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anti-Mouse (Murine) EIF4EBP1 antibody for Enzyme Immunoassay

Recommended EIF4EBP1 Antibody (supplied by: Log in to see )

Antigen
Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1) Antibodies
  • 4e-bp
  • 4E-BP
  • 4e-bp1
  • 4E-BP1
  • 4ebp
  • 4eBP
  • 4EBP
  • 4EBP1
  • 43-BP
  • 153432_at
  • AA959816
  • anon-WO0172774.158
  • BcDNA.HL08053
  • BcDNA:HL08053
  • BP-1
  • CG8846
  • CT8705
  • d4e-bp
  • d4E-BP
  • d4E-BP1
  • d4EBP
  • d4eBP
  • Dm 4E-BP
  • Dmel\\CG8846
  • dthor
  • eIF4E-BP
  • EIF4EBP1
  • fc04h09
  • l(2)06270
  • l(2)k07736
  • l(2)k13517
  • PHAS-I
  • Phas1
  • pp20
  • thor
  • Thor/EIF4EBP
  • wu:fc04h09
  • zgc:64137
Epitope
C-Term
59
30
29
22
20
18
17
14
14
13
13
13
12
12
10
10
10
8
8
6
5
5
5
4
4
3
3
3
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine)
409
232
185
10
8
5
2
2
1
1
1
Host
Rabbit
377
71
9
Clonality
Polyclonal
Conjugate
This EIF4EBP1 antibody is un-conjugated
19
16
11
10
7
7
5
5
5
5
5
5
5
5
5
1
1
Application
Enzyme Immunoassay (EIA), Immunofluorescence (IF), Western Blotting (WB)
288
193
170
62
56
23
21
18
12
7
5
4
3
3
3
1
Supplier
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Catalog No. ABIN499179
$ 401.50
Plus shipping costs $45.00

Top referenced anti-EIF4EBP1 antibody for Enzyme Immunoassay

Similar anti-EIF4EBP1 Antibodies

Application / Reactivity Mouse (Murine) Human
ELISA 55 Antibodies 151 Antibodies
Enzyme Immunoassay (EIA) 1 Antibodies 4 Antibodies
Flow Cytometry (FACS) 12 Antibodies
Gel Shift (GS) 2 Antibodies
Immunochromatography (IC) 2 Antibodies
Immunocytochemistry (ICC) 8 Antibodies
Immunofluorescence (IF) 15 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 56 Antibodies
Immunohistochemistry (IHC) 100 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 1 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 39 Antibodies
Immunoprecipitation (IP) 3 Antibodies
Intracellular Staining (ICS) 4 Antibodies
Western Blotting (WB) 137 Antibodies
Dot Blot (DB) 18 Antibodies

General

Antigen Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1) Antibodies
Epitope C-Term
(59), (30), (29), (22), (20), (18), (17), (14), (14), (13), (13), (13), (12), (12), (10), (10), (10), (8), (8), (6), (5), (5), (5), (4), (4), (3), (3), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine)
(409), (232), (185), (10), (8), (5), (2), (2), (1), (1), (1)
Host Rabbit
(377), (71), (9)
Clonality
Polyclonal
Conjugate This EIF4EBP1 antibody is un-conjugated
(19), (16), (11), (10), (7), (7), (5), (5), (5), (5), (5), (5), (5), (5), (5), (1), (1)
Application Enzyme Immunoassay (EIA), Immunofluorescence (IF), Western Blotting (WB)
(288), (193), (170), (62), (56), (23), (21), (18), (12), (7), (5), (4), (3), (3), (3), (1)
Pubmed 2 references available
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Product Details anti-EIF4EBP1 Antibody

Target Details EIF4EBP1 Application Details Handling References for anti-EIF4EBP1 Antibody (ABIN499179) Images
Specificity 4E-BP1 antibody was raised against a 14 amino acid peptide from near the carboxy-terminus of human 4E-BP1.
Purification Affinity chromatography purified via peptide column
Immunogen A 14 amino acid peptide from near the carboxy-terminus of Human 4E-BP1
Isotype IgG

Target Details EIF4EBP1

Product Details anti-EIF4EBP1 Antibody Application Details Handling References for anti-EIF4EBP1 Antibody (ABIN499179) Images back to top
Antigen
Alternative Name EIF4EBP1 / 4E-BP1 (EIF4EBP1 Antibody Abstract)
Background The translation of mRNA in eukaryotic cells is regulated by the presence of amino acids through multiple mechanisms (reviewed in 1). One such mechanism involves the evolutionarily conserved serine/threonine kinase TOR (Target of rapamycin, also known as mTOR), which regulates cell growth and cell cycle through its ability to integrate signals from nutrient levels and growth factors (reviewed in 2). One downstream target of TOR is the eukaryotic initiation factor 4E binding protein 1 (4E-BP1) whose phosphorylation prevents its association with eIF4E, preferentially stimulating translation of mRNAs containing long, highly structured 5'-UTRs (1). Rapamycin inhibits TOR resulting in reduced cell growth and reduced rates of cell cycle and cell proliferation (reviewed in 3), at least in part by inhibiting the activity of TOR towards 4E-BP1.Synonyms: Eukaryotic translation initiation factor 4E-binding protein 1, PHAS-1, PHAS-I, PHAS1, Phosphorylated heat- and acid-stable protein regulated by insulin 1, eIF4E-binding protein 1
Gene ID 1978
NCBI Accession NP_004086
UniProt Q13541
Pathways MAPK Signaling, PI3K-Akt Signaling, RTK Signaling, AMPK Signaling

Application Details

Product Details anti-EIF4EBP1 Antibody Target Details EIF4EBP1 Handling References for anti-EIF4EBP1 Antibody (ABIN499179) Images back to top
Application Notes ELISA. Western Blot: 4E-BP1 antibody can be used for the detection of 4E-BP1 at 2.5 - 5 μg/mL. Immunofluorescence.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-EIF4EBP1 Antibody Target Details EIF4EBP1 Application Details References for anti-EIF4EBP1 Antibody (ABIN499179) Images back to top
Buffer PBS containing 0.02 % Sodium Azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment Store the antibody undiluted at 2-8 °C.

References for anti-EIF4EBP1 Antibody (ABIN499179)

Product Details anti-EIF4EBP1 Antibody Target Details EIF4EBP1 Application Details Handling Images back to top
Background publications

Shamji, Nghiem, Schreiber: "Integration of growth factor and nutrient signaling: implications for cancer biology." in: Molecular cell, Vol. 12, Issue 2, pp. 271-80, 2003

Shah, Anthony, Kimball, Jefferson: "4E-BP1 and S6K1: translational integration sites for nutritional and hormonal information in muscle." in: American journal of physiology. Endocrinology and metabolism, Vol. 279, Issue 4, pp. E715-29, 2000

Images

Product Details anti-EIF4EBP1 Antibody Target Details EIF4EBP1 Application Details Handling References for anti-EIF4EBP1 Antibody (ABIN499179) back to top
Supplier Images
Immunofluorescence (IF) image for anti-EIF4EBP1 antibody (Eukaryotic Translation Initiation Factor 4E Binding Protein 1) (C-Term) (ABIN499179) Immunocytochemistry of AP30001PU-N 4E-BP1 antibody in 3T3 cells with 4E-BP1 antibody ...
Western Blotting (WB) image for anti-EIF4EBP1 antibody (Eukaryotic Translation Initiation Factor 4E Binding Protein 1) (C-Term) (ABIN499179) Western blot analysis of AP30001PU-N 4E-BP1 antibody in 3T3 cell lysate with 4E-BP1 a...