anti-Frog MAPK3 antibody for Immunohistochemistry

Recommended MAPK3 Antibody (supplied by: Log in to see )

Antigen
Mitogen-Activated Protein Kinase 3 (MAPK3) Antibodies
  • ATMAPK3
  • ATMPK3
  • T6D9.4
  • mitogen-activated protein kinase 3
  • ERK1
  • fi06b09
  • wu:fi06b09
  • zERK1
  • ERK-1
  • ERT2
  • HS44KDAP
  • HUMKER1A
  • P44ERK1
  • P44MAPK
  • PRKM3
  • p44-ERK1
  • p44-MAPK
  • Erk-1
  • Erk1
  • Ert2
  • Esrk1
  • Mnk1
  • Mtap2k
  • Prkm3
  • p44
  • p44erk1
  • p44mapk
  • MAPK1
  • MNK1
  • Tb08.10J17.940
  • mitogen-activated protein kinase 3
  • MAP kinase-like orf; aka CEK1; one of two protein kinase genes similar to S. cerevisiae MAP kinases FUS3 (YBL016W) and KSS1 (YGR040W) involved in pheromone signal transduction
  • mitogen activated protein kinase 3
  • MPK3
  • MAPK3
  • ERK1
  • Mapk3
  • mapk3
  • Tb927.8.3550
  • Tc00.1047053509475.10
Epitope
AA 325-345
49
48
46
39
21
21
19
16
15
14
9
8
5
5
4
4
4
4
3
3
3
3
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Chicken, Dog (Canine), Frog, Human, Mouse (Murine), Rat (Rattus)
485
260
194
35
25
24
23
23
20
20
13
12
11
10
9
7
4
3
3
2
2
2
1
1
1
1
1
Host
Mouse
323
160
20
6
1
Clonality
Monoclonal
Conjugate
This MAPK3 antibody is un-conjugated
26
24
22
16
12
12
6
6
4
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
2
2
2
2
1
1
1
1
1
1
1
1
1
1
Application
Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (IHC), Western Blotting (WB)
401
182
160
101
85
55
55
47
39
16
13
8
7
4
3
2
2
2
1
1
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Catalog No. ABIN967700
Contact our Customer Service for availability and price in your country.
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN967701 IF IP IHC WB Mouse IgG1 AA 325-345 Log in to see MK12 5
1 ABIN967952 IF IP IHC WB Mouse IgG1 AA 325-345 Log in to see MK1 4

General

Antigen Mitogen-Activated Protein Kinase 3 (MAPK3) Antibodies
Epitope AA 325-345
(49), (48), (46), (39), (21), (21), (19), (16), (15), (14), (9), (8), (5), (5), (4), (4), (4), (4), (3), (3), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Chicken, Dog (Canine), Frog, Human, Mouse (Murine), Rat (Rattus)
(485), (260), (194), (35), (25), (24), (23), (23), (20), (20), (13), (12), (11), (10), (9), (7), (4), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1)
Host Mouse
(323), (160), (20), (6), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This MAPK3 antibody is un-conjugated
(26), (24), (22), (16), (12), (12), (6), (6), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (IHC), Western Blotting (WB)
(401), (182), (160), (101), (85), (55), (55), (47), (39), (16), (13), (8), (7), (4), (3), (2), (2), (2), (1), (1)
Pubmed 5 references available
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Product Details anti-MAPK3 Antibody

Target Details MAPK3 Application Details Handling ProductDetails: References for anti-MAPK3 antibody (ABIN967700) Images
Cross-Reactivity Mouse (Murine), Human, Chicken, Dog (Canine), Frog
Characteristics 1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
Purification The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
Immunogen Rat ERK1 aa. 325-345
Clone MK12
Isotype IgG1

Target Details MAPK3

Product Details anti-MAPK3 Antibody Application Details Handling ProductDetails: References for anti-MAPK3 antibody (ABIN967700) Images back to top
Antigen
Alternative Name ERK1 (MAPK3 Antibody Abstract)
Background The family of serine/threonine kinases known as ERKs (extracellular signal regulated kinases) or MAPKs (mitogen-activated protein kinases) is activated after cell stimulation by a variety of hormones and growth factors. Cell stimulation induces a signaling cascade that leads to phosphorylation of MEK (MAPK/ERK kinase) which, in turn, activates ERK via tyrosine and threonine phosphorylation. A myriad of proteins represent the downstream effectors for the active ERK and implicate it in the control of cell proliferation and differentiation, as well as regulation of the cytoskeleton. Activation of ERK is normally transient and cells possess dual specificity phosphatases that are responsible for its down-regulation. Furthermore, multiple studies have shown that elevated ERK activity is associated with some cancers. ERK1 is a 44 kDa member of the ERK family and shares 85% homology with ERK2 (42 kDa).
Molecular Weight 44 kDa
Research Area Stem Cells, Alzheimer's Disease, Signaling, Inflammation
Pathways MAPK Signaling, RTK Signaling, Interferon-gamma Pathway, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Response to Growth Hormone Stimulus, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Protein targeting to Nucleus, Toll-Like Receptors Cascades, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, VEGFR1 Specific Signals

Application Details

Product Details anti-MAPK3 Antibody Target Details MAPK3 Handling ProductDetails: References for anti-MAPK3 antibody (ABIN967700) Images back to top
Comment

Related Products: ABIN968545, ABIN967389

Restrictions For Research Use only

Handling

Product Details anti-MAPK3 Antibody Target Details MAPK3 Application Details ProductDetails: References for anti-MAPK3 antibody (ABIN967700) Images back to top
Format Liquid
Concentration 250 μg/mL
Buffer Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store undiluted at -20°C.

ProductDetails: References for anti-MAPK3 antibody (ABIN967700)

Product Details anti-MAPK3 Antibody Target Details MAPK3 Application Details Handling Images back to top
Product cited in:

Nowak: "Protein kinase C-alpha and ERK1/2 mediate mitochondrial dysfunction, decreases in active Na+ transport, and cisplatin-induced apoptosis in renal cells." in: The Journal of biological chemistry, Vol. 277, Issue 45, pp. 43377-88, 2002

Aguirre-Ghiso, Liu, Mignatti, Kovalski, Ossowski: "Urokinase receptor and fibronectin regulate the ERK(MAPK) to p38(MAPK) activity ratios that determine carcinoma cell proliferation or dormancy in vivo." in: Molecular biology of the cell, Vol. 12, Issue 4, pp. 863-79, 2001

Ackerley, Grierson, Brownlees, Thornhill, Anderton, Leigh, Shaw, Miller: "Glutamate slows axonal transport of neurofilaments in transfected neurons." in: The Journal of cell biology, Vol. 150, Issue 1, pp. 165-76, 2000

Wan, Huang: "Analysis of the Gs/mitogen-activated protein kinase pathway in mutant S49 cells." in: The Journal of biological chemistry, Vol. 273, Issue 23, pp. 14533-7, 1998

Reszka, Seger, Diltz, Krebs, Fischer: "Association of mitogen-activated protein kinase with the microtubule cytoskeleton." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 92, Issue 19, pp. 8881-5, 1995

Images

Product Details anti-MAPK3 Antibody Target Details MAPK3 Application Details Handling ProductDetails: References for anti-MAPK3 antibody (ABIN967700) back to top
Supplier Images
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Mitogen-Activated Protein Kinase 3 (MAPK3) (AA 325-345) antibody (ABIN967700) Immunohistochemical staining of ERK1 in pyrimidal cells from the rat cortex: formalin...
Western Blotting (WB) image for anti-Mitogen-Activated Protein Kinase 3 (MAPK3) (AA 325-345) antibody (ABIN967700) Western blot analysis of ERK1 on a rat cerebrum lysate. Lane 1: 1:4000, lane 2: 1:800...
Immunofluorescence (IF) image for anti-Mitogen-Activated Protein Kinase 3 (MAPK3) (AA 325-345) antibody (ABIN967700) Immunofluorescence staining of human fibroblasts.