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anti-Human MAPK10 antibody for Enzyme Immunoassay

Recommended MAPK10 Antibody (supplied by: Log in to see )

Antigen
Mitogen-Activated Protein Kinase 10 (MAPK10) Antibodies
  • ATMPK10
  • C230008H04Rik
  • DKFZp459H0638
  • Jnk3
  • JNK3
  • JNK3A
  • JNK3B1
  • JNK3B2
  • MAPK10
  • MAP kinase 10
  • p54bSAPK
  • p493F12
  • PRKM10
  • SAPb
  • SAPK(beta)
  • SAPK1b
  • SAPKC
  • Serk2
  • zgc:123234
Epitope
N-Term
48
18
8
7
6
4
3
2
2
2
2
1
1
1
Reactivity
Human, Mouse (Murine)
116
53
37
Host
Rabbit
103
22
Clonality
Polyclonal
Conjugate
This MAPK10 antibody is un-conjugated
8
7
6
5
5
5
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
104
78
53
17
11
10
10
3
2
1
1
Supplier
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Catalog No. ABIN359417
$ 390.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0008867729 ABIN359639 EIA IHC (p) WB Rabbit Ig AA 1-30, N-Term Log in to see Polyclonal 1

Top referenced anti-MAPK10 antibody for Enzyme Immunoassay

Similar anti-MAPK10 Antibodies

Application / Reactivity Mouse (Murine) Human
ELISA 24 Antibodies 69 Antibodies
Enzyme Immunoassay (EIA) 2 Antibodies 2 Antibodies
Immunochromatography (IC) 1 Antibodies 3 Antibodies
Immunocytochemistry (ICC) 7 Antibodies 9 Antibodies
Immunofluorescence (IF) 11 Antibodies 17 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 11 Antibodies
Immunohistochemistry (IHC) 16 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 7 Antibodies
Immunoprecipitation (IP) 1 Antibodies
Western Blotting (WB) 40 Antibodies

General

Antigen Mitogen-Activated Protein Kinase 10 (MAPK10) Antibodies
Epitope N-Term
(48), (18), (8), (7), (6), (4), (3), (2), (2), (2), (2), (1), (1), (1)
Reactivity Human, Mouse (Murine)
(116), (53), (37)
Host Rabbit
(103), (22)
Clonality
Polyclonal
Conjugate This MAPK10 antibody is un-conjugated
(8), (7), (6), (5), (5), (5), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(104), (78), (53), (17), (11), (10), (10), (3), (2), (1), (1)
Pubmed 5 references available
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Product Details anti-MAPK10 Antibody

Target Details MAPK10 Application Details Handling References for anti-MAPK10 Antibody (ABIN359417) Images
Specificity This antibody detects MAPK10 at C-term.
Purification Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Immunogen This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human MAPK10.
Isotype Ig

Target Details MAPK10

Product Details anti-MAPK10 Antibody Application Details Handling References for anti-MAPK10 Antibody (ABIN359417) Images back to top
Antigen
Alternative Name MAPK10 (MAPK10 Antibody Abstract)
Background MAPK10 is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This protein is a neuronal-specific form of c-Jun N-terminal kinases (JNKs). Through its phosphorylation and nuclear localization, this kinase plays regulatory roles in the signaling pathways during neuronal apoptosis. Beta-arrestin 2, a receptor-regulated MAP kinase scaffold protein, is found to interact with, and stimulate the phosphorylation of this kinase by MAP kinase kinase 4 (MKK4). Cyclin-dependent kinase 5 can phosphorylate, and inhibit the activity of this kinase, which may be important in preventing neuronal apoptosis.Synonyms: JNK3A, MAP kinase p49 3F12, Mitogen-activated protein kinase 10, PRKM10, Stress-activated protein kinase JNK3, c-Jun N-terminal kinase 3
Molecular Weight 52585 Da
Gene ID 5602, 9606
UniProt P53779
Research Area Cancer
Pathways MAPK Signaling, WNT Signaling, TLR Signaling, Fc-epsilon Receptor Signaling Pathway

Application Details

Product Details anti-MAPK10 Antibody Target Details MAPK10 Handling References for anti-MAPK10 Antibody (ABIN359417) Images back to top
Application Notes ELISA 1: 1,000. Western blot 1: 100 - 1: 500. Immunohistochemistry 1: 50 - 1: 100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-MAPK10 Antibody Target Details MAPK10 Application Details References for anti-MAPK10 Antibody (ABIN359417) Images back to top
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.

References for anti-MAPK10 Antibody (ABIN359417)

Product Details anti-MAPK10 Antibody Target Details MAPK10 Application Details Handling Images back to top
Background publications

Li, Zhang, Takahashi, Ma, Jaffe, Kulkarni, Pant: "Cyclin-dependent kinase 5 prevents neuronal apoptosis by negative regulation of c-Jun N-terminal kinase 3." in: The EMBO journal, Vol. 21, Issue 3, pp. 324-33, 2002

Yoshida, Harada, Nagai, Fukino, Teramoto, Emi: "Head-to-head juxtaposition of Fas-associated phosphatase-1 (FAP-1) and c-Jun NH2-terminal kinase 3 (JNK3) genes: genomic structure and seven polymorphisms of the FAP-1 gene." in: Journal of human genetics, Vol. 47, Issue 11, pp. 614-9, 2002

McDonald, Chow, Miller, Laporte, Field, Lin, Davis, Lefkowitz: "Beta-arrestin 2: a receptor-regulated MAPK scaffold for the activation of JNK3." in: Science (New York, N.Y.), Vol. 290, Issue 5496, pp. 1574-7, 2000

Yang, Kuan, Whitmarsh, Rincón, Zheng, Davis, Rakic, Flavell: "Absence of excitotoxicity-induced apoptosis in the hippocampus of mice lacking the Jnk3 gene." in: Nature, Vol. 389, Issue 6653, pp. 865-70, 1997

Gupta, Barrett, Whitmarsh, Cavanagh, Sluss, Dérijard, Davis: "Selective interaction of JNK protein kinase isoforms with transcription factors." in: The EMBO journal, Vol. 15, Issue 11, pp. 2760-70, 1996

Images

Product Details anti-MAPK10 Antibody Target Details MAPK10 Application Details Handling References for anti-MAPK10 Antibody (ABIN359417) back to top
Supplier Images
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-MAPK10 antibody (Mitogen-Activated Protein Kinase 10) (N-Term) (ABIN359417) Formalin-fixed and paraffin-embedded human cancer tissue (breast carcinoma) reacted w...
Western Blotting (WB) image for anti-MAPK10 antibody (Mitogen-Activated Protein Kinase 10) (N-Term) (ABIN359417) Western blot analysis of anti-MAPK10 Pab in mouse spleen tissue lysate. MAPK10 (arrow...