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anti-Rat (Rattus) MAP2K6 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended MAP2K6 Antibody (supplied by: Log in to see )

Antigen
Mitogen-Activated Protein Kinase Kinase 6 (MAP2K6) Antibodies
  • ANQ1
  • ARABIDOPSIS NQK1
  • ARABIDOPSIS THALIANA MAP KINASE KINASE 6
  • ATMKK6
  • map2k3
  • MAP kinase kinase 6
  • MAPKK6
  • MEK6
  • MIK19.2
  • MIK19_2
  • MKK3
  • Mkk6
  • MKK6
  • PRKMK6
  • Prkmk6
  • SAPKK-3
  • SAPKK3
  • zMKK3
Epitope
pSer207
48
33
15
9
6
5
4
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Rat (Rattus)
168
97
77
3
2
2
Host
Rabbit
158
31
2
Clonality
Polyclonal
Conjugate
This MAP2K6 antibody is un-conjugated
5
5
5
3
3
3
2
2
2
2
2
2
2
2
2
Application
Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
153
69
69
40
23
22
15
13
7
3
2
1
Supplier
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Catalog No. ABIN196864
$ 357.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.00089488085 ABIN272204 IF IHC (p) WB Rabbit Log in to see Polyclonal
0.00089488085 ABIN743890 IHC (p) WB Biotin Rabbit IgG pSer207 Log in to see Polyclonal
0.00089488085 ABIN743897 IHC (p) WB HRP Rabbit IgG pSer207 Log in to see Polyclonal
0.00089488085 ABIN743888 IF (p) IHC (p) WB Rabbit IgG pSer207 Log in to see Polyclonal
0.00089488085 ABIN743903 IF (p) IHC (p) WB Rabbit IgG pSer202 Log in to see Polyclonal
0.00089488085 ABIN681570 IHC (p) WB Biotin Rabbit IgG Log in to see Polyclonal
0.00089488085 ABIN681577 IHC (p) WB HRP Rabbit IgG Log in to see Polyclonal
0.00089488085 ABIN681568 IF (p) IHC (p) WB Rabbit IgG Log in to see Polyclonal
0.00089488085 ABIN1736713 IHC (p) IP WB Rabbit IgG C-Term Log in to see Polyclonal

Top referenced anti-MAP2K6 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Similar anti-MAP2K6 Antibodies

Application / Reactivity Rat (Rattus) Human
ELISA 17 Antibodies 56 Antibodies
Immunochromatography (IC) 1 Antibodies 1 Antibodies
Immunocytochemistry (ICC) 4 Antibodies 15 Antibodies
Immunofluorescence (IF) 21 Antibodies 41 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 23 Antibodies 23 Antibodies
Immunohistochemistry (IHC) 37 Antibodies 70 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 10 Antibodies 23 Antibodies
Immunoprecipitation (IP) 3 Antibodies
Western Blotting (WB) 54 Antibodies
Enzyme Immunoassay (EIA) 3 Antibodies
Flow Cytometry (FACS) 7 Antibodies

General

Antigen Mitogen-Activated Protein Kinase Kinase 6 (MAP2K6) Antibodies
Epitope pSer207
(48), (33), (15), (9), (6), (5), (4), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Rat (Rattus)
(168), (97), (77), (3), (2), (2)
Host Rabbit
(158), (31), (2)
Clonality
Polyclonal
Conjugate This MAP2K6 antibody is un-conjugated
(5), (5), (5), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Application Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(153), (69), (69), (40), (23), (22), (15), (13), (7), (3), (2), (1)
Pubmed 2 references available
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Product Details anti-MAP2K6 Antibody

Target Details MAP2K6 Application Details Handling References for anti-MAP2K6 Antibody (ABIN196864) Images
Specificity This antibody detects endogenous levels of MKK6 only when phosphorylated at serine207.
Purification Immunoaffinity Chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Immunogen Synthetic phosphopeptide derived from Human MKK6 around the phosphorylation site of Serine 207 (V-D-Sp-V-A).

Target Details MAP2K6

Product Details anti-MAP2K6 Antibody Application Details Handling References for anti-MAP2K6 Antibody (ABIN196864) Images back to top
Antigen
Alternative Name MAP2K6 (MAP2K6 Antibody Abstract)
Background Mitogen activated protein kinase kinase 6 (MEK6 or MKK6) belongs to the serine/threonine protein kinase family and the MAPK kinase subfamily (MAP2K, MKK or MEKs). MEK6, closely related to MEK3, catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in MAP kinase p38, thus activating it, in response to inflammatory cytokines and environmental stress. As an essential component of p38 MAP kinase mediated signal transduction pathway, this protein is involved in many cellular processes such as stress induced cell cycle arrest, transcription activation and apoptosis.Synonyms: Dual specificity mitogen-activated protein kinase kinase 6, MAP kinase kinase 6, MAPK/ERK kinase 6, MAPKK 6, MEK6, MKK6, SAPKK3
Gene ID 5608
NCBI Accession NP_002749
UniProt P52564
Research Area Kinases/Phosphatases
Pathways MAPK Signaling, TLR Signaling

Application Details

Product Details anti-MAP2K6 Antibody Target Details MAP2K6 Handling References for anti-MAP2K6 Antibody (ABIN196864) Images back to top
Application Notes Suitable for use in Western blot (1: 500approx. 1: 1000) and Immunohistochemistry (1: 50approx. 1: 100).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-MAP2K6 Antibody Target Details MAP2K6 Application Details References for anti-MAP2K6 Antibody (ABIN196864) Images back to top
Concentration 1.0 mg/mL
Buffer PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % Sodium Azide and 50 % Glycerol
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage -20 °C
Storage Comment Store the antibody (in aliquots) at -20 °C.

References for anti-MAP2K6 Antibody (ABIN196864)

Product Details anti-MAP2K6 Antibody Target Details MAP2K6 Application Details Handling Images back to top
Background publications

Wang, Chen, Liao, Deng, Zhou, Huang, Sun: "Sequential activation of the MEK-extracellular signal-regulated kinase and MKK3/6-p38 mitogen-activated protein kinase pathways mediates oncogenic ras-induced premature senescence." in: Molecular and cellular biology, Vol. 22, Issue 10, pp. 3389-403, 2002

Raingeaud, Whitmarsh, Barrett, Dérijard, Davis: "MKK3- and MKK6-regulated gene expression is mediated by the p38 mitogen-activated protein kinase signal transduction pathway." in: Molecular and cellular biology, Vol. 16, Issue 3, pp. 1247-55, 1996

Images

Product Details anti-MAP2K6 Antibody Target Details MAP2K6 Application Details Handling References for anti-MAP2K6 Antibody (ABIN196864) back to top
Supplier Images
 image for anti-MAP2K6 antibody (Mitogen-Activated Protein Kinase Kinase 6) (pSer207) (ABIN196864) anti-Mitogen-Activated Protein Kinase Kinase 6 (MAP2K6) (pSer207) antibody
 image for anti-MAP2K6 antibody (Mitogen-Activated Protein Kinase Kinase 6) (pSer207) (ABIN196864) anti-Mitogen-Activated Protein Kinase Kinase 6 (MAP2K6) (pSer207) antibody (Image 2)
 image for anti-MAP2K6 antibody (Mitogen-Activated Protein Kinase Kinase 6) (pSer207) (ABIN196864) anti-Mitogen-Activated Protein Kinase Kinase 6 (MAP2K6) (pSer207) antibody (Image 3)