Wang, Zhang, Dong, Xiu, Yang, Liu, Xue, Li: "Chronic obstructive sleep apnea causes atrial remodeling in canines: mechanisms and implications." in: Basic research in cardiology, Vol. 109, Issue 5, pp. 427, 2014

Wang, Lu, Dai, Zhang, Wang, Wei: "Esculetin, a coumarin derivative, exerts in vitro and in vivo antiproliferative activity against hepatocellular carcinoma by initiating a mitochondrial-dependent apoptosis pathway." in: Brazilian journal of medical and biological research = Revista brasileira de pesquisas médicas e biológicas / Sociedade Brasileira de Biofísica ... [et al.], 2014 Method employed by authors: Western Blotting (WB) (Sample species: Mouse (Murine)).

Wang, Han, Zhou, Wu, Wang, Jia, Lv, Cheng, Pan, Liu, Zhou, Sun: "Inhibition of hydrogen sulfide synthesis provides protection for severe acute pancreatitis rats via apoptosis pathway." in: Apoptosis : an international journal on programmed cell death, Vol. 18, Issue 1, pp. 28-42, 2013

Images

Product Details anti-Caspase 9 Antibody Target Details Caspase 9 Application Details Handling ProductDetails: References for anti-Caspase 9 antibody (ABIN724160) back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-Caspase 9, Apoptosis-Related Cysteine Peptidase (CASP9) (AA 20-69) antibody (ABIN724160) Formalin-fixed and paraffin embedded human colon carcinoma labeled with Anti-Caspase-...
Immunohistochemistry (IHC) image for anti-Caspase 9, Apoptosis-Related Cysteine Peptidase (CASP9) (AA 20-69) antibody (ABIN724160) Formalin-fixed and paraffin embedded rat brain labeled with Anti-Caspase-9 Polyclonal...
Western Blotting (WB) image for anti-Caspase 9, Apoptosis-Related Cysteine Peptidase (CASP9) (AA 20-69) antibody (ABIN724160) Raji lysates probed with Rabbit Anti-Caspase 9 Polyclonal Antibody, Unconjugated at ...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Caspase 9, Apoptosis-Related Cysteine Peptidase (CASP9) (AA 20-69) antibody (ABIN724160) Formalin-fixed and paraffin embedded human colon carcinoma labeled with Anti-Caspase-...
Flow Cytometry (FACS) image for anti-Caspase 9, Apoptosis-Related Cysteine Peptidase (CASP9) (AA 20-69) antibody (ABIN724160) RSC96 probed with Caspase 9 Polyclonal Antibody, Unconjugated at 1:100 for 30 minute...