anti-Human MAPT antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended MAPT Antibody (supplied by: Log in to see )

Antigen
Microtubule-Associated Protein tau (MAPT) Antibodies
  • tau
  • xtp
  • MAPT
  • AI426939
  • AI551861
  • AW457082
  • CK1epsilon
  • CKIe
  • KC1epsilon
  • DDPAC
  • FTDP-17
  • MAPTL
  • MSTD
  • MTBT1
  • MTBT2
  • PPND
  • TAU
  • AI413597
  • AW045860
  • Mtapt
  • Tau
  • PHF-tau
  • RNPTAU
  • pTau
  • microtubule-associated protein tau
  • Microtubule-associated protein tau
  • casein kinase 1, epsilon
  • mapt
  • MAPT
  • AaeL_AAEL015538
  • AaeL_AAEL012206
  • CpipJ_CPIJ013260
  • tau
  • Csnk1e
  • Mapt
Epitope
Ser404
66
50
44
40
40
40
38
38
32
32
31
30
23
21
17
17
16
16
16
13
13
12
11
11
10
9
8
8
8
8
7
7
6
6
6
6
6
6
5
5
4
4
4
4
4
3
3
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
1065
633
614
133
47
44
43
34
25
17
12
10
4
4
4
3
3
3
3
2
2
2
2
2
1
1
1
1
Host
Rabbit
963
142
13
7
Clonality
Polyclonal
Conjugate
This MAPT antibody is un-conjugated
25
10
10
7
4
4
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
998
345
308
151
96
60
56
54
14
13
12
12
12
9
8
5
4
1
Supplier
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Catalog No. ABIN615572
$ 500.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
11.569705 ABIN213794 IHC (p) WB Rabbit pSer202 Log in to see Polyclonal
11.569705 ABIN615582 IHC (p) WB Rabbit Ser422 Log in to see Polyclonal
11.569705 ABIN121838 EIA IHC (p) WB Rabbit Log in to see Polyclonal
11.569705 ABIN953316 IF IHC (p) WB Chicken Ig Log in to see Polyclonal
1 ABIN388782 IF IHC (p) WB Rabbit Ig AA 677-707, C-Term Log in to see Polyclonal 4
1 ABIN388191 IHC (p) WB Rabbit Ig AA 699-728, Ser720 Log in to see Polyclonal 1
1 ABIN196810 IF IHC (p) WB Rabbit pSer404 Log in to see Polyclonal 5
1 ABIN2854882 IHC (p) WB Rabbit IgG Center Log in to see Polyclonal
1 ABIN196790 IHC (p) WB Rabbit pSer396 Log in to see Polyclonal 5
1 ABIN196800 IHC (p) WB Rabbit pThr181 Log in to see Polyclonal 4
1 ABIN196806 IHC (p) WB Rabbit pThr231 Log in to see Polyclonal 5
1 ABIN197266 IF IHC (p) WB Rabbit Thr231 Log in to see Polyclonal 5
1 ABIN1108149 IHC (p) WB Mouse IgG1 Log in to see TAU-93 1
1 ABIN5552071 EIA IHC (p) WB Rabbit Ig Fraction C-Term Log in to see Polyclonal
1 ABIN197256 IHC (p) WB Rabbit Ser396 Log in to see Polyclonal 3
1 ABIN3043669 IHC (p) WB Mouse IgG1 Log in to see TAU-2 4
1 ABIN257610 ICC IF IHC (p) IHC WB Rabbit pSer262 Log in to see Polyclonal
1 ABIN257611 IHC (p) IHC WB Rabbit pSer396 Log in to see Polyclonal
1 ABIN257613 IHC (p) IHC WB Rabbit pThr181 Log in to see Polyclonal
1 ABIN680048 IF (p) IHC (p) WB Rabbit IgG AA 210-250, pThr548 Log in to see Polyclonal 1

General

Antigen Microtubule-Associated Protein tau (MAPT) Antibodies
Epitope Ser404
(66), (50), (44), (40), (40), (40), (38), (38), (32), (32), (31), (30), (23), (21), (17), (17), (16), (16), (16), (13), (13), (12), (11), (11), (10), (9), (8), (8), (8), (8), (7), (7), (6), (6), (6), (6), (6), (6), (5), (5), (4), (4), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(1065), (633), (614), (133), (47), (44), (43), (34), (25), (17), (12), (10), (4), (4), (4), (3), (3), (3), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1)
Host Rabbit
(963), (142), (13), (7)
Clonality
Polyclonal
Conjugate This MAPT antibody is un-conjugated
(25), (10), (10), (7), (4), (4), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(998), (345), (308), (151), (96), (60), (56), (54), (14), (13), (12), (12), (12), (9), (8), (5), (4), (1)
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Product Details anti-MAPT Antibody

Target Details MAPT Application Details Handling Images
Sequence D-T-SP-P-R
Specificity This antibody detects endogenous levels of total Tau protein.
Cross-Reactivity (Details) Species reactivity (expected):Mouse, ratSpecies reactivity (tested):Human
Purification Immunoaffinity chromatography
Immunogen Synthesized non-phosphopeptide derived from human Tau around the phosphorylation site of serine 404
Isotype IgG

Target Details MAPT

Product Details anti-MAPT Antibody Application Details Handling Images back to top
Antigen
Alternative Name MAPT / tau (MAPT Antibody Abstract)
Background Tau promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization. In Alzheimer disease, the neuronal cytoskeleton in the brain is progressively disrupted and replaced by tangles of paired helical filaments (PHF) and straight filaments, mainly composed of hyperphosphorylated forms of TAU.Synonyms: MAPTL, MTBT1, Microtubule-associated protein tau, Neurofibrillary tangle protein, PHF-tau, Paired helical filament-tau
Gene ID 4137
NCBI Accession NP_001116538
UniProt P10636
Research Area Cytoskeleton
Pathways MAPK Signaling, Microtubule Dynamics, M Phase, Regulation of Cell Size

Application Details

Product Details anti-MAPT Antibody Target Details MAPT Handling Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-MAPT Antibody Target Details MAPT Application Details Images back to top
Buffer PBS (without Mg2+, Ca2+), pH 7.4, 150 mM sodium chloride, 0.02 % sodium azide, 50 % glycerol
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage -20 °C
Storage Comment Store (in aliquots) at -20 °C.

Images

Product Details anti-MAPT Antibody Target Details MAPT Application Details Handling back to top
Supplier Images
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Microtubule-Associated Protein tau (MAPT) (Ser404) antibody (ABIN615572) Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Microtubule-Associated Protein tau (MAPT) (Ser404) antibody (ABIN615572) Human Nerve: Formalin-Fixed, Paraffin-Embedded (FFPE)