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Browse our anti-MAPKAP Kinase 5 (MAPKAPK5) Antibodies

Full name:
anti-Mitogen-Activated Protein Kinase-Activated Protein Kinase 5 Antibodies (MAPKAPK5)
On www.antibodies-online.com are 161 Mitogen-Activated Protein Kinase-Activated Protein Kinase 5 (MAPKAPK5) Antibodies from 17 different suppliers available. Additionally we are shipping MAPKAP Kinase 5 Proteins (9) and MAPKAP Kinase 5 Kits (5) and many more products for this protein. A total of 189 MAPKAP Kinase 5 products are currently listed.
Synonyms:
MAPKAP-K5, MAPKAPK5, MK-5, MK5, PRAK
list all antibodies Gene Name GeneID UniProt
MAPKAPK5 17165 O54992
MAPKAPK5 8550 Q8IW41
MAPKAPK5 498183  

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Most Popular Reactivities for anti-MAPKAP Kinase 5 (MAPKAPK5) Antibodies

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anti-Mouse (Murine) MAPKAP Kinase 5 Antibodies:

anti-Human MAPKAP Kinase 5 Antibodies:

anti-Rat (Rattus) MAPKAP Kinase 5 Antibodies:

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Top referenced anti-MAPKAP Kinase 5 Antibodies

  1. Human Polyclonal MAPKAP Kinase 5 Primary Antibody for EIA, WB - ABIN359410 : Sudo, Maruyama, Osada: p62 functions as a p38 MAP kinase regulator. in Biochemical and biophysical research communications 2000 (PubMed)
    Show all 3 references for ABIN359410

  2. Human Monoclonal MAPKAP Kinase 5 Primary Antibody for IHC, ELISA - ABIN969362 : Paliga, Natale, Watson: p38 mitogen-activated protein kinase (MAPK) first regulates filamentous actin at the 8-16-cell stage during preimplantation development. in Biology of the cell / under the auspices of the European Cell Biology Organization 2005 (PubMed)
    Show all 3 references for ABIN969362

  3. Human Polyclonal MAPKAP Kinase 5 Primary Antibody for EIA, IHC (p) - ABIN358154 : New, Jiang, Zhao, Liu, Zhu, Flood, Kato, Parry, Han: PRAK, a novel protein kinase regulated by the p38 MAP kinase. in The EMBO journal 1998 (PubMed)
    Show all 2 references for ABIN358154

  4. Human Polyclonal MAPKAP Kinase 5 Primary Antibody for IHC (p), WB - ABIN389587 : Daily, Monks, Leggas, Moscow: Abrogation of microcystin cytotoxicity by MAP kinase inhibitors and N-acetyl cysteine is confounded by OATPIB1 uptake activity inhibition. in Toxicon : official journal of the International Society on Toxinology 2010 (PubMed)

More Antibodies against MAPKAP Kinase 5 Interaction Partners

Mouse (Murine) Mitogen-Activated Protein Kinase-Activated Protein Kinase 5 (MAPKAPK5) interaction partners

  1. An alternative targeting strategy of MK5/PRAK (termed MK5/PRAK-Deltaex6) increased neither tumor incidence in the one step skin carcinogenesis model, nor Ras-induced transformation in primary cells.

  2. MK5 positively regulates Rag transcription via phosphorylation of Foxo1 (show FOXO1 Antibodies) in developing B cells.

  3. observations have demonstrated that PRAK is not required for either the rottlerin-mediated anti-chlamydial activity or rottlerin inhibition of sphingolipid trafficking, suggesting rottlerin may achieve its inhibitory role by targeting other host factors

  4. Results suggest that PRAK may function as a tumor suppressor in multiple types of cancers.

  5. the regulation of neuronal morphogenesis is proposed as the first physiological function of the ERK3 (show RYK Antibodies)/MK5 signaling module

  6. It was shown that the tumor-suppressing and tumor-promoting functions of the p38 (show CRK Antibodies)-PRAK pathway are temporally and spatially separated during cancer development in vivo, relying on the stimulus, and the tissue type and the stage of cancer development.

  7. Rheb (show RHEB Antibodies) inactivation by PRAK-mediated phosphorylation is essential for energy-depletion-induced suppression of mTORC1

  8. MK5 co-immunoprecipitated ERK3 (show RYK Antibodies), but not ERK4 (show MAPK4 Antibodies) or p38 alpha (show MAPK14 Antibodies), in control and hypertrophying hearts (MK5).

  9. Both binding and activation of p38 mitogen-activated protein kinase (show MAPK14 Antibodies) (MAPK (show MAPK1 Antibodies)) play essential roles in regulation of the nucleocytoplasmic distribution of MAPK-activated protein kinase 5 by cellular stress.

  10. Data suggest that the differences between the phenotypes of MK5- and MK2 (show KCNA2 Antibodies)-deficient mice result from clearly different functional properties of both enzymes.

Human Mitogen-Activated Protein Kinase-Activated Protein Kinase 5 (MAPKAPK5) interaction partners

  1. Plasma MAPKAPK5 protein was found to positively associate with the 10-year change in paired associates learning assessment in asymptomatic older twins.

  2. Data highlight that DJ-1 (show PARK7 Antibodies) is the downstream interacting target for PRAK, and in response to oxidative stress PRAK may exert a cytoprotective effect by facilitating DJ-1 (show PARK7 Antibodies) to sequester Daxx (show DAXX Antibodies) in the nucleus, thus preventing cell death.

  3. Data indicate that the structurally most flexible regions during molecular dynamics (MD) simulations of the native mitogen-activated protein kinase (show MAPK1 Antibodies)-activated protein kinase (show CDK7 Antibodies) MK5 model were the loop regions.

  4. Studies with specific phosphoantibodies indicate that MK5 phosphorylates Hsp40/DnaJB1 (show DNAJB1 Antibodies) in vivo at Ser (show SIGLEC1 Antibodies)-149 or/and Ser (show SIGLEC1 Antibodies)-151 and Ser (show SIGLEC1 Antibodies)-171 in the C-terminal domain of Hsp40/DnaJB1 (show DNAJB1 Antibodies).

  5. study shows Tip60 (show KAT5 Antibodies) plays an essential role in oncogenic ras-induced senescence; revealed a cascade of posttranslational modifications involving p38 (show CRK Antibodies), Tip60 (show KAT5 Antibodies) and PRAK, 3 proteins essential for ras-induced senescence; these modifications are critical for prosenescent function of Tip60 (show KAT5 Antibodies) and PRAK

  6. these results firstly demonstrate that MK5 is degraded in response to doxorubicin and negatively regulates doxorubicin-induced apoptosis, providing novel insights into the molecular mechanism of doxorubicin resistance in hepatoma cells.

  7. IGF2BP1 (show IGF2BP1 Antibodies) promotes the velocity and directionality of tumor-derived cell migration by determining the cytoplasmic fate of two novel target mRNAs: MAPK4 (show MAPK4 Antibodies) and PTEN (show PTEN Antibodies)

  8. Rheb (show RHEB Antibodies) inactivation by PRAK-mediated phosphorylation is essential for energy-depletion-induced suppression of mTORC1

  9. Activation loop phosphorylation of ERK3/ERK4 (show MAPK4 Antibodies) by group I p21 (show CDKN1A Antibodies)-activated kinases (PAKs) defines a novel PAK-ERK3 (show MAPK4 Antibodies)/4-MAPK-activated protein kinase 5 signaling pathway.

  10. This review discusses the different characteristics of regulating the activity and subcellular localization of MK5 and RSK1 (show RPS6KA1 Antibodies) by PKA and the functional implications of these interactions.

MAPKAP Kinase 5 (MAPKAPK5) Antigen Profile

Antigen Summary

The protein encoded by this gene is a tumor suppressor and member of the serine/threonine kinase family. In response to cellular stress and proinflammatory cytokines, this kinase is activated through its phosphorylation by MAP kinases including MAPK1/ERK, MAPK14/p38-alpha, and MAPK11/p38-beta. The encoded protein is found in the nucleus but translocates to the cytoplasm upon phosphorylation and activation. This kinase phosphorylates heat shock protein HSP27 at its physiologically relevant sites. Two alternately spliced transcript variants of this gene encoding distinct isoforms have been reported.

Alternative names and synonyms associated with MAPKAP Kinase 5 (MAPKAPK5)

  • mitogen-activated protein kinase-activated protein kinase 5 (MAPKAPK5) antibody
  • mitogen-activated protein kinase-activated protein kinase 5 (mapkapk5) antibody
  • MAP kinase-activated protein kinase 5 (Mapkapk5) antibody
  • mitogen-activated protein kinase-activated protein kinase 5 (Mapkapk5) antibody
  • MAPKAP-K5 antibody
  • MAPKAPK5 antibody
  • MK-5 antibody
  • MK5 antibody
  • PRAK antibody

Protein level used designations for MAPKAPK5

mitogen-activated protein kinase-activated protein kinase 5 , MAP kinase-activated protein kinase 5 , MAP kinase-activated protein kinase 5-like , MAPK-activated protein kinase 5 , MAPKAP kinase 5 , MAPKAPK-5 , p38-regulated/activated protein kinase

GENE ID SPECIES
100057579 Equus caballus
738233 Pan troglodytes
100017664 Monodelphis domestica
100230432 Taeniopygia guttata
100412389 Callithrix jacchus
100434701 Pongo abelii
100482977 Ailuropoda melanoleuca
100548508 Meleagris gallopavo
100553264 Anolis carolinensis
100582875 Nomascus leucogenys
17165 Mus musculus
8550 Homo sapiens
498183 Rattus norvegicus
373929 Gallus gallus
477480 Canis lupus familiaris
100153404 Sus scrofa
535625 Bos taurus
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