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anti-Rat (Rattus) Cortactin antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended Cortactin Antibody (supplied by: Log in to see )

Antigen
Cortactin (CTTN) Antibodies
  • Cttn
  • CTTN
  • cttn
  • ems1
  • CG3637
  • Dmel\CG3637
  • cortactin
  • 1110020L01Rik
  • Ems1
  • CTTN1
  • P85.25
  • EMS1
  • Cttnb
  • cortactin
  • src substrate cortactin
  • Src substrate cortactin
  • CG3637 gene product from transcript CG3637-RD
  • CTTN
  • Cttn
  • cttn
  • CpipJ_CPIJ006351
  • Bm1_57220
  • LOC100533277
  • Cortactin
Epitope
pTyr421
30
28
16
16
15
13
9
7
7
6
4
3
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
191
117
66
8
7
5
3
2
2
1
1
1
1
1
1
Host
Rabbit
176
29
17
Clonality
Polyclonal
Conjugate
This Cortactin antibody is un-conjugated
4
4
4
4
4
4
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
186
99
91
28
20
12
11
3
3
2
2
1
1
Supplier
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Available images

Catalog No. ABIN498755
$ 390.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
12.096792 ABIN498635 IHC (p) WB Rabbit Log in to see Polyclonal
12.096792 ABIN4300127 ICC IF IHC IHC (p) WB Rabbit IgG Center Log in to see Polyclonal
12.096792 ABIN4300126 ICC IF IHC IHC (p) WB Rabbit IgG N-Term Log in to see Polyclonal
12.096792 ABIN4300120 IHC IHC (p) WB Rabbit pTyr421 Log in to see Polyclonal
12.096792 ABIN4300118 IHC IHC (p) WB Rabbit Log in to see Polyclonal
1 ABIN2854674 ICC IF IHC (p) WB Rabbit IgG N-Term Log in to see Polyclonal
1 ABIN447054 ICC IF IHC (p) IHC WB Rabbit Log in to see Polyclonal
1 ABIN1733371 IHC (p) WB Rabbit IgG Log in to see Polyclonal
1 ABIN4300123 ELISA IHC IHC (p) WB Rabbit C-Term, pTyr466 Log in to see Polyclonal
1 ABIN680293 IF (p) IHC (p) WB Rabbit IgG Log in to see Polyclonal
1 ABIN2718800 EIA IHC (p) WB Rabbit IgG Log in to see Polyclonal

Similar anti-Cortactin Antibodies

Application / Reactivity Mouse (Murine) Human Rat (Rattus)
Western Blotting (WB) 94 Antibodies 165 Antibodies 62 Antibodies
Proximity Ligation Assay (PLA) 1 Antibodies
Immunoprecipitation (IP) 7 Antibodies 4 Antibodies 1 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 22 Antibodies 18 Antibodies 12 Antibodies
Immunohistochemistry (IHC) 86 Antibodies 57 Antibodies 30 Antibodies
Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) 2 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 1 Antibodies 1 Antibodies 1 Antibodies
Immunofluorescence (IF) 19 Antibodies 14 Antibodies

General

Antigen Cortactin (CTTN) Antibodies
Epitope pTyr421
(30), (28), (16), (16), (15), (13), (9), (7), (7), (6), (4), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(191), (117), (66), (8), (7), (5), (3), (2), (2), (1), (1), (1), (1), (1), (1)
Host Rabbit
(176), (29), (17)
Clonality
Polyclonal
Conjugate This Cortactin antibody is un-conjugated
(4), (4), (4), (4), (4), (4)
Application Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(186), (99), (91), (28), (20), (12), (11), (3), (3), (2), (2), (1), (1)
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Product Details anti-Cortactin Antibody

Target Details Cortactin Application Details Handling Images
Specificity This antibody detects endogenous levels of Cortactin protein only when phosphorylated at Tyr421.
Cross-Reactivity (Details) Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.
Purification Affinity Chromatography using epitope-specific immunogen.

Target Details Cortactin

Product Details anti-Cortactin Antibody Application Details Handling Images back to top
Antigen
Alternative Name Cortactin (CTTN Antibody Abstract)
Background Cortactin (also designated Ems-1) is a filamentous Actin (FActin) binding protein. It has also been shown to be a substrate for Src p60. Cortactin contains tandem 37 amino acid repeats at the amino-terminus and an SH3 domain at the carboxy-terminus. The tandem repeats appear to be necessary for F-Actin binding. Tyrosine phosphorylation of Cortactin by Src p60 results in diminished F-Actin binding to Cortactin and reduced F-Actin cross-linking activity. Cortactin has also been shown to be phosphorylated in response to FGF-1. Cortactin exhibits abundant expression in megakaryocytes and platelets, and it may play a role in the maturation of megakaryocytes.Synonyms: Amplaxin, CTTN, EMS1, Oncogene EMS1
Molecular Weight approx. 85.0 kDa
Gene ID 2017
NCBI Accession NP_005222
UniProt Q14247
Research Area Cancer, Cell Cycle, Cytoskeleton, Microfilaments
Pathways MAPK Signaling

Application Details

Product Details anti-Cortactin Antibody Target Details Cortactin Handling Images back to top
Application Notes Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-Cortactin Antibody Target Details Cortactin Application Details Images back to top
Concentration 1.0 mg/mL
Buffer Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Images

Product Details anti-Cortactin Antibody Target Details Cortactin Application Details Handling back to top
Supplier Images
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Cortactin antibody (CTTN) (pTyr421) (ABIN498755) Immunohistochemistry analysis of Cortactin antibody in paraffin-embedded human...
Western Blotting (WB) image for anti-Cortactin antibody (CTTN) (pTyr421) (ABIN498755) Western blot analysis of Cortactin antibody in extracts from 3T3 H2O2 cells