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Browse our anti-MAP2K3 (MAP2K3) Antibodies

Full name:
anti-Mitogen-Activated Protein Kinase Kinase 3 Antibodies (MAP2K3)
On www.antibodies-online.com are 279 Mitogen-Activated Protein Kinase Kinase 3 (MAP2K3) Antibodies from 27 different suppliers available. Additionally we are shipping MAP2K3 Proteins (14) and MAP2K3 Kits (9) and many more products for this protein. A total of 320 MAP2K3 products are currently listed.
Synonyms:
AW212142, map2k3, MAPKK3, MEK3, MKK3, mMKK3b, Prkmk3, SAPKK-2, SAPKK2, zMKK3
list all antibodies Gene Name GeneID UniProt
MAP2K3 303200  
MAP2K3 5606 P46734
MAP2K3 26397 O09110

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Top referenced anti-MAP2K3 Antibodies

  1. Human Polyclonal MAP2K3 Primary Antibody for IF, IHC (p) - ABIN196862 : Wang, Chen, Liao, Deng, Zhou, Huang, Sun: Sequential activation of the MEK-extracellular signal-regulated kinase and MKK3/6-p38 mitogen-activated protein kinase pathways mediates oncogenic ras-induced premature senescence. in Molecular and cellular biology 2002 (PubMed)
    Show all 2 references for ABIN196862

  2. Human Polyclonal MAP2K3 Primary Antibody for IF, IHC (p) - ABIN197296 : Raingeaud, Whitmarsh, Barrett, Dérijard, Davis: MKK3- and MKK6-regulated gene expression is mediated by the p38 mitogen-activated protein kinase signal transduction pathway. in Molecular and cellular biology 1996 (PubMed)
    Show all 2 references for ABIN197296

  3. Human Polyclonal MAP2K3 Primary Antibody for IHC, ELISA - ABIN1532059 : Dérijard, Raingeaud, Barrett, Wu, Han, Ulevitch, Davis: Independent human MAP-kinase signal transduction pathways defined by MEK and MKK isoforms. in Science (New York, N.Y.) 1995 (PubMed)

  4. Chicken Polyclonal MAP2K3 Primary Antibody for WB - ABIN2777129 : Prickett, Brautigan: Cytokine activation of p38 mitogen-activated protein kinase and apoptosis is opposed by alpha-4 targeting of protein phosphatase 2A for site-specific dephosphorylation of MEK3. in Molecular and cellular biology 2007 (PubMed)

More Antibodies against MAP2K3 Interaction Partners

Human Mitogen-Activated Protein Kinase Kinase 3 (MAP2K3) interaction partners

  1. Our results suggest that asthma is associated with MKK3 over-expression in CD8 (show CD8A Antibodies)+ cells; we have also demonstrated that MKK3 may be critical for airway neutrophilia

  2. MicroRNA-21 promotes hepatocellular carcinoma HepG2 cell proliferation through repression of mitogen-activated protein kinase-kinase 3.

  3. study detected higher MKK3 activation in isolated peripheral blood mononuclear cells from septic patients compared with nonseptic controls

  4. study concludes MAP2K3 is a reproducible obesity locus that may affect body weight via complex mechanisms involving appetite regulation and hypothalamic inflammation

  5. miR-20a acts in a feedback loop to repress the expression of MKK3 and to negatively regulate the p38 pathway-mediated VEGF-induced endothelial cell migration and angiogenesis

  6. Data suggest aberrant MAP2K protein (MKK3, MKK4 (show MAP2K4 Antibodies), MKK6 (show MAP2K6 Antibodies), and MKK7 (show MAP2K7 Antibodies)) expression indicates that altered cellular signal transduction mediated via JNK (show MAPK8 Antibodies) and p38 (show CRK Antibodies) may be common in bladder cancer.

  7. the balance between MKK6 (show MAP2K6 Antibodies) and MKK3 mediates p38 MAPK (show MAPK14 Antibodies) associated resistance to cisplatin in NSCLC

  8. LFA-1 (show ITGAL Antibodies)-induced stabilization of ARE-containing mRNAs in T cells is dependent on HuR (show ELAVL1 Antibodies), and occurs through the Vav-1 (show VAV1 Antibodies), Rac1/2, MKK3 and p38MAPK (show MAPK14 Antibodies) signaling cascade

  9. The p38 MAPK (show MAPK14 Antibodies) pathway transgene is dispensable for the development of natural killer (NK)T cells; however, NKT (show SLC22A6 Antibodies) cell cytokine production and NKT (show SLC22A6 Antibodies)-mediated liver damage are highly dependent on activation of this pathway.

  10. MAP2K3 is identified as a protein to promote senescence in human breast epithelial cells.

Mouse (Murine) Mitogen-Activated Protein Kinase Kinase 3 (MAP2K3) interaction partners

  1. this study demonstrates that MKK3 influences mitochondrial quality by affecting the expression of mitochondrial proteins, including TCA cycle enzymes, and mitophagy, which consequently regulates the inflammatory response.

  2. Exendin-4 treatment improves cardiac function, attenuates cardiac remodeling, and promotes angiogenesis in the infarcted myocardium through MKK3 and Akt-1 (show AKT1 Antibodies) pathway.

  3. Our results suggest that asthma is associated with MKK3 over-expression in CD8 (show CD8A Antibodies)+ cells; we have also demonstrated that MKK3 may be critical for airway neutrophilia

  4. MKK3 and MKK6 (show MAP2K6 Antibodies) differentially regulate bone loss due to estrogen withdrawal. MKK3 directly mediates osteoclastogenesis while MKK6 (show MAP2K6 Antibodies) likely contributes to pro-inflammatory cytokine production that promotes osteoclast formation.

  5. results designate MKK3 as a novel, positive regulator of SCF (show KITLG Antibodies)-induced mast cell proliferation and a critical signaling protein for AP-1 (show JUN Antibodies)-dependent IL-6 (show IL6 Antibodies) production

  6. findings demonstrate a critical role for mitochondria in the pathogenesis of sepsis that involves a previously unrecognized function of MKK3 in mitochondrial quality control

  7. Endothelial MKK3 is neede for inflammatory cell recruitment to the lungs, mitochondrial oxidant-mediated AP-1 (show JUN Antibodies), NF-kappaB (show NFKB1 Antibodies) activation, & ICAM-1 (show ICAM1 Antibodies) expression during LPS (show TLR4 Antibodies) challenge.

  8. mast cell MKK3 signaling contributes to IgE-dependent allergic inflammation and is a specific regulator of FcepsilonRI (show FCER1A Antibodies)-induced IL-4 (show IL4 Antibodies) production.

  9. LFA-1 (show ITGAL Antibodies)-induced stabilization of ARE-containing mRNAs in T cells is dependent on HuR (show ELAVL1 Antibodies), and occurs through the Vav-1 (show VAV1 Antibodies), Rac1/2, MKK3 and p38MAPK (show MAPK14 Antibodies) signaling cascade

  10. Studies identified FOXM1 (show FOXM1 Antibodies) as a key downstream target of Ras-MKK3-p38 (show CRK Antibodies) regulated in vitro cellular invasion.

MAP2K3 Antigen Profile

Antigen Summary

The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is activated by mitogenic and environmental stress, and participates in the MAP kinase-mediated signaling cascade. It phosphorylates and thus activates MAPK14/p38-MAPK. This kinase can be activated by insulin, and is necessary for the expression of glucose transporter. Expression of RAS oncogene is found to result in the accumulation of the active form of this kinase, which thus leads to the constitutive activation of MAPK14, and confers oncogenic transformation of primary cells. The inhibition of this kinase is involved in the pathogenesis of Yersina pseudotuberculosis. Multiple alternatively spliced transcript variants that encode distinct isoforms have been reported for this gene.

Alternative names and synonyms associated with MAP2K3

  • MAP kinase activator XMEK3 (map2k3) antibody
  • mitogen activated protein kinase kinase 3 (Map2k3) antibody
  • mitogen-activated protein kinase kinase 3 (MAP2K3) antibody
  • mitogen-activated protein kinase kinase 3 (Map2k3) antibody
  • mitogen-activated protein kinase kinase 6 (map2k6) antibody
  • AW212142 antibody
  • map2k3 antibody
  • MAPKK3 antibody
  • MEK3 antibody
  • MKK3 antibody
  • mMKK3b antibody
  • Prkmk3 antibody
  • SAPKK-2 antibody
  • SAPKK2 antibody
  • zMKK3 antibody

Protein level used designations for MAP2K3

MAP kinase kinase 3 , MAPK/ERK kinase 3 , MAPKK 3 , MEK 3 , SAPK kinase 2 , dual specificity mitogen-activated protein kinase kinase 3 , stress-activated protein kinase kinase 2 , mitogen activated protein kinase kinase 3 , protein kinase, mitogen-activated, kinase 3 , MAP kinase kinase 6 , MAPKK 6 , dual specificity mitogen-activated protein kinase kinase 6 , mitogen-activated protein kinase kinase 3

GENE ID SPECIES
399150 Xenopus laevis
303200 Rattus norvegicus
5606 Homo sapiens
489547 Canis lupus familiaris
26397 Mus musculus
516039 Bos taurus
416496 Gallus gallus
65239 Danio rerio
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