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anti-Rat (Rattus) MAP3K1 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended MAP3K1 Antibody (supplied by: Log in to see )

Antigen
Mitogen-Activated Protein Kinase Kinase Kinase 1 (MAP3K1) Antibodies
  • ARAKIN
  • ATMEKK1
  • MAP3K1
  • MAPK/ERK kinase kinase 1
  • MAPKKK1
  • MAPKKK8
  • MEKK
  • Mekk
  • Mekk1
  • MEKK1
  • MEKK 1
  • SRXY6
  • T15F16.5
  • T15F16_5
Reactivity
Human, Rat (Rattus)
114
49
25
6
6
4
1
1
Host
Rabbit
107
31
Clonality
Polyclonal
Conjugate
This MAP3K1 antibody is un-conjugated
7
7
7
7
6
6
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
98
60
37
30
25
18
13
3
2
2
2
1
1
Supplier
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Available images

Catalog No. ABIN615074
$ 500.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0008982679 ABIN259900 IHC (p) IHC WB Rabbit Log in to see Polyclonal
0.0008982679 ABIN1736716 IHC (p) WB Rabbit IgG Log in to see Polyclonal
0.0008982679 ABIN3031846 IHC (p) WB Rabbit IgG C-Term Log in to see Polyclonal

Similar anti-MAP3K1 Antibodies

Application / Reactivity Rat (Rattus) Human
ELISA 12 Antibodies 45 Antibodies
Immunofluorescence (IF) 4 Antibodies 13 Antibodies
Immunohistochemistry (IHC) 13 Antibodies 19 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 4 Antibodies 37 Antibodies
Western Blotting (WB) 23 Antibodies 81 Antibodies
Dot Blot (DB) 18 Antibodies
Enzyme Immunoassay (EIA) 2 Antibodies
Flow Cytometry (FACS) 25 Antibodies
Immunocytochemistry (ICC) 3 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 1 Antibodies
Immunoprecipitation (IP) 2 Antibodies
Proximity Ligation Assay (PLA) 2 Antibodies

General

Antigen Mitogen-Activated Protein Kinase Kinase Kinase 1 (MAP3K1) Antibodies
Reactivity Human, Rat (Rattus)
(114), (49), (25), (6), (6), (4), (1), (1)
Host Rabbit
(107), (31)
Clonality
Polyclonal
Conjugate This MAP3K1 antibody is un-conjugated
(7), (7), (7), (7), (6), (6), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(98), (60), (37), (30), (25), (18), (13), (3), (2), (2), (2), (1), (1)
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Product Details anti-MAP3K1 Antibody

Target Details MAP3K1 Application Details Handling Images
Specificity This antibody reacts to MAP Kinase Kinase Kinase 1 (MEKK1) (MAP3K1).
Purification Immunoaffinity Chromatography
Immunogen MAP3K1 antibody was raised against synthetic peptide derived from the sequence of mouse MEKK1, conjugated to KLH Genename: MAP3K1

Target Details MAP3K1

Product Details anti-MAP3K1 Antibody Application Details Handling Images back to top
Antigen
Alternative Name MAP3K1 (MAP3K1 Antibody Abstract)
Background MEKK1, a MAP3K type protein kinase, is a member of the stress-activated protein kinase (SAPK) pathways which convey pro-apoptotic signals. The protein consists of a C-terminal protein kinase domain and an extensive N-terminal domain that includes two proline-rich segments containing putative binding sites for proteins with SH3 domains, a consensus binding site for 14-3-3 proteins, two PH domains and an acid rich motif with two sites for cleavage by proapoptotic caspase cysteine proteases. MEKK1 activates MKK4/MAP2K4 and, to a lesser extent, MKK7/MAP2K7 in the SAPK cascade. MEKK1 also has been shown to activate the transcription factor CCAAT/enhancer-binding protein-beta-dependent gene expression via MEK1-ERK1/2 kinases in response to IFN-gamma. In MEKK1 (-/-) mouse embryonic stem cells the response of JNK to microtubule disruption, cold stress, hyperosmolarity and serum factors is lost or altered, and the response of ERK to hyperosmolarity and serum factors is diminished.Synonyms: MAPK/ERK kinase kinase 1, MAPKKK1, MEKK, MEKK1, Mitogen-activated protein kinase kinase kinase 1
Gene ID 4214
NCBI Accession NP_005912
UniProt Q13233
Research Area Kinases/Phosphatases
Pathways MAPK Signaling, Interferon-gamma Pathway, Caspase Cascade in Apoptosis, TLR Signaling, Fc-epsilon Receptor Signaling Pathway

Application Details

Product Details anti-MAP3K1 Antibody Target Details MAP3K1 Handling Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-MAP3K1 Antibody Target Details MAP3K1 Application Details Images back to top
Buffer 25 mM sodium borate, 100 mM boric acid, pH 8.4, 75 mM NaCl, 5 mM EDTA
Handling Advice Avoid repeated freezing and thawing.
Storage -20 °C

Images

Product Details anti-MAP3K1 Antibody Target Details MAP3K1 Application Details Handling back to top
Supplier Images
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-MAP3K1 antibody (Mitogen-Activated Protein Kinase Kinase Kinase 1) (ABIN615074) Human Heart (formalin-fixed, paraffin-embedded) stained with MAP3K1at 10 µg/ml follow...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-MAP3K1 antibody (Mitogen-Activated Protein Kinase Kinase Kinase 1) (ABIN615074) Human Testis (formalin-fixed, paraffin-embedded) stained with MAP3K1at 10 µg/ml follo...
Western Blotting (WB) image for anti-MAP3K1 antibody (Mitogen-Activated Protein Kinase Kinase Kinase 1) (ABIN615074) Lane 1: MWM Lane 2: Rat Liver Lane 3: Mouse Liver