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Browse our MAPKAP Kinase 2 Proteins (MAPKAPK2)

Full name:
Mitogen-Activated Protein Kinase-Activated Protein Kinase 2 Proteins (MAPKAPK2)
On www.antibodies-online.com are 15 Mitogen-Activated Protein Kinase-Activated Protein Kinase 2 (MAPKAPK2) Proteins from 8 different suppliers available. Additionally we are shipping MAPKAP Kinase 2 Antibodies (236) and MAPKAP Kinase 2 Kits (12) and many more products for this protein. A total of 276 MAPKAP Kinase 2 products are currently listed.
Synonyms:
AA960234, MAPKAP-K2, MAPKAPK2, MGC78852, MK-2, MK2, Rps6kc1, wu:fb30e10, wu:fc56c10, wu:fi03a01
list all proteins Gene Name GeneID UniProt
MAPKAPK2 17164 P49138
MAPKAPK2 9261 P49137
Rat MAPKAPK2 MAPKAPK2 289014  

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MAPKAP Kinase 2 Proteins (MAPKAPK2) by Origin

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More Proteins for MAPKAP Kinase 2 Interaction Partners

Zebrafish Mitogen-Activated Protein Kinase-Activated Protein Kinase 2 (MAPKAPK2) interaction partners

  1. a p38 MAPKAPK2 kinase cascade modulates the activity of F-actin at the yolk cell margin circumference allowing the gradual closure of the blastopore as epiboly progresses

Mouse (Murine) Mitogen-Activated Protein Kinase-Activated Protein Kinase 2 (MAPKAPK2) interaction partners

  1. MK2 (show KCNA2 Proteins)-activating peptide (MK2 (show KCNA2 Proteins)-AP) blocks the effects of anthrax lethal toxin on endothelial barriers in cultured cells and reduces pulmonary vascular leak in rats.

  2. MK2 (show KCNA2 Proteins) regulates postnatal arteriogenesis by controlling vascular recruitment of monocytes/macrophages in dual manner: regulation of endothelial MCP-1 (show CPT1B Proteins) expression in response to hemodynamic and inflammatory forces as well as MCP-1 (show CPT1B Proteins) dependent monocyte migration

  3. these data suggest there is a sexual dimorphism in MK2 (show KCNA2 Proteins) signaling of osteoclast progenitor cell subpopulations.

  4. Loss of MK2 (show KCNA2 Proteins) effectively blocks bone resorption and prevents the development of postmenopausal bone loss.

  5. This study showed that cmpd28, a Mapkapk2/3 inhibitor, represents a potentially new approach to type 2 diabetes therapy.

  6. Deficiency of MK2 (show KCNA2 Proteins) prevents adverse remodelling and promotes endothelial healing of the arterial wall after injury.

  7. high-fat diet-fed MK2 (show KCNA2 Proteins)-/- mice display decreased glucose tolerance and increased insulin (show INS Proteins) resistance compared to controls. Decreased adipose tissue expression of GLUT4 (show SLC2A4 Proteins) might contribute to this phenotype.

  8. Show a low dose of tumor necrosis factor (TNF (show TNF Proteins)) causes hyperacute mortality via an oxidative stress driven mechanism in MK2 (show KCNA2 Proteins)-deficient mice. In addition, MK2 (show KCNA2 Proteins)-deficient mice were found to be more sensitive to cecal ligation and puncture-induced sepsis.

  9. a key role of MK2 (show KCNA2 Proteins) and FasR in the regulation and limitation of the immune response in the CNS

  10. These data suggest that MK2 (show KCNA2 Proteins) is a key downstream effector of p38 (show CRK Proteins) that can modulate pemphigus vulgaris (show DSG3 Proteins) autoantibody pathogenicity.

Human Mitogen-Activated Protein Kinase-Activated Protein Kinase 2 (MAPKAPK2) interaction partners

  1. MK2 (show KCNA2 Proteins) overexpression is associated with primary liver tumors.

  2. CEP131 is the key regulatory target of MK2 (show KCNA2 Proteins) and 14-3-3 (show YWHAQ Proteins) in centriolar satellite remodeling.

  3. mTOR (show FRAP1 Proteins) controls the senescence-associated secretory phenotype by differentially regulating the translation of the MK2 (show KCNA2 Proteins) (also known as MAPKAPK2).

  4. analysis of signaling cooperation between p38-MAPK (show MAPK14 Proteins)/MAPKAP-2/Hsp27 (show HSPB1 Proteins) and intracellular calcium release in AA-induced HBEC apoptosis

  5. findings reveal MK2 (show KCNA2 Proteins)/MK3 (show KCNA3 Proteins) as crucial stress-responsive kinases that promote autophagy through Beclin 1 (show BECN1 Proteins) S90 phosphorylation

  6. The protein expression of both HMGB1 (show HMGB1 Proteins) and MAPKAPK2 were increased in KLM1-R cells.

  7. Data indicate the binding mode and molecular mechanism of action of MAPK-activated protein kinase-2 (MK2) and inhibitors.

  8. Treatment with MK2 (show KCNA2 Proteins) or p38 (show CRK Proteins) inhibitors blocked human papillomavirus genome amplification, identifying the p38 (show CRK Proteins)/MK2 (show KCNA2 Proteins) pathway as a key regulator of the human papillomavirus life cycle.

  9. a key role of MK2 (show KCNA2 Proteins) and FasR in the regulation and limitation of the immune response in the CNS

  10. IscU (show ISCU Proteins) is a new substrate of MK2 (show KCNA2 Proteins) both in Drosophila cells and in human cells

MAPKAP Kinase 2 (MAPKAPK2) Protein Profile

Protein Summary

This gene encodes a member of the Ser/Thr protein kinase family. This kinase is regulated through direct phosphorylation by p38 MAP kinase. In conjunction with p38 MAP kinase, this kinase is known to be involved in many cellular processes including stress and inflammatory responses, nuclear export, gene expression regulation and cell proliferation. Heat shock protein HSP27 was shown to be one of the substrates of this kinase in vivo. Two transcript variants encoding two different isoforms have been found for this gene.

Alternative names and synonyms associated with MAPKAP Kinase 2 (MAPKAPK2)

  • mitogen-activated protein kinase-activated protein kinase 2a (mapkapk2a)
  • mitogen-activated protein kinase-activated protein kinase 2 (mapkapk2)
  • mitogen-activated protein kinase-activated protein kinase 2 (MAPKAPK2)
  • MAP kinase-activated protein kinase 2 (Mapkapk2)
  • mitogen-activated protein kinase-activated protein kinase 2 (Mapkapk2)
  • AA960234 protein
  • MAPKAP-K2 protein
  • MAPKAPK2 protein
  • MGC78852 protein
  • MK-2 protein
  • MK2 protein
  • Rps6kc1 protein
  • wu:fb30e10 protein
  • wu:fc56c10 protein
  • wu:fi03a01 protein

Protein level used designations for MAPKAPK2

MAP kinase-activated protein kinase 2 , bbp , betty boop , mitogen-activated protein kinase-activated protein kinase 2 , MAPK-activated protein kinase 2 , MAPKAP kinase 2 , MAPKAPK-2 , map kinase activated protein kinase-2

GENE ID SPECIES
327321 Danio rerio
432084 Xenopus laevis
695044 Macaca mulatta
744091 Pan troglodytes
100579643 Nomascus leucogenys
17164 Mus musculus
9261 Homo sapiens
490263 Canis lupus familiaris
788091 Bos taurus
289014 Rattus norvegicus
419847 Gallus gallus
100009438 Oryctolagus cuniculus
100715906 Cavia porcellus
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