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Browse our MAP2K4 (MAP2K4) ELISA Kits

Full name:
Mitogen-Activated Protein Kinase Kinase 4 ELISA Kits (MAP2K4)
On www.antibodies-online.com are 8 Mitogen-Activated Protein Kinase Kinase 4 (MAP2K4) ELISA Kits from 4 different suppliers available. Additionally we are shipping MAP2K4 Antibodies (307) and MAP2K4 Proteins (10) and many more products for this protein. A total of 342 MAP2K4 products are currently listed.
Synonyms:
2, 142758_at, ARABIDOPSIS THALIANA MITOGEN-ACTIVATED PROTEIN KINASE KINASE 4, ATMEK4, ATMKK4, CG9738, CT27508, CT38386, D-MKK4, DmelCG12798, Dmel\\CG9738, dMkk4, F19C24.26, F19C24_26, hep, JNKK, JNKK1, Jnkk2, map2k4, MAP KINASE KINASE 4, MAPKK4, Mapkk7, MEK4, Mek7, mitogen-activated protein kinase kinase 4, MKK4, MKK4A-l, Mkk7, Mpk4, PRKMK4, SAPKK-1, SAPKK1, SEK1, SEK1/MKK4, Serk1, SKK1, xmek2, zgc:136500
list all ELISA KIts Gene Name GeneID UniProt
MAP2K4 287398  
MAP2K4 6416 P45985
MAP2K4 26398 P47809

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MAP2K4 (MAP2K4) ELISA Kits by Reactivity

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More ELISA Kits for MAP2K4 Interaction Partners

Fruit Fly (Drosophila melanogaster) Mitogen-Activated Protein Kinase Kinase 4 (MAP2K4) interaction partners

  1. in Drosophila both MAPKKs, Hep/Mkk7 (show MAP2K7 ELISA Kits) and Mkk4, are required to induce JNK (show MAPK8 ELISA Kits) upon TNF (show TNF ELISA Kits) or pro-inflammatory stimulation

Human Mitogen-Activated Protein Kinase Kinase 4 (MAP2K4) interaction partners

  1. The plasma level of protein MAP2K4 was found to suggestively associate negatively with the volume of the left entorhinal cortex in asymptomatic older twins.

  2. MAP2K4 increases human prostate cancer metastasis, and prolonged over expression induces long term changes in cell signaling pathways leading to independence from p38 MAPK (show MAPK14 ELISA Kits) and JNK (show MAPK8 ELISA Kits).

  3. MKK4 is activated in vitro by reduced Trx (show VAC14 ELISA Kits) but not oxidized Trx (show VAC14 ELISA Kits) in the absence of an upstream kinase, suggesting that autophosphorylation of this protein occurs due to reduction of Cys (show DNAJC5 ELISA Kits)-246 and Cys (show DNAJC5 ELISA Kits)-266 by Trx (show VAC14 ELISA Kits).

  4. Data suggest a genetic interaction between MAP2K4 and HLA-DRB1 (show HLA-DRB1 ELISA Kits), and the importance of rs10468473 and MAP2K4 splice variants in the development of autoantibody-positive RA.

  5. knockdown of Sec8 (show EXOC4 ELISA Kits) enhances the binding of JIP4 (show SPAG9 ELISA Kits) to MAPK (show MAPK1 ELISA Kits) kinase 4, thereby decreasing the phosphorylation of MAPK (show MAPK1 ELISA Kits) kinase 4, JNK (show MAPK8 ELISA Kits), and p38 (show CRK ELISA Kits).

  6. Demonstrate that Mkk4 is a negative regulator of the TGF-beta1 (show TGFB1 ELISA Kits) signaling associated with atrial remodeling and arrhythmogenesis with age.

  7. MicroRNA-27a promotes proliferation, migration and invasion by targeting MAP2K4 in human osteosarcoma cells.

  8. Lipopolysaccharide induced miR (show MLXIP ELISA Kits)-181a promotes pancreatic cancer cell migration via targeting PTEN and MAP2K4.

  9. Single nucleotide polymorphisms in MAP2K4 gene is associated with gastric cancer.

  10. Arrestin-3 (show ARRB2 ELISA Kits) directly interacts with MKK7 (show MAP2K7 ELISA Kits) and promotes JNK3alpha2 phosphorylation by both MKK4 and MKK7 (show MAP2K7 ELISA Kits) in vitro as well as in intact cells.

Mouse (Murine) Mitogen-Activated Protein Kinase Kinase 4 (MAP2K4) interaction partners

  1. Demonstrate that Mkk4 is a negative regulator of the TGF-beta1 (show TGFB1 ELISA Kits) signaling associated with atrial remodeling and arrhythmogenesis with age.

  2. This study provides compelling evidence for the pivotal roles of the ZPK/DLK (show MAP3K12 ELISA Kits) and MKK4/MAP2K4-dependent mechanism in axotomy-induced motoneuron death in neonates.

  3. The loss of mkk4 and mkk7 (show MAP2K7 ELISA Kits) locks damaged exocrine cells in a permanently de-differentiated state.

  4. Studies identify the dual-specific kinase MKK4 as a master regulator of liver regeneration. MKK4 silencing robustly increased the regenerative capacity of hepatocytes in mouse models of liver regeneration and acute and chronic liver failure.

  5. MicroRNA-92a negatively regulates Toll (show TLR4 ELISA Kits)-like receptor (TLR)-triggered inflammatory response in macrophages by targeting MKK4 kinase

  6. Distinct signaling properties of mitogen-activated protein kinase kinases 4 (MKK4) and 7 (MKK7) in embryonic stem cell (ESC) differentiation.

  7. MKK4/7 and JNK1 (show MAPK8 ELISA Kits)/2 played regulatory role in cytoskeleton reorganization during vaccinia virus infection.

  8. These data support a model in which MKK4 activation at the metastatic site causes a cell-cycle arrest.

  9. Mitogen-activated protein kinase kinase 4 deficiency in cardiomyocytes causes connexin 43 (show GJA1 ELISA Kits) reduction and couples hypertrophic signals to ventricular arrhythmogenesis.

  10. 7,3',4'-Trihydroxyisoflavone, a metabolite of the soy isoflavone daidzein, suppresses ultraviolet B-induced skin cancer by targeting Cot (show MAP3K8 ELISA Kits) and MKK4

Arabidopsis thaliana Mitogen-Activated Protein Kinase Kinase 4 (MAP2K4) interaction partners

  1. our data indicate that EDR1 (show PHC1 ELISA Kits) physically associates with MKK4/MKK5 (show MAP2K5 ELISA Kits) and negatively regulates the MAPK (show MAPK1 ELISA Kits) cascade to fine-tune plant innate immunity.

  2. Results suggest that the YDA-MKK4/MKK5 (show MAP2K5 ELISA Kits)-MPK3 (show MAPK3 ELISA Kits)/MPK6 (show MAPK6 ELISA Kits) cascade functions downstream of the ER receptor in regulating localized cell proliferation, which further shapes the morphology of plant organs.

  3. MKK4 is involved in the osmotic-stress response via its regulation of MPK3 (show MAPK3 ELISA Kits) activity.

  4. MKK4 is a key regulator of stomatal development and patterning.

MAP2K4 Antigen Profile

Antigen Summary

This gene encodes a dual specificity protein kinase that belongs to the Ser/Thr protein kinase family. This kinase is a direct activator of MAP kinases in response to various environmental stresses or mitogenic stimuli. It has been shown to activate MAPK8/JNK1, MAPK9/JNK2, and MAPK14/p38, but not MAPK1/ERK2 or MAPK3/ERK3. This kinase is phosphorylated, and thus activated by MAP3K1/MEKK. The knockout studies in mice suggested the roles of this kinase in mediating survival signal in T cell development, as well as in the organogenesis of liver.

Alternative names and synonyms associated with MAP2K4

  • mitogen-activated protein kinase kinase 4 (map2k4) Elisa Kit
  • MAP kinase kinase 4 (Mkk4) Elisa Kit
  • CG12798 (CG12798) Elisa Kit
  • mitogen activated protein kinase kinase 4 (Map2k4) Elisa Kit
  • mitogen activated protein kinase kinase 7 (Map2k7) Elisa Kit
  • mitogen-activated protein kinase kinase 4 (MAP2K4) Elisa Kit
  • mitogen-activated protein kinase kinase 4 (Map2k4) Elisa Kit
  • mitogen-activated protein kinase kinase 4 (MKK4) Elisa Kit
  • mitogen-activated protein kinase kinase 4a (map2k4a) Elisa Kit
  • 2 Elisa Kit
  • 142758_at Elisa Kit
  • ARABIDOPSIS THALIANA MITOGEN-ACTIVATED PROTEIN KINASE KINASE 4 Elisa Kit
  • ATMEK4 Elisa Kit
  • ATMKK4 Elisa Kit
  • CG9738 Elisa Kit
  • CT27508 Elisa Kit
  • CT38386 Elisa Kit
  • D-MKK4 Elisa Kit
  • DmelCG12798 Elisa Kit
  • Dmel\\CG9738 Elisa Kit
  • dMkk4 Elisa Kit
  • F19C24.26 Elisa Kit
  • F19C24_26 Elisa Kit
  • hep Elisa Kit
  • JNKK Elisa Kit
  • JNKK1 Elisa Kit
  • Jnkk2 Elisa Kit
  • map2k4 Elisa Kit
  • MAP KINASE KINASE 4 Elisa Kit
  • MAPKK4 Elisa Kit
  • Mapkk7 Elisa Kit
  • MEK4 Elisa Kit
  • Mek7 Elisa Kit
  • mitogen-activated protein kinase kinase 4 Elisa Kit
  • MKK4 Elisa Kit
  • MKK4A-l Elisa Kit
  • Mkk7 Elisa Kit
  • Mpk4 Elisa Kit
  • PRKMK4 Elisa Kit
  • SAPKK-1 Elisa Kit
  • SAPKK1 Elisa Kit
  • SEK1 Elisa Kit
  • SEK1/MKK4 Elisa Kit
  • Serk1 Elisa Kit
  • SKK1 Elisa Kit
  • xmek2 Elisa Kit
  • zgc:136500 Elisa Kit

Protein level used designations for MAP2K4

CG9738-PA , CG9738-PB , CG9738-PC , JNK kinase 2 , Map kinase kinase 4 , Mkk4-PA , Mkk4-PB , Mkk4-PC , drosophila MAP kinase kinase 4 , CG12798 , CG12798-PA , MAP2K4delta , SAPK/ERK kinase 1 , dual specificity mitogen-activated protein kinase kinase 4 , JNK-activating kinase 2 , JNKK 2 , MAP kinase kinase 7 , MAPK/ERK kinase 7 , MAPKK 7 , MEK 7 , c-Jun N-terminal kinase kinase 2 , dual specificity mitogen-activated protein kinase kinase 7 , JNK activating kinase 1 , JNK-activated kinase 1 , JNK-activating kinase 1 , MAP kinase kinase 4 , MAPK/ERK kinase 4 , MAPKK 4 , MEK 4 , c-Jun N-terminal kinase kinase 1 , stress-activated protein kinase kinase 1 , C-JUN N-terminal kinase kinase 1 , JNK kinase 1 , JNKK 1 , SAPK/Erk/kinase 1 , mitogen activated protein kinase kinase 4, variant 1 , mitogen-activated protein kinase kinase 4 , mkk4a

GENE ID SPECIES
100135013 Xenopus (Silurana) tropicalis
41020 Drosophila melanogaster
3355004 Drosophila melanogaster
287398 Rattus norvegicus
363855 Rattus norvegicus
6416 Homo sapiens
26398 Mus musculus
489508 Canis lupus familiaris
841591 Arabidopsis thaliana
403052 Danio rerio
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