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JAK1 Proteins

(Janus Kinase 1 (JAK1))
Janus kinase 1 (JAK1), is a member of a new class of protein-tyrosine kinases (PTK) characterized by the presence of a second phosphotransferase-related domain immediately N-terminal to the PTK domain. The second phosphotransferase domain bears all the hallmarks of a protein kinase, although its structure differs significantly from that of the PTK and threonine/serine kinase family members. JAK1 is a large, widely expressed membrane-associated phosphoprotein. JAK1 is involved in the interferon-alpha/beta and -gamma signal transduction pathways. The reciprocal interdependence between JAK1 and TYK2 activities in the interferon-alpha pathway, and between JAK1 and JAK2 in the interferon-gamma pathway, may reflect a requirement for these kinases in the correct assembly of interferon receptor complexes. These kinases couple cytokine ligand binding to tyrosine phosphorylation of various known signaling proteins and of a unique family of transcription factors termed the signal transducers and activators of transcription, or STATs. [provided by RefSeq, Jul 2008].
JAK1 Protein (AA 850-1154) (GST tag) JAK1 Protein (AA 850-1154) (GST tag) JAK1 Protein (AA 850-1154) (GST tag) (ABIN5570138)

JAK1 Origin: Human Host: Insect cells (Sf21) Recombinant SDS, Func Active

JAK1 Protein (AA 221-320) (GST tag) JAK1 Protein (AA 221-320) (GST tag) JAK1 Protein (AA 221-320) (GST tag) (ABIN1308275)

JAK1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA

JAK1 Protein (AA 1-1154) (His tag) JAK1 Protein (AA 1-1154) (His tag) JAK1 Protein (AA 1-1154) (His tag) (ABIN3093202)

Crystallography grade JAK1 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys

JAK1 Proteins by Grade

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JAK1 Proteins by Origin

Find JAK1 Proteins for a variety of species such as anti-Human JAK1, anti-Mouse JAK1, anti-Rat JAK1. The species listed below are among those available. Click on a link to go to the corresponding products.

JAK1 Proteins by Source

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JAK1 Proteins by Protein Type

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JAK1 Proteins by Application

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JAK1 Proteins by Biological Activity

Find JAK1 Proteins with a specific Biological Activity. The Biological Activity listed below are among those available. Click on a link to go to the corresponding products.

Popular JAK1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Insect cells (Sf21)
Validations
  • (2)
Cat. No. ABIN5570138
Quantity 5 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1308275
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3093202
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3134423
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
Cat. No. ABIN5508974
Quantity 10 μg
Datasheet Datasheet
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7413241
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7396508
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7405699
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN7013428
Quantity 50 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3010290
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2734726
Quantity 20 μg
Datasheet Datasheet
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN6380809
Quantity 1 mg
Datasheet Datasheet

Aliases for JAK1 Proteins

Janus kinase 1 (JAK1) Proteins
Janus kinase 1 (Jak1) Proteins
Janus kinase 1 (jak1) Proteins
tyrosine-protein kinase JAK1 (LOC100286690) Proteins
AA960307 Proteins
C130039L05Rik Proteins
jak1 Proteins
JAK1A Proteins
JAK1B Proteins
JTK3 Proteins
wu:fb93e10 Proteins
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