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Browse our MAP2K2 (MAP2K2) ELISA Kits

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Mitogen-Activated Protein Kinase Kinase 2 ELISA Kits (MAP2K2)
On www.antibodies-online.com are 10 Mitogen-Activated Protein Kinase Kinase 2 (MAP2K2) ELISA Kits from 4 different suppliers available. Additionally we are shipping MAP2K2 Antibodies (238) and MAP2K2 Proteins (18) and many more products for this protein. A total of 283 MAP2K2 products are currently listed.
Synonyms:
AA589381, ATMKK2, CFC4, F27B13.50, F27B13_50, MAP KINASE KINASE 1, MAP kinase kinase 2, MAPKK2, MEK2, MK1, MK2, MKK2, PRKMK2
list all ELISA KIts Gene Name GeneID UniProt
MAP2K2 58960 P36506
MAP2K2 5605 P36507
MAP2K2 26396 Q63932

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More ELISA Kits for MAP2K2 Interaction Partners

Human Mitogen-Activated Protein Kinase Kinase 2 (MAP2K2) interaction partners

  1. at clinically relevant concentrations, cDDP binds to and inhibits MEK1 (show MAP2K1 ELISA Kits)/2 and both the binding and inhibitory activity are related to its interaction with Cu bound to MEK1 (show MAP2K1 ELISA Kits)/2

  2. Endocytosis separates EGF (show EGF ELISA Kits) receptors from endogenous fluorescently labeled HRas (show HRAS ELISA Kits) and diminishes receptor signaling to MAP kinases in endosomes.

  3. MEK1 (show MAP2K1 ELISA Kits) levels are upregulated at transcriptional level whereas MEK2 levels are downregulated at posttranslational level.

  4. MEK1/2 inhibitor trametinib showed similar PFS and a response rate as docetaxel in patients with previously treated KRAS-mutant-positive non-small cell lung carcinoma.

  5. We report on a fourth familial case with transmission of CFC (show PTPN11 ELISA Kits) syndrome from father to son due to a novel heterozygous sequence change c.376A>G (p.N126D) in exon 3 of MEK2 gene.

  6. MK2 (show KCNA2 ELISA Kits) attenuates dendritic cell-mediated Th1 (show TH1L ELISA Kits) differentiation and autoimmune encephalomyelitis.

  7. We documented three novel mutations in the BRAF (show BRAF ELISA Kits) gene in cardio-facio-cutaneous syndrome patients and correlated clinical findings with causative mutations in the BRAF (show BRAF ELISA Kits) or MEK1 (show MAP2K1 ELISA Kits)/MEK2 genes

  8. CCR7 (show CCR7 ELISA Kits) can also promote survival of mDCs through a novel MEK1 (show MAP2K1 ELISA Kits)/2-ERK1/2 (show MAPK1/3 ELISA Kits)-AMPK (show PRKAA1 ELISA Kits) signaling axis.

  9. Our cohort of seven individuals with MEK2 deletions has overlapping features associated with RASopathies.

  10. Both ACE (show ACE ELISA Kits) inhibition and MEK1 (show MAP2K1 ELISA Kits)/2 inhibition have beneficial effects on left ventricular function in Lmna (show LMNA ELISA Kits)(H222P/H222P) mice and both drugs together have a synergistic benefit when initiated after the onset of left ventricular dysfunction.

Mouse (Murine) Mitogen-Activated Protein Kinase Kinase 2 (MAP2K2) interaction partners

  1. MK2 (show KCNA2 ELISA Kits)/3 cascade plays a strategic role in controlling synaptic plasticity and cognition.

  2. MK2 (show KCNA2 ELISA Kits) attenuates dendritic cell-mediated Th1 (show HAND1 ELISA Kits) differentiation and autoimmune encephalomyelitis.

  3. analysis of p38 (show CRK ELISA Kits)-MK2 (show KCNA2 ELISA Kits)-activated Rsk (show RPS6KA1 ELISA Kits) signaling in toll (show TLR4 ELISA Kits)-like receptor-stimulated dendritic cells

  4. both MEK1 (show MAP2K1 ELISA Kits) and MEK2 have crucial roles in the integration of mesenchymal and epithelial signals essential for the development of the entire respiratory tract

  5. MK2 (show KCNA2 ELISA Kits) is responsible for resistance of p53 (show TP53 ELISA Kits)-deficient tumors to cisplatin

  6. MK2 (show KCNA2 ELISA Kits) plays a critical role in the development of apoptosis.

  7. rapamycin treatment led to an increased MKP1 (show DUSP1 ELISA Kits) expression in BMDM from WT but failed to do so in BMDMs lacking the AKT1 (show AKT1 ELISA Kits) isoform or MEK1 (show MAP2K1 ELISA Kits) and MEK2.

  8. review focuses on the role of the MEK1 (show MAP2K1 ELISA Kits) and MEK2 kinases in the development of extraembryonic tissues and in the formation of the placenta

  9. AT(2)R-mediated eNOS (show NOS3 ELISA Kits) NO production and vasorelaxation through a MEK (show MDK ELISA Kits) pathway are enhanced in aortas from db/db (show LEPR ELISA Kits) mice.

  10. Crucial role of the ERK/MAPK (show MAPK1 ELISA Kits) cascade in the formation of extraembryonic structures.

Arabidopsis thaliana Mitogen-Activated Protein Kinase Kinase 2 (MAP2K2) interaction partners

  1. the AtMKK2-AtMPK10 (show MAPK10 ELISA Kits) MAPK (show MAPK1 ELISA Kits) module regulates leaf venation complexity by altering polar auxin transport efficiency

  2. Treatment of Arabidopsis with a membrane rigidifier, DMSO, causes MPK4 (show MAPK4 ELISA Kits) activation concomitantly with MEKK1 (show MAP3K1 ELISA Kits) and MKK2 phosphorylation.

  3. Ca(2 (show CA2 ELISA Kits)+) signaling occurred upstream of the MEKK1 (show MAP3K1 ELISA Kits)-MKK2 pathway. MEKK1 (show MAP3K1 ELISA Kits) was phosphorylated by calcium/calmodulin (show CALM ELISA Kits)-regulated receptor-like kinase (CRLK1), which suggested that CRLK1 is one of candidates located upstream of MEKK1 (show MAP3K1 ELISA Kits).

  4. Data indicate that MEKK2 (show MAP3K2 ELISA Kits) is required for the mekk1 (show MAP3K1 ELISA Kits), mkk1 (show MAP2K1 ELISA Kits) mkk2, and mpk4 (show MAPK4 ELISA Kits) autoimmune phenotypes.

  5. Data suggest that the MEKK1 (show MAP3K1 ELISA Kits)-MKK1 (show MAP2K1 ELISA Kits)/MKK2-MPK4 (show MAPK4 ELISA Kits) kinase cascade negatively regulates MEKK2 (show MAP3K2 ELISA Kits) and activation of MEKK2 (show MAP3K2 ELISA Kits) triggers SUMM2-mediated immune responses.

  6. Data indicate that MKK2 plays a role in abiotic stress tolerance and plant disease resistance.

  7. double loss-of-function mutant (mkk1 (show MAP2K1 ELISA Kits)/2) of MKK1 (show MAP2K1 ELISA Kits) and MKK2 is shown to have marked phenotypes in development and disease

  8. Activation of MPK4 (show MAPK4 ELISA Kits) by flg22 is impaired in the mkk1 (show MAP2K1 ELISA Kits) mkk2 double mutants, suggesting that MKK1 (show MAP2K1 ELISA Kits) and MKK2 function together with MPK4 (show MAPK4 ELISA Kits) and MEKK1 (show MAP3K1 ELISA Kits) in a MAP kinase (show MAPK1 ELISA Kits) cascade to negatively regulate innate immune responses in plants.

MAP2K2 Antigen Profile

Antigen Summary

The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is known to play a critical role in mitogen growth factor signal transduction. It phosphorylates and thus activates MAPK1/ERK2 and MAPK2/ERK3. The activation of this kinase itself is dependent on the Ser/Thr phosphorylation by MAP kinase kinase kinases. Mutations in this gene cause cardiofaciocutaneous syndrome (CFC syndrome), a disease characterized by heart defects, mental retardation, and distinctive facial features similar to those found in Noonan syndrome. The inhibition or degradation of this kinase is also found to be involved in the pathogenesis of Yersinia and anthrax. A pseudogene, which is located on chromosome 7, has been identified for this gene.

Alternative names and synonyms associated with MAP2K2

  • mitogen activated protein kinase kinase 2 (Map2k2) Elisa Kit
  • mitogen-activated protein kinase kinase 2 (MAP2K2) Elisa Kit
  • mitogen-activated protein kinase kinase 2 (Map2k2) Elisa Kit
  • mitogen-activated protein kinase kinase 2 (MKK2) Elisa Kit
  • AA589381 Elisa Kit
  • ATMKK2 Elisa Kit
  • CFC4 Elisa Kit
  • F27B13.50 Elisa Kit
  • F27B13_50 Elisa Kit
  • MAP KINASE KINASE 1 Elisa Kit
  • MAP kinase kinase 2 Elisa Kit
  • MAPKK2 Elisa Kit
  • MEK2 Elisa Kit
  • MK1 Elisa Kit
  • MK2 Elisa Kit
  • MKK2 Elisa Kit
  • PRKMK2 Elisa Kit

Protein level used designations for MAP2K2

ERK activator kinase 2 , MAP kinase kinase 2 , MAPK/ERK kinase 2 , MAPKK 2 , MEK 2 , MEK2 , dual specificity mitogen-activated protein kinase kinase 2 , mitogen-activated protein kinase kinase 2, p45 , MAP kinase/Erk kinase , mitogen activated protein kinase kinase 2 , protein kinase, mitogen activated, kinase 2, p45 , dual specificity mitogen activated protein kinase kinase 2 , mitogen-activated protein kinase kinase type 2

GENE ID SPECIES
58960 Rattus norvegicus
5605 Homo sapiens
26396 Mus musculus
611939 Canis lupus familiaris
396349 Gallus gallus
510434 Bos taurus
829103 Arabidopsis thaliana
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