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|Application / Reactivity||Human||Mouse (Murine)||Rat (Rattus)||Dog (Canine)||Cow (Bovine)|
|Western Blotting (WB)||276 Antibodies||89 Antibodies||73 Antibodies||5 Antibodies||5 Antibodies|
|RNA Interference (RNAi)||1 Antibodies|
|Proximity Ligation Assay (PLA)||3 Antibodies|
|Intracellular Staining (ICS)||2 Antibodies||2 Antibodies|
|Immunostaining (ISt)||1 Antibodies|
|Immunoprecipitation (IP)||47 Antibodies||5 Antibodies||6 Antibodies|
|Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))||62 Antibodies||21 Antibodies||18 Antibodies||3 Antibodies||3 Antibodies|
|Immunohistochemistry (IHC)||88 Antibodies||30 Antibodies|
|Antigen||Mitogen-Activated Protein Kinase 8 (MAPK8) Antibodies|
|Epitope||AA 170-210, pThr183, pTyr185 Alternatives|
|Reactivity||Cow (Bovine), Dog (Canine), Human, Mouse (Murine), Rat (Rattus) Alternatives|
|Conjugate||This JNK antibody is un-conjugated Alternatives|
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
|4 references available|
|Supplier||Log in to see|
Product Details anti-JNK AntibodyTarget Details JNK Application Details Handling References for anti-JNK Antibody (ABIN732368) Images
|Purification||Purified by Protein A.|
|Immunogen||KLH conjugated synthetic phosphopeptide derived from human JNK1 around the phosphorylation site of Thr183/Tyr185|
Target Details JNKProduct Details anti-JNK Antibody Application Details Handling References for anti-JNK Antibody (ABIN732368) Images back to top
|Alternative Name||JNK1 , 2 , 3 (MAPK8 Antibody Abstract)|
JNK1 isoforms display different binding patterns: beta-1 preferentially binds to c-Jun, whereas alpha-1, alpha-2, and beta-2 have a similar low level of binding to both c-Jun or ATF2. However, there is no correlation between binding and phosphorylation, which is achieved at about the same efficiency by all isoforms.
Subcellular location: Cytoplasm, Nucleus
Synonyms: JNK, JNK1, PRKM8, SAPK1, JNK-46, JNK1A2, SAPK1c, JNK21B1/2, Mitogen-activated protein kinase 8, MAP kinase 8, MAPK 8, Stress-activated protein kinase 1c, Stress-activated protein kinase JNK1, c-Jun N-terminal kinase 1, MAPK8
|Pathways||MAPK Signaling, WNT Signaling, TCR Signaling, TLR Signaling, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway|
Application DetailsProduct Details anti-JNK Antibody Target Details JNK Handling References for anti-JNK Antibody (ABIN732368) Images back to top
|Application Notes||WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)|
|Restrictions||For Research Use only|
HandlingProduct Details anti-JNK Antibody Target Details JNK Application Details References for anti-JNK Antibody (ABIN732368) Images back to top
|Buffer||Aqueous buffered solution containing 100 μg/mL BSA, 50 % glycerol and 0.09 % sodium azide.|
|Precaution of Use||This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Storage Comment||Store at -20°C|
|Expiry Date||12 months|
References for anti-JNK Antibody (ABIN732368)Product Details anti-JNK Antibody Target Details JNK Application Details Handling Images back to top
|Product cited in:||
Król, Mucha, Majchrzak et al.: "Macrophages mediate a switch between canonical and non-canonical Wnt pathways in canine mammary tumors." in: PLoS ONE, Vol. 9, Issue 1, pp. e83995, 2014 (PubMed).
Song, Liu, Li et al.: "Protective effects of lipoic acid and mesna on cyclophosphamide-induced haemorrhagic cystitis in mice." in: Cell biochemistry and function, 2013 (PubMed).
Rosenzweig, Ou, Quinn: "P38 mitogen-activated protein kinase promotes dedifferentiation of primary articular chondrocytes in monolayer culture." in: Journal of cellular and molecular medicine, Vol. 17, Issue 4, pp. 508-17, 2013 (PubMed).
Rosenzweig, Djap, Ou et al.: "Mechanical injury of bovine cartilage explants induces depth-dependent, transient changes in MAP kinase activity associated with apoptosis." in: Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society, Vol. 20, Issue 12, pp. 1591-602, 2012 (PubMed).
ImagesProduct Details anti-JNK Antibody Target Details JNK Application Details Handling References for anti-JNK Antibody (ABIN732368) back to top