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anti-Human MAPT antibody for Immunohistochemistry (Frozen Sections)

Recommended MAPT Antibody (supplied by: Log in to see )

Antigen
Microtubule-Associated Protein tau (MAPT) Antibodies
  • AI413597
  • AI426939
  • AI551861
  • AW045860
  • AW457082
  • CK1epsilon
  • CKIe
  • DDPAC
  • FTDP-17
  • KC1epsilon
  • MAPT
  • MAPTL
  • MSTD
  • Mtapt
  • MTBT1
  • MTBT2
  • PHF-tau
  • PPND
  • pTau
  • RNPTAU
  • tau
  • Tau
  • TAU
  • xtp
Reactivity
Human
966
467
445
76
21
19
17
12
9
5
4
4
3
3
3
3
2
1
1
1
1
1
1
Host
Mouse
921
97
9
9
Clonality
Monoclonal
Conjugate
This MAPT antibody is un-conjugated
23
8
8
5
4
4
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
861
351
309
103
69
69
37
16
14
12
12
12
11
7
4
3
2
1
1
Supplier
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Catalog No. ABIN110964
$ 577.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.00088051456 ABIN1869091 ICC IHC (fro) IHC (p) ELISA WB Rabbit IgG AA 130-386 Log in to see Polyclonal
0.00088051456 ABIN609091 IHC (fro) IHC (p) WB Rabbit IgG AA 240-450 Log in to see Polyclonal
0.00088051456 ABIN1108150 EIA IHC (fro) WB Rabbit N-Term Log in to see Polyclonal
0.00088051456 ABIN444560 IHC (fro) IHC (p) Rabbit IgG Log in to see Polyclonal

Similar anti-MAPT Antibodies

Application / Reactivity Human
Cellular Assay (CA) 12 Antibodies
Dot Blot (DB) 69 Antibodies
ELISA 338 Antibodies
Enzyme Immunoassay (EIA) 14 Antibodies
Flow Cytometry (FACS) 4 Antibodies
Immunoassay (IA) 12 Antibodies
Immunochromatography (IC) 4 Antibodies
Immunocytochemistry (ICC) 17 Antibodies
Immunofluorescence (IF) 91 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 11 Antibodies
Immunohistochemistry (IHC) 299 Antibodies
Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp)) 1 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 5 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 68 Antibodies
Immunoprecipitation (IP) 18 Antibodies
Immunostaining (ISt) 12 Antibodies
Western Blotting (WB) 811 Antibodies

General

Antigen Microtubule-Associated Protein tau (MAPT) Antibodies
Reactivity Human
(966), (467), (445), (76), (21), (19), (17), (12), (9), (5), (4), (4), (3), (3), (3), (3), (2), (1), (1), (1), (1), (1), (1)
Host Mouse
(921), (97), (9), (9)
Clonality (Clone)
Monoclonal   ( )
Conjugate This MAPT antibody is un-conjugated
(23), (8), (8), (5), (4), (4), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(861), (351), (309), (103), (69), (69), (37), (16), (14), (12), (12), (12), (11), (7), (4), (3), (2), (1), (1)
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Product Details anti-MAPT Antibody

Target Details MAPT Application Details Handling Images
Specificity This antibody reacts with Tau in both the phosphorylated and non-phosphorylated form. It recognises an epitope between amino acids 95 - 108 of bovine Tau. It does not react with other Microtubule associated proteins or tubulin.
Purification Ascites
Immunogen Bovine microtubule associated proteins.
Clone 4F1
Isotype IgG1

Target Details MAPT

Product Details anti-MAPT Antibody Application Details Handling Images back to top
Antigen
Alternative Name MAPT / tau (MAPT Antibody Abstract)
Background Tau is a neuronal microtubule associated protein found predominantly on axons. The function of Tau is to promote tubulin polymerisation and stabilise microtubules, but it also serves to link certain signalling pathways to the cytoskeleton. Tau, in its hyperphosphorylated form, is the major component of paired helical filaments (PHF) and neurofibrillary lesions in Alzheimer's disease (AD) brain. Hyperphosphorylation impairs the microtubule binding function of Tau, resulting in the destabilisation of microtubules in AD brains, ultimately leading to the degeneration of the affected neurons. Hyperphosphorylated tau is also found in a range of other central nervous system disorders. Numerous serine/threonine kinases, including GSK3 beta, PKA, Cdk5, and casein kinase II can phosphorylate Tau.Synonyms: MAPTL, MTBT1, Microtubule-associated protein tau, Neurofibrillary tangle protein, PHF-tau, Paired helical filament-tau
Gene ID 281296
NCBI Accession NP_776531
UniProt P29172
Research Area Cytoskeleton
Pathways MAPK Signaling, Microtubule Dynamics

Application Details

Product Details anti-MAPT Antibody Target Details MAPT Handling Images back to top
Application Notes Western Blot: 1/250 - 1/1000. Immunohistochemistry on frozen and paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-MAPT Antibody Target Details MAPT Application Details Images back to top
Format Liquid
Concentration 1.0 mg/mL
Buffer PBS, pH 7.2 containing 0.09 % Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage -20 °C
Storage Comment Store the antibody at -20 °C. Can be shipped at 2 - 8 °C.