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anti-Human MAP4K3 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended MAP4K3 Antibody (supplied by: Log in to see )

Antigen
Mitogen-Activated Protein Kinase Kinase Kinase Kinase 3 (MAP4K3) Antibodies
  • 4833416M01Rik
  • 4833416M07Rik
  • 9530052P13Rik
  • Glk
  • GLK
  • MAPKKKK3
  • MEKKK3
  • MEKKK 3
  • RAB8IPL1
Reactivity
Human
69
23
12
Host
Rabbit
64
12
Clonality
Polyclonal
Conjugate
This MAP4K3 antibody is un-conjugated
6
5
5
5
5
5
Application
Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
69
47
39
32
7
2
Supplier
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Catalog No. ABIN953301
$ 401.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0008917441 ABIN360428 EIA IHC (p) WB Rabbit Ig C-Term Log in to see Polyclonal 1
0.0008917441 ABIN653817 FACS IHC (p) WB Rabbit Ig Log in to see Polyclonal 1
0.0008917441 ABIN658364 FACS IHC (p) WB Rabbit Ig AA 501-529, Center Log in to see Polyclonal
0.0008917441 ABIN1911831 FACS IHC (p) WB Rabbit Internal Region, AA 500-529 Log in to see Polyclonal
0.0008917441 ABIN1811265 FACS IHC (p) WB Rabbit Log in to see Polyclonal
0.0008917441 ABIN1841497 IHC (p) WB Rabbit C-Term Log in to see Polyclonal
0.0008917441 ABIN2963389 FACS IHC (p) WB Rabbit AA 500-529, Internal Region Log in to see Polyclonal

Top referenced anti-MAP4K3 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Similar anti-MAP4K3 Antibodies

Application / Reactivity Human
ELISA 40 Antibodies
Enzyme Immunoassay (EIA) 2 Antibodies
Flow Cytometry (FACS) 27 Antibodies
Immunohistochemistry (IHC) 33 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 8 Antibodies
Western Blotting (WB) 65 Antibodies

General

Antigen Mitogen-Activated Protein Kinase Kinase Kinase Kinase 3 (MAP4K3) Antibodies
Reactivity Human
(69), (23), (12)
Host Rabbit
(64), (12)
Clonality
Polyclonal
Conjugate This MAP4K3 antibody is un-conjugated
(6), (5), (5), (5), (5), (5)
Application Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(69), (47), (39), (32), (7), (2)
Pubmed 1 reference available
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Product Details anti-MAP4K3 Antibody

Target Details MAP4K3 Application Details Handling References for anti-MAP4K3 Antibody (ABIN953301) Images
Specificity This antibody recognizes Human MAP4K3.
Purification Protein A column, followed by peptide affinity purification
Immunogen Recombinant Human MAP4K3 protein
Isotype Ig

Target Details MAP4K3

Product Details anti-MAP4K3 Antibody Application Details Handling References for anti-MAP4K3 Antibody (ABIN953301) Images back to top
Antigen
Alternative Name MAP4K3 (MAP4K3 Antibody Abstract)
Background MAP4K3 encodes a member of the Ste20 family of serine/threonine protein kinases. The protein belongs to the subfamily that consists of members, such as germinal center kinase (GCK), that are characterized by an N-terminal catalytic domain and C-terminal regulatory domain. The kinase activity of the encoded protein can be stimulated by UV radiation and tumor necrosis factor-alpha. The protein specifically activates the c-Jun N-terminal kinase (JNK) signaling pathway. Evidence suggests that it functions upstream of mitogen-activated protein kinase kinase kinase 1 (MEKK1). This gene previously was referred to as RAB8-interacting protein-like 1 (RAB8IPL1), but it has been renamed mitogen-activated protein kinase kinase kinase kinase 3 (MAP4K3).Synonyms: Germinal center kinase-related protein kinase, MAPK, MAPK/ERK kinase kinase kinase 3, MEKKK 3, Mitogen-activated protein kinase kinase kinase kinase 3, RAB8IPL1
Molecular Weight 101316 Da
Gene ID 8491
NCBI Accession NP_003609
Research Area Signaling
Pathways MAPK Signaling

Application Details

Product Details anti-MAP4K3 Antibody Target Details MAP4K3 Handling References for anti-MAP4K3 Antibody (ABIN953301) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-MAP4K3 Antibody Target Details MAP4K3 Application Details References for anti-MAP4K3 Antibody (ABIN953301) Images back to top
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09 % (W/V) Sodium Azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

References for anti-MAP4K3 Antibody (ABIN953301)

Product Details anti-MAP4K3 Antibody Target Details MAP4K3 Application Details Handling Images back to top
Background publications

Yan, Mieulet, Burgess, Findlay, Sully, Procter, Goris, Janssens, Morrice, Lamb: "PP2A T61 epsilon is an inhibitor of MAP4K3 in nutrient signaling to mTOR." in: Molecular cell, Vol. 37, Issue 5, pp. 633-42, 2010

Images

Product Details anti-MAP4K3 Antibody Target Details MAP4K3 Application Details Handling References for anti-MAP4K3 Antibody (ABIN953301) back to top
Supplier Images
Flow Cytometry (FACS) image for anti-MAP4K3 antibody (Mitogen-Activated Protein Kinase Kinase Kinase Kinase 3) (ABIN953301) Flow cytometric analysis of HepG2 cells using MAP4K3 Antibody  (right histogram) comp...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-MAP4K3 antibody (Mitogen-Activated Protein Kinase Kinase Kinase Kinase 3) (ABIN953301) Immunohistochemistry analysis in formalin fixed and paraffin embedded brain tissue re...
Western Blotting (WB) image for anti-MAP4K3 antibody (Mitogen-Activated Protein Kinase Kinase Kinase Kinase 3) (ABIN953301) Western blot analysis of MAP4K3 Antibody  in HepG2 cell line lysates (35ug/lane). MAP...