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anti-Human MAP2K5 antibody for Immunocytochemistry

Recommended MAP2K5 Antibody (supplied by: Log in to see )

Antigen
Mitogen-Activated Protein Kinase Kinase 5 (MAP2K5) Antibodies
  • AI324775
  • AI428457
  • ARABIDOPSIS THALIANA MITOGEN-ACTIVATED PROTEIN KINASE KINASE 5
  • ATMAP2K_ALPHA
  • ATMEK5
  • ATMKK5
  • fb73f02
  • HsT17454
  • MAP2K_A
  • MAP KINASE KINASE 5
  • MAP kinase kinase 5
  • MAPKK5
  • Mapkk5
  • Mek5
  • MEK5
  • PRKMK5
  • Prkmk5
  • wu:fb73f02
  • zgc:172137
Reactivity
Human
154
76
75
11
9
7
6
5
3
3
3
3
2
2
1
Host
Rabbit
155
16
Clonality
Monoclonal
Conjugate
This MAP2K5 antibody is un-conjugated
9
9
9
5
5
5
5
5
5
5
5
4
4
4
4
Application
Immunocytochemistry (ICC), Immunofluorescence (IF), Western Blotting (WB)
111
54
47
29
23
21
4
2
2
1
1
Supplier
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Available images

Catalog No. ABIN189531
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Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0009965779 ABIN2970174 ICC IF IHC WB Rabbit IgG Log in to see Polyclonal
0.0009965779 ABIN4333506 ICC IF IHC IHC (p) WB Rabbit IgG Log in to see Polyclonal

Similar anti-MAP2K5 Antibodies

Application / Reactivity Human
ELISA 46 Antibodies
Enzyme Immunoassay (EIA) 1 Antibodies
Immunochromatography (IC) 1 Antibodies
Immunocytochemistry (ICC) 3 Antibodies
Immunofluorescence (IF) 22 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 54 Antibodies
Immunohistochemistry (IHC) 29 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 23 Antibodies
Immunoprecipitation (IP) 4 Antibodies
Proximity Ligation Assay (PLA) 2 Antibodies
Western Blotting (WB) 96 Antibodies

General

Antigen Mitogen-Activated Protein Kinase Kinase 5 (MAP2K5) Antibodies
Reactivity Human
(154), (76), (75), (11), (9), (7), (6), (5), (3), (3), (3), (3), (2), (2), (1)
Host Rabbit
(155), (16)
Clonality (Clone)
Monoclonal   ( )
Conjugate This MAP2K5 antibody is un-conjugated
(9), (9), (9), (5), (5), (5), (5), (5), (5), (5), (5), (4), (4), (4), (4)
Application Immunocytochemistry (ICC), Immunofluorescence (IF), Western Blotting (WB)
(111), (54), (47), (29), (23), (21), (4), (2), (2), (1), (1)
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Product Details anti-MAP2K5 Antibody

Target Details MAP2K5 Application Details Handling Images
No Cross-Reactivity Mouse (Murine), Rat (Rattus)
Purification Tissue culture supernatant
Immunogen A synthetic peptide corresponding to residues within human MKK5 was used as an immunogen.
Clone EP648Y
Isotype IgG

Target Details MAP2K5

Product Details anti-MAP2K5 Antibody Application Details Handling Images back to top
Antigen
Alternative Name MAP2K5 (MAP2K5 Antibody Abstract)
Background Mitogen-acitvated protein kinase kinase 5 (MKK5) belongs to the serine/threonineprotein kinase family and the MAPK kinase subfamily (MAP2K, MKK or MEKs). MAPKsrequire dual phosphorylation on threonine and tyrosine residues, an activation stepcarried out by MAPK kinase (1-2). The MAPK cascade plays an important role insignaling defense responses. Of the MKK family members, MKK5 exhibits the closesthomology to MEK1 and MEK2, with 46% amino acid identity in the catalytic domain (3)MKK has been show to activate extracellular-signal-regulated protein kinase 5 (ERK5).Also, activated ERK5 phosphorylates mitogen- MKK5 extensively at Ser129, Ser137,Ser142 and Ser149, which are located within the region in MKK5 that is thought tointeract with ERK5 (3). There have also been findings to that the MEK5 (MKK5)/ERK5(BMK) pathway may play a role in prostate cancer (5). Alternate Names: anti-Dual specificity mitogen activated protein kinase kinase 5 antibody, anti-EC 2.7.12.2antibody, anti-MAP kinase kinase 5 antibody, anti-MAP kinase kinase MEK5b antibody,anti-MAP2K5 antibody, anti-MAPK/ERK kinase 5 antibody, anti-MAPKK5 antibody,anti-PRKMK5 antibody.
Gene Symbol: MAP2K5
Gene ID 5607, 23938, 29568
Research Area Kinases/Phosphatases
Pathways MAPK Signaling, Neurotrophin Signaling Pathway

Application Details

Product Details anti-MAP2K5 Antibody Target Details MAP2K5 Handling Images back to top
Application Notes This product is useful for: Western Blot, Immunocytochemistry. In Western blot this antibody detects a band at approximately 49kDa.
Recommended dilutions: Immunocytochemistry/Immunofluorescence 1:100-250, Western Blot 1:1000-10000
Restrictions For Research Use only

Handling

Product Details anti-MAP2K5 Antibody Target Details MAP2K5 Application Details Images back to top
Format Liquid
Buffer PBS 49 % , Glycerol 50 % , BSA 0.05 % , Sodium Azide
Preservative Sodium azide
Precaution of Use WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Handling Advice Avoid freeze-thaw cycles
Storage -20 °C
Storage Comment -20 °C.

Images

Product Details anti-MAP2K5 Antibody Target Details MAP2K5 Application Details Handling back to top
Supplier Images
Western Blotting (WB) image for anti-MAP2K5 antibody (Mitogen-Activated Protein Kinase Kinase 5) (ABIN189531) Western blot analysis on HeLa cell lysate using anti-MKK5 RabMAb (cat. # 110-57206), ...
Immunofluorescence (IF) image for anti-MAP2K5 antibody (Mitogen-Activated Protein Kinase Kinase 5) (ABIN189531) Immunofluorescent staining of HeLa using anti-MKK5 RabMAb (cat. # 110-57206).