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anti-Human MAPK9 antibody for Immunoprecipitation

Recommended MAPK9 Antibody (supplied by: Log in to see )

Antigen
Mitogen-Activated Protein Kinase 9 (MAPK9) Antibodies
  • AI851083
  • JNK-55
  • JNK2
  • JNK2-ALPHA1
  • JNK2A
  • JNK2ALPHA
  • JNK2B
  • JNK2BETA
  • MAPK9
  • MAP kinase 9
  • p54a
  • p54aSAPK
  • Prkm9
  • PRKM9
  • SAPK
  • SAPK1a
Epitope
AA 1-424
23
15
15
12
12
10
9
7
7
6
6
5
5
4
3
2
1
1
1
1
1
1
1
1
1
Reactivity
Human
149
58
43
13
6
4
2
2
1
1
1
Host
Rabbit
100
37
19
1
1
Clonality
Polyclonal
Conjugate
This MAPK9 antibody is un-conjugated
5
4
3
3
3
3
Minimum Detection Limit
0.00245 ng/well
Application
Immunoprecipitation (IP), ELISA
143
78
55
32
20
10
7
6
3
1
1
1
1
Supplier
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Catalog No. ABIN1997379
$ 218.90
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.00089235755 ABIN1997369 IP ELISA WB Mouse IgG2b AA 1-424 Log in to see 3C3C12E5
0.00089235755 ABIN1873633 ICC IP IHC WB Rabbit IgG Log in to see Polyclonal
0.00089235755 ABIN1821866 ICC IP IHC WB Rabbit IgG Thr183 Log in to see Polyclonal
0.00089235755 ABIN1997375 IF IP IHC (p) ELISA WB Rabbit IgG AA 1-424 Log in to see 11
0.00089235755 ABIN2404166 ICC IF IP IHC WB Rabbit IgG Log in to see Polyclonal
0.00089235755 ABIN2698433 IC IF IP IHC WB Rabbit IgG Log in to see Polyclonal
0.00089235755 ABIN2293918 IP WB Rabbit IgG Log in to see 5i115
0.00089235755 ABIN2959788 IP WB Mouse IgG2 full length Log in to see 2G12
0.00089235755 ABIN2989604 ICC IF IP IHC WB Rabbit IgG Log in to see Polyclonal
0.00089235755 ABIN2682325 IP ELISA Rabbit Log in to see Polyclonal

Similar anti-MAPK9 Antibodies

Application / Reactivity Human
Dot Blot (DB) 1 Antibodies
ELISA 73 Antibodies
ELISA (Capture) 1 Antibodies
Enzyme Immunoassay (EIA) 7 Antibodies
Immunochromatography (IC) 1 Antibodies
Immunocytochemistry (ICC) 9 Antibodies
Immunofluorescence (IF) 23 Antibodies
Immunohistochemistry (IHC) 51 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 3 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 33 Antibodies
Immunoprecipitation (IP) 11 Antibodies
Proximity Ligation Assay (PLA) 1 Antibodies
RNA Interference (RNAi) 1 Antibodies
Western Blotting (WB) 138 Antibodies

General

Antigen Mitogen-Activated Protein Kinase 9 (MAPK9) Antibodies
Epitope AA 1-424
(23), (15), (15), (12), (12), (10), (9), (7), (7), (6), (6), (5), (5), (4), (3), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human
(149), (58), (43), (13), (6), (4), (2), (2), (1), (1), (1)
Host Rabbit
(100), (37), (19), (1), (1)
Clonality
Polyclonal
Conjugate This MAPK9 antibody is un-conjugated
(5), (4), (3), (3), (3), (3)
Minimum Detection Limit 0.00245 ng/well
Application Immunoprecipitation (IP), ELISA
(143), (78), (55), (32), (20), (10), (7), (6), (3), (1), (1), (1), (1)
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Product Details anti-MAPK9 Antibody

Target Details MAPK9 Application Details Handling Images
Specificity Human JNK2 / MAPK9
Characteristics Produced in rabbits immunized with purified, recombinant Human JNK2 / MAPK9 (rh JNK2 / MAPK9, NP_002743.3, Met 1-Arg 424). JNK2 / MAPK9 specific IgG was purified by Human JNK2 / MAPK9 affinity chromatography.
Purification Affinity Purified
Sterility 0.2 μm filtered
Isotype IgG

Target Details MAPK9

Product Details anti-MAPK9 Antibody Application Details Handling Images back to top
Antigen
Alternative Name MAPK9 (MAPK9 Antibody Abstract)
Background Mitogen-activated protein kinase 9 (MAPK9), also well known as c-Jun N-terminal kinase (JNK2), is a member of MAP kinase subfamily belonging to the protein kinase superfamily. MAPK9 responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, such as c-Jun and ATF2. The crystal structure of human JNK2 complexed with an indazole inhibitor by applying a high-throughput protein engineering and surface-site mutagenesis approach. A novel conformation of the activation loop is observed, which is not compatible with its phosphorylation by upstream kinases. This activation inhibitory conformation of JNK2 is stabilized by the MAP kinase insert that interacts with the activation loop in an induced-fit manner. It suggest that the MAP kinase insert of JNK2 plays a role in the regulation of JNK2 activation, possibly by interacting with intracellular binding partners. JNK2 deficiency leads to reduced c-Jun degradation, thereby augmenting c-Jun levels and cellular proliferation, and suggests that JNK2 is a negative regulator of cellular proliferation in multiple cell types. JNK2 prevents replicative stress by coordinating cell cycle progression and DNA damage repair mechanisms. JNK2 blocks the ubiquitination of tumor suppressor p53, and thus increases the stability of p53 in nonstressed cells. JNK2 negatively regulates antigen-specific CD8+ T cell expansion and effector function, and thus selectively blocking JNK2 in CD8+ T cells may potentially enhance anti-tumor immune response. Lack of JNK2 expression was associated with higher tumor aneuploidy and reduced DNA damage response. Additionally,the JNK2 protein could be a novel therapeutic target in dry eye disease, and may provide a novel target for prevention of vascular disease and atherosclerosis.
NCBI Accession NP_002743.3
Pathways MAPK Signaling, WNT Signaling, TCR Signaling, TLR Signaling, Fc-epsilon Receptor Signaling Pathway

Application Details

Product Details anti-MAPK9 Antibody Target Details MAPK9 Handling Images back to top
Application Notes ELISA ELISA: 0.1-0.2 μg/mL This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect Human MAPK9 . The detection limit for Human MAPK9 is approximately 0.00245 ng/well.
Restrictions For Research Use only

Handling

Product Details anti-MAPK9 Antibody Target Details MAPK9 Application Details Images back to top
Buffer PBS with 5% trehalose
Preservative Without preservative
Handling Advice Avoid repeated freeze-thaw cycles.
Storage 4 °C/-20 °C/-80 °C
Storage Comment This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -70°C. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly.
Expiry Date 12 months

Images

Product Details anti-MAPK9 Antibody Target Details MAPK9 Application Details Handling back to top
Supplier Images
Immunoprecipitation (IP) image for anti-MAPK9 antibody (Mitogen-Activated Protein Kinase 9) (AA 1-424) (ABIN1997379) anti-Mitogen-Activated Protein Kinase 9 (MAPK9) (AA 1-424) antibody