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Browse our anti-MAP3K2 (MAP3K2) Antibodies

Full name:
anti-Mitogen-Activated Protein Kinase Kinase Kinase 2 Antibodies (MAP3K2)
On www.antibodies-online.com are 49 Mitogen-Activated Protein Kinase Kinase Kinase 2 (MAP3K2) Antibodies from 14 different suppliers available. Additionally we are shipping MAP3K2 Proteins (5) and many more products for this protein. A total of 60 MAP3K2 products are currently listed.
Synonyms:
9630061B06Rik, AI585793, MEKK2, Mekk2b
list all antibodies Gene Name GeneID UniProt
MAP3K2 171492  
MAP3K2 10746 Q9Y2U5
MAP3K2 26405  

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All available anti-MAP3K2 Antibodies

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Top referenced anti-MAP3K2 Antibodies

  1. Human Monoclonal MAP3K2 Primary Antibody for ICC, ELISA - ABIN969272 : Kurada, Li, Mulherkar, Subramanian, Prasad, Prabhakar: MADD, a splice variant of IG20, is indispensable for MAPK activation and protection against apoptosis upon tumor necrosis factor-alpha treatment. in The Journal of biological chemistry 2009 (PubMed)
    Show all 2 references for ABIN969272

  2. Human Monoclonal MAP3K2 Primary Antibody for EIA, IF - ABIN1108129 : Spathelf, Rautenbach: Anti-listerial activity and structure-activity relationships of the six major tyrocidines, cyclic decapeptides from Bacillus aneurinolyticus. in Bioorganic & medicinal chemistry 2009 (PubMed)
    Show all 2 references for ABIN1108129

  3. Dog (Canine) Polyclonal MAP3K2 Primary Antibody for WB - ABIN2783679 : Wissing, Jänsch, Nimtz, Dieterich, Hornberger, Kéri, Wehland, Daub: Proteomics analysis of protein kinases by target class-selective prefractionation and tandem mass spectrometry. in Molecular & cellular proteomics : MCP 2007 (PubMed)

More Antibodies against MAP3K2 Interaction Partners

Human Mitogen-Activated Protein Kinase Kinase Kinase 2 (MAP3K2) interaction partners

  1. SMYD3 (show SMYD3 Antibodies)-mediated methylation of MAP3K2 increases mutant K-Ras (show HRAS Antibodies)-induced activation of ERK1/2 (show MAPK1/3 Antibodies). (Review)

  2. Restoration of miR17/20a in solid tumor cells enhances the natural killer cell antitumor activity by targeting Mekk2

  3. HBXIP (show HBXIP Antibodies) activated ERK1/2 (show MAPK1/3 Antibodies) through up-regulating MEKK2.

  4. MEKK2 has a novel function as a regulator of ubiquitylation-dependent paxillin (show PXN Antibodies) redistribution in breast tumour cells.

  5. EBV microRNA BART (show BSND Antibodies) 18-5p targets MAP3K2 to facilitate persistence in vivo by inhibiting viral replication in B cells.

  6. Inhibitors of apoptosis proteins regulate myogenic differentiation by directly suppressing MEKK2/3-MEK5 (show MAP2K5 Antibodies)-ERK5 (show MAPK7 Antibodies) signaling.

  7. methylation of MAP3K2 by SMYD3 increases MAP kinase signalling and promotes the formation of Ras-driven carcinomas

  8. results strongly support a role for MEKK2 as a regulator of signaling that modulates breast tumor cell spread area and migration through control of focal adhesion stability

  9. Data suggest that MEKK2 and MLK3 (show MAP3K11 Antibodies) represent untargeted kinases in tumor biology for potential therapeutic development.

  10. Hepatitis B virus X protein enhances the growth of hepatoma cells through upregulation of MEKK2.

Mouse (Murine) Mitogen-Activated Protein Kinase Kinase Kinase 2 (MAP3K2) interaction partners

  1. FGF2 (show FGF2 Antibodies)/MEKK2 pathway mediates an alternative nonclassical pathway for beta-catenin (show CTNNB1 Antibodies) activation, and this pathway is a key regulator of bone formation by osteoblasts

  2. Stk38 (show STK38 Antibodies) protein kinase (show CDK7 Antibodies) has a role in inhibiting TLR9 (show TLR9 Antibodies)-activated inflammatory responses by promoting MEKK2 ubiquitination in macrophages

  3. methylation of MAP3K2 by SMYD3 increases MAP kinase signalling and promotes the formation of Ras-driven carcinomas

  4. MEKK2 is regulated through a phosphorylation-dependent association with 14-3-3 (show YWHAQ Antibodies), a group of adapters that modulate dimerization and association between proteins

  5. MEKK2 signaling contributes to right ventricular hypertrophy and altered myocardial inflammatory gene expression in response to hypoxia-induced pulmonary hypertension.

  6. MEKK2 alone can suppress T-cell TGF-beta (show TGFB1 Antibodies) responses. MEKK2 or MEKK3 (show MAP3K3 Antibodies) can cause ERK1/2 (show MAPK1/3 Antibodies) to phosphorylate SMAD2 (show SMAD2 Antibodies)/3 and suppress R-SMAD (show SMAD1 Antibodies)-dependent transcription. MEKK2 and MEKK3 (show MAP3K3 Antibodies) play overlapping roles in regulating Th-cell differentiation via TGF-beta (show TGFB1 Antibodies)

  7. Data show that HDAC4 (show HDAC5 Antibodies) binds and promotes the deacetylation and activation of a key MAP3 kinase, MEKK2.

  8. Data from experiments with Mekk2(-/-) mice show that MEKK2 may be required for controlling the strength of T cell receptor/CD3 (show CD3E Antibodies) signaling.

  9. PB1 (show GPR97 Antibodies) domain mediates the association of MEKK2 and MEKK3 (show MAP3K3 Antibodies) with MEK5 (show MAP2K5 Antibodies) and that the respective PB1 (show GPR97 Antibodies) domains of these kinases are critical for regulation of the ERK5 (show MAPK7 Antibodies) pathway.

  10. Rap1 (show TERF2IP Antibodies) and MEKK2 are critical upstream signaling molecules mediating BDNF (show BDNF Antibodies) stimulation of ERK5 (show MAPK7 Antibodies) in central nervous system neurons

MAP3K2 Antigen Profile

Antigen Summary

The protein encoded by this gene is a member of serine/threonine protein kinase family. This kinase preferentially activates other kinases involved in the MAP kinase signaling pathway. This kinase has been shown to directly phosphorylate and activate Ikappa B kinases, and thus plays a role in NF-kappa B signaling pathway. This kinase has also been found to bind and activate protein kinase C-related kinase 2, which suggests its involvement in a regulated signaling process.

Alternative names and synonyms associated with MAP3K2

  • mitogen activated protein kinase kinase kinase 2 (Map3k2) antibody
  • mitogen-activated protein kinase kinase kinase 2 (MAP3K2) antibody
  • mitogen-activated protein kinase kinase kinase 2 (Map3k2) antibody
  • 9630061B06Rik antibody
  • AI585793 antibody
  • MEKK2 antibody
  • Mekk2b antibody

Protein level used designations for MAP3K2

mitogen-activated protein kinase kinase kinase 2 , MAP/ERK kinase kinase 2 , MAPK/ERK kinase kinase 2 , MEK kinase 2 , MEKK 2 , mitogen activated protein kinase kinase kinase 2 , protein kinase MEKK2b

GENE ID SPECIES
171492 Rattus norvegicus
10746 Homo sapiens
26405 Mus musculus
612902 Canis lupus familiaris
100050628 Equus caballus
504592 Bos taurus
424225 Gallus gallus
100621234 Sus scrofa
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