anti-Human MAP4K3 antibody for Enzyme Immunoassay

Recommended MAP4K3 Antibody (supplied by: Log in to see )

Antigen
Mitogen-Activated Protein Kinase Kinase Kinase Kinase 3 (MAP4K3) Antibodies
  • GLK
  • MAPKKKK3
  • MEKKK 3
  • MEKKK3
  • RAB8IPL1
  • 4833416M01Rik
  • 4833416M07Rik
  • 9530052P13Rik
  • Glk
  • mitogen-activated protein kinase kinase kinase kinase 3
  • MAP4K3
  • Map4k3
Epitope
C-Term
15
8
8
7
3
2
2
1
1
1
1
Reactivity
Human
79
26
15
Host
Rabbit
67
12
Clonality
Polyclonal
Conjugate
This MAP4K3 antibody is un-conjugated
6
5
5
5
5
5
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
74
46
43
36
13
2
1
1
1
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Catalog No. ABIN360428
$ 390.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN317719 EIA WB Rabbit Log in to see Polyclonal

General

Antigen Mitogen-Activated Protein Kinase Kinase Kinase Kinase 3 (MAP4K3) Antibodies
Epitope C-Term
(15), (8), (8), (7), (3), (2), (2), (1), (1), (1), (1)
Reactivity Human
(79), (26), (15)
Host Rabbit
(67), (12)
Clonality
Polyclonal
Conjugate This MAP4K3 antibody is un-conjugated
(6), (5), (5), (5), (5), (5)
Application Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(74), (46), (43), (36), (13), (2), (1), (1), (1)
Pubmed 1 reference available
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Product Details anti-MAP4K3 Antibody

Target Details MAP4K3 Application Details Handling References for anti-MAP4K3 antibody (ABIN360428) Images
Specificity This antibody reacts to GLK.
Purification Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
Immunogen This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human GLK.
Isotype Ig

Target Details MAP4K3

Product Details anti-MAP4K3 Antibody Application Details Handling References for anti-MAP4K3 antibody (ABIN360428) Images back to top
Antigen
Alternative Name MAP4K3 (MAP4K3 Antibody Abstract)
Background GLK is a member of the Ste20 family of serine/threonine protein kinases. The protein belongs to the subfamily that consists of members, such as germinal center kinase (GCK), that are characterized by an N-terminal catalytic domain and C-terminal regulatory domain. The kinase activity of the encoded protein can be stimulated by UV radiation and tumor necrosis factor-alpha. The protein specifically activates the c-Jun N-terminal kinase (JNK) signaling pathway. Evidence suggests that it functions upstream of mitogen-activated protein kinase kinase kinase 1 (MEKK1). This gene previously was referred to as RAB8-interacting protein-like 1 (RAB8IPL1), but it has been renamed mitogen-activated protein kinase kinase kinase kinase 3 (MAP4K3).Synonyms: Germinal center kinase-related protein kinase, MAPK, MAPK/ERK kinase kinase kinase 3, MEKKK 3, Mitogen-activated protein kinase kinase kinase kinase 3, RAB8IPL1
Gene ID 8491, 9606
UniProt Q8IVH8
Research Area Signaling
Pathways MAPK Signaling

Application Details

Product Details anti-MAP4K3 Antibody Target Details MAP4K3 Handling References for anti-MAP4K3 antibody (ABIN360428) Images back to top
Application Notes ELISA: 1/1,000. Western blotting: 1/250 - 1/500. Immunohistochemistry: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-MAP4K3 Antibody Target Details MAP4K3 Application Details References for anti-MAP4K3 antibody (ABIN360428) Images back to top
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

References for anti-MAP4K3 antibody (ABIN360428)

Product Details anti-MAP4K3 Antibody Target Details MAP4K3 Application Details Handling Images back to top
Background publications

Diener, Wang, Chen, Meyer, Keesler, Zukowski, Tan, Yao: "Activation of the c-Jun N-terminal kinase pathway by a novel protein kinase related to human germinal center kinase." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 94, Issue 18, pp. 9687-92, 1997

Images

Product Details anti-MAP4K3 Antibody Target Details MAP4K3 Application Details Handling References for anti-MAP4K3 antibody (ABIN360428) back to top
Supplier Images
 image for anti-Mitogen-Activated Protein Kinase Kinase Kinase Kinase 3 (MAP4K3) (C-Term) antibody (ABIN360428) anti-Mitogen-Activated Protein Kinase Kinase Kinase Kinase 3 (MAP4K3) (C-Term) antibody
 image for anti-Mitogen-Activated Protein Kinase Kinase Kinase Kinase 3 (MAP4K3) (C-Term) antibody (ABIN360428) anti-Mitogen-Activated Protein Kinase Kinase Kinase Kinase 3 (MAP4K3) (C-Term) antibody (Image 2)