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anti-Pig (Porcine) HSPB1 antibody for Immunohistochemistry

Recommended HSPB1 Antibody (supplied by: Log in to see )

Antigen
Heat Shock 27kDa Protein 1 (HSPB1) Antibodies
  • cb153
  • cb660
  • hsp1
  • hsp25
  • hsp27
  • id:ibd2821
  • sb:cb660
  • zgc:103437
  • HSPB1
  • cmt2f
  • hs.76067
  • hsp28
  • CMT2F
  • HMN2B
  • HS.76067
  • HSP27
  • HSP28
  • Hsp25
  • SRP27
  • Hs.78846
  • LOH11CR1K
  • MKBP
  • Hsp27
  • 27kDa
  • 2810021G24Rik
  • heat shock protein, alpha-crystallin-related, 1
  • heat shock 27kDa protein 1
  • heat shock 27kDa protein 2
  • heat shock protein 1
  • heat shock protein 2
  • heat shock protein 25
  • hspb1
  • HSPB1
  • HSP27
  • HSPB2
  • Hspb1
  • Hspb2
  • HSP25
Reactivity
Human, Monkey, Mouse (Murine), Pig (Porcine), Rat (Rattus)
819
267
257
85
77
71
65
43
31
28
23
22
19
8
4
4
4
2
2
1
1
1
Host
Rabbit
512
335
3
Clonality
Polyclonal
Conjugate
This HSPB1 antibody is un-conjugated
34
33
23
19
13
13
12
12
11
11
9
9
9
8
8
8
8
8
6
5
5
5
5
5
5
5
5
5
5
3
3
3
3
3
3
3
3
3
3
2
2
Application
Immunoprecipitation (IP), Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
700
332
277
236
220
216
169
124
59
40
18
15
8
6
4
2
2
2
Options
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Catalog No. ABIN2440490
$ 240.26
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN2440476 IEM ICC IF IP IHC WB Rabbit Log in to see Polyclonal

Similar anti-HSPB1 Antibodies

Application / Reactivity Human Mouse (Murine) Pig (Porcine) Rat (Rattus) Monkey
Cytometry by Time of Flight (CyTOF) 8 Antibodies 8 Antibodies 2 Antibodies 8 Antibodies
Simple Western (SimWes) 4 Antibodies
Western Blotting (WB) 677 Antibodies 207 Antibodies 210 Antibodies 20 Antibodies 21 Antibodies
Radioimmunoassay (RIA) 2 Antibodies
Proximity Ligation Assay (PLA) 2 Antibodies
Immunoprecipitation (IP) 160 Antibodies 60 Antibodies 9 Antibodies 62 Antibodies 2 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 217 Antibodies 4 Antibodies

General

Antigen Heat Shock 27kDa Protein 1 (HSPB1) Antibodies
Reactivity Human, Monkey, Mouse (Murine), Pig (Porcine), Rat (Rattus)
(819), (267), (257), (85), (77), (71), (65), (43), (31), (28), (23), (22), (19), (8), (4), (4), (4), (2), (2), (1), (1), (1)
Host Rabbit
(512), (335), (3)
Clonality
Polyclonal
Conjugate This HSPB1 antibody is un-conjugated
(34), (33), (23), (19), (13), (13), (12), (12), (11), (11), (9), (9), (9), (8), (8), (8), (8), (8), (6), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2)
Application Immunoprecipitation (IP), Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
(700), (332), (277), (236), (220), (216), (169), (124), (59), (40), (18), (15), (8), (6), (4), (2), (2), (2)
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Product Details anti-HSPB1 Antibody

Target Details HSPB1 Application Details Handling Images
Specificity Recognizes human, mouse, rat, monkey, and pig HSP27. Detects a band of ~27 kDa by Western blot.
Characteristics Hsp27 is one of the most common members of the highly conserved and ubiquitously expressed family of small heat shock proteins (sHsp), which also includes alphaB-crystallin. It is characterized by a conserved C-terminal alpha-crystallin domain consisting of two anti-parallel beta-sheets that promote oligomer formation required for its primary chaperone function as inhibitor of irreversible protein aggregation. Hsp27 oligomerization is modulated by post-translational phosphorylation of Hsp27 at three serine residues, Ser15, Ser78, and Ser82, by a variety of protein kinases including MAPKAPK-3, PKAc-alpha, p70 S6K, PKD I, and PKC-delta. Hsp27 has been shown to inhibit actin polymerization by binding of unphosphorylated Hsp27 monomers to actin intermediate filaments. Anti-apoptotic functions of Hsp27 have also been identified through interactions with DAXX7, activation of Akt, and inhibition of apoptosome formation. Evidence suggests altered expression of Hsp27 is implicated in the pathogenesis of breast, ovarian, and prostate cancer
Purification Protein A affinity purified.
Immunogen Recombinant human Hsp27.

Target Details HSPB1

Product Details anti-HSPB1 Antibody Application Details Handling Images back to top
Antigen
Alternative Name HSP27 (HSPB1 Antibody Abstract)
Gene ID 3315
Research Area Heat Shock Proteins
Pathways MAPK Signaling

Application Details

Product Details anti-HSPB1 Antibody Target Details HSPB1 Handling Images back to top
Restrictions For Research Use only

Handling

Product Details anti-HSPB1 Antibody Target Details HSPB1 Application Details Images back to top
Format Liquid
Buffer In PBS containing 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Storage -20 °C
Storage Comment Long Term Storage :-20 °C