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anti-Mouse (Murine) ERK2 antibody for Intracellular Staining

Recommended ERK2 Antibody (supplied by: Log in to see )

Antigen
Mitogen-Activated Protein Kinase 1 (MAPK1) Antibodies
  • 9030612K14Rik
  • AA407128
  • ATMPK1
  • ATMPK2
  • AU018647
  • C78273
  • erk
  • ERK
  • ERK2
  • Erk2
  • erk2
  • ert1
  • ERT1
  • F14N23.9
  • F14N23_9
  • mapk
  • mapk1
  • MAPK1
  • mapk1a
  • mapk1b
  • MAPK2
  • mapk2
  • MITOGEN-ACTIVATED PROTEIN KINASE
  • mitogen-activated protein kinase 1
  • MITOGEN-ACTIVATED PROTEIN KINASE HOMOLOG 2
  • mitogen-activated protein kinase homolog 2
  • mpk1
  • p38
  • p40
  • p41
  • p41mapk
  • p42mapk
  • P42MAPK
  • Prkm1
  • prkm1
  • PRKM1
  • PRKM2
  • prkm2
  • T30E16.13
  • T30E16_13
  • Xp42
  • xp42
  • zERK2
Reactivity
Human, Mouse (Murine)
256
77
65
16
14
7
5
3
3
3
2
2
2
1
1
1
1
Host
Mouse
153
106
16
3
1
Clonality
Monoclonal
Conjugate
This ERK2 antibody is conjugated to PE
6
5
5
4
4
4
1
1
1
1
Application
Intracellular Staining (ICS)
241
106
79
49
42
42
16
13
10
7
5
2
1
1
1
1
1
1
Supplier
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Catalog No. ABIN1176892
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Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0008676689 ABIN1176894 ICS Alexa Fluor 488 Mouse IgG1, kappa Log in to see G263-7 4
0.0008676689 ABIN1176893 ICS Alexa Fluor 647 Mouse IgG1, kappa Log in to see G263-7 1

Top referenced anti-ERK2 antibody for Intracellular Staining

Similar anti-ERK2 Antibodies

Application / Reactivity Human Mouse (Murine)
Western Blotting (WB) 222 Antibodies 69 Antibodies
Proximity Ligation Assay (PLA) 2 Antibodies
Luminex Assay (LMNX) 5 Antibodies
Intracellular Staining (ICS) 3 Antibodies 3 Antibodies
Immunostaining (ISt) 1 Antibodies
Immunoprecipitation (IP) 38 Antibodies 17 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 6 Antibodies 42 Antibodies
Immunohistochemistry (IHC) 29 Antibodies 74 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 8 Antibodies 1 Antibodies
Immunofluorescence (IF) 44 Antibodies 10 Antibodies

General

Antigen Mitogen-Activated Protein Kinase 1 (MAPK1) Antibodies
Reactivity Human, Mouse (Murine)
(256), (77), (65), (16), (14), (7), (5), (3), (3), (3), (2), (2), (2), (1), (1), (1), (1)
Host Mouse
(153), (106), (16), (3), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This ERK2 antibody is conjugated to PE
(6), (5), (5), (4), (4), (4), (1), (1), (1), (1)
Application Intracellular Staining (ICS)
(241), (106), (79), (49), (42), (42), (16), (13), (10), (7), (5), (2), (1), (1), (1), (1), (1), (1)
Pubmed 1 reference available
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Product Details anti-ERK2 Antibody

Target Details ERK2 Application Details Handling References for anti-ERK2 Antibody (ABIN1176892) Images
Brand BD Phosflow™
Purification The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
Immunogen Human ERK2 Synthetic Peptide
Clone G263-7
Isotype IgG1, kappa

Target Details ERK2

Product Details anti-ERK2 Antibody Application Details Handling References for anti-ERK2 Antibody (ABIN1176892) Images back to top
Antigen
Alternative Name ERK2 (MAPK1 Antibody Abstract)
Background The members of the Mitogen-Activated Protein Kinase (MAPK) family are components of a key signal transduction cascade that links events at the cell surface to responses in the nucleus. The signaling cascade is found in species as varied as yeast and humans, with many of the proteins being well conserved. In mammals the most widely studied members of the cascade are the Extracellular signal-Regulated Kinases, ERK1 (p44 MAPK) and ERK2 (p42 MAPK). ERK1 and ERK2 share 85% homology and are activated by extracellular signals such as growth factors, hormones, and phorbol esters. Activation occurs through a series of phosphorylations by kinases activating other kinases and eventually leading to phosphorylation of the ERKs. Growth factor stimulation leads to activation of Ras and Raf, leading to phosphorylation of MEK1 (MAPK/ERK kinase) which, in turn, activates the ERKs via dual phosphorylation. Once activated, the ERKs phosphorylate other cytoplasmic signaling molecules (protein kinases and phosphatases), cell-surface receptors, microtubule-associated proteins, and transcription factors in the nucleus. Thus, the active ERK has myriad downstream effectors that implicate it in the control of cell proliferation and differentiation, as well as regulation of the cytoskeleton. Furthermore, studies have shown that elevated ERK activity is associated with some cancers. The G263-7 recognizes ERK2. It does not cross-react with ERK1. Clone G263-7 was originally characterized in human (A431) and mouse (NIH/3T3) cells. A human ERK2 synthetic peptide was used as immunogen.
Research Area Inflammation
Pathways MAPK Signaling, RTK Signaling, Apoptosis, TCR Signaling, Interferon-gamma Pathway, Fc-epsilon Receptor Signaling Pathway

Application Details

Product Details anti-ERK2 Antibody Target Details ERK2 Handling References for anti-ERK2 Antibody (ABIN1176892) Images back to top
Sample Volume 20 μL
Restrictions For Research Use only

Handling

Product Details anti-ERK2 Antibody Target Details ERK2 Application Details References for anti-ERK2 Antibody (ABIN1176892) Images back to top
Format Liquid
Buffer Aqueous buffered solution containing BSA and ≤0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. The antibody was conjugated with R-PE under optimum conditions, and unconjugated antibody and free PE were removed.

References for anti-ERK2 Antibody (ABIN1176892)

Product Details anti-ERK2 Antibody Target Details ERK2 Application Details Handling Images back to top
Product cited in:

Treisman: "Regulation of transcription by MAP kinase cascades." in: Current opinion in cell biology, Vol. 8, Issue 2, pp. 205-15, 1996

Images

Product Details anti-ERK2 Antibody Target Details ERK2 Application Details Handling References for anti-ERK2 Antibody (ABIN1176892) back to top
Supplier Images
Flow Cytometry (FACS) image for anti-ERK2 antibody (Mitogen-Activated Protein Kinase 1)  (PE) (ABIN1176892) anti-Mitogen-Activated Protein Kinase 1 (MAPK1) antibody (PE)