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anti-Rat (Rattus) MAPT antibody for Immunoprecipitation

Recommended MAPT Antibody (supplied by: Log in to see )

Antigen
Microtubule-Associated Protein tau (MAPT) Antibodies
  • AI413597
  • AI426939
  • AI551861
  • AW045860
  • AW457082
  • CK1epsilon
  • CKIe
  • DDPAC
  • FTDP-17
  • KC1epsilon
  • MAPT
  • MAPTL
  • MSTD
  • Mtapt
  • MTBT1
  • MTBT2
  • PHF-tau
  • PPND
  • pTau
  • RNPTAU
  • tau
  • Tau
  • TAU
  • xtp
Epitope
AA 23-179
60
43
39
39
38
37
37
34
30
29
28
28
25
19
17
17
15
14
14
13
12
12
12
11
11
11
10
10
10
9
9
9
9
8
8
8
7
7
6
6
6
6
5
4
4
4
4
4
4
4
4
4
3
3
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Rat (Rattus)
1043
527
506
97
37
33
21
21
19
9
5
4
4
3
3
3
3
2
2
1
1
1
1
Host
Mouse
954
141
11
9
Clonality
Monoclonal
Conjugate
This MAPT antibody is un-conjugated
25
10
10
7
4
4
3
3
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
Application
BioImaging (BI), Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (IHC), Western Blotting (WB)
933
355
327
149
82
69
60
36
14
12
12
12
11
9
4
3
2
1
Supplier
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Catalog No. ABIN968103
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Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.00089556724 ABIN1742567 ICC IP IHC WB Mouse IgG2a AA 3-214 Log in to see 248E5 2
0.00089556724 ABIN258511 ICC IF IHC (p) IP IHC WB Rabbit IgG AA 700-730 Log in to see E178
0.00089556724 ABIN1742569 ICC IP IHC WB Rabbit AA 3-214 Log in to see Polyclonal 2
0.00089556724 ABIN2705280 IP WB Rabbit C-Term, pSer713 Log in to see Polyclonal
0.00089556724 ABIN2705278 IC IF IP WB Rabbit C-Term Log in to see Polyclonal
0.00089556724 ABIN1742568 ICC IP IHC WB Rabbit AA 3-214 Log in to see Polyclonal 2
0.00089556724 ABIN307092 IP IHC WB Mouse IgG1 pan Log in to see TAU-5 3
0.00089556724 ABIN2506386 IP IHC WB Mouse IgG1 Log in to see TAU-93
0.00089556724 ABIN1690348 IP Magnetic Particles Mouse IgG1 Log in to see TAU-93
0.00089556724 ABIN1690695 IP Sepharose Mouse IgG1 Log in to see TAU-93

Top referenced anti-MAPT antibody for Immunoprecipitation

Similar anti-MAPT Antibodies

Application / Reactivity Rat (Rattus)
BioImaging (BI) 1 Antibodies
Dot Blot (DB) 2 Antibodies
ELISA 130 Antibodies
Enzyme Immunoassay (EIA) 1 Antibodies
Immunochromatography (IC) 2 Antibodies
Immunocytochemistry (ICC) 55 Antibodies
Immunofluorescence (IF) 99 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 11 Antibodies
Immunohistochemistry (IHC) 126 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 1 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 27 Antibodies
Immunoprecipitation (IP) 11 Antibodies
Western Blotting (WB) 440 Antibodies

General

Antigen Microtubule-Associated Protein tau (MAPT) Antibodies
Epitope AA 23-179
(60), (43), (39), (39), (38), (37), (37), (34), (30), (29), (28), (28), (25), (19), (17), (17), (15), (14), (14), (13), (12), (12), (12), (11), (11), (11), (10), (10), (10), (9), (9), (9), (9), (8), (8), (8), (7), (7), (6), (6), (6), (6), (5), (4), (4), (4), (4), (4), (4), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Rat (Rattus)
(1043), (527), (506), (97), (37), (33), (21), (21), (19), (9), (5), (4), (4), (3), (3), (3), (3), (2), (2), (1), (1), (1), (1)
Host Mouse
(954), (141), (11), (9)
Clonality (Clone)
Monoclonal   ( )
Conjugate This MAPT antibody is un-conjugated
(25), (10), (10), (7), (4), (4), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application BioImaging (BI), Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (IHC), Western Blotting (WB)
(933), (355), (327), (149), (82), (69), (60), (36), (14), (12), (12), (12), (11), (9), (4), (3), (2), (1)
Pubmed 5 references available
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Product Details anti-MAPT Antibody

Target Details MAPT Application Details Handling References for anti-MAPT Antibody (ABIN968103) Images
Cross-Reactivity Rat (Rattus)
Characteristics 1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
Purification The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
Immunogen Human Tau Recombinant Protein
Clone 15-Tau
Isotype IgG2b, kappa

Target Details MAPT

Product Details anti-MAPT Antibody Application Details Handling References for anti-MAPT Antibody (ABIN968103) Images back to top
Antigen
Alternative Name Tau (MAPT Antibody Abstract)
Background In addition to tubulin, microtubules have other components named Microtubule-associated proteins (MAPs), which include the high molecular MAPs (200-400 kDa) and the Tau proteins (55-70 kDa). These proteins co-purify with the microtubules during repeated cycles of microtubule assembly and disassembly. Both MAPs and Tau proteins extend from the side of the microtubules. They form cross-bridges in neurons and bind tubulin by their C-terminal region. The heterogeneity in the molecular weight of Tau proteins is due to post-translational modifications and different numbers of tandem repeats in their C-terminal domain. Tau isoforms are selectively expressed in unique subsets of neurons and regulated during development. The highly phosphorylated Tau proteins have also been detected in the neurofibrillary tangles of Alzheimer's patients. This antibody is routinely tested by western blot analysis.
Molecular Weight 50-68 kDa
Research Area Neurology, Cytoskeleton, Alzheimer's Disease
Pathways MAPK Signaling, Microtubule Dynamics

Application Details

Product Details anti-MAPT Antibody Target Details MAPT Handling References for anti-MAPT Antibody (ABIN968103) Images back to top
Comment

Related Products: ABIN968545, ABIN967389

Restrictions For Research Use only

Handling

Product Details anti-MAPT Antibody Target Details MAPT Application Details References for anti-MAPT Antibody (ABIN968103) Images back to top
Format Liquid
Concentration 250 μg/mL
Buffer Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store undiluted at -20°C.

References for anti-MAPT Antibody (ABIN968103)

Product Details anti-MAPT Antibody Target Details MAPT Application Details Handling Images back to top
Product cited in:

Takeda, Hatai, Hamazaki, Nishitoh, Saitoh, Ichijo: "Apoptosis signal-regulating kinase 1 (ASK1) induces neuronal differentiation and survival of PC12 cells." in: The Journal of biological chemistry, Vol. 275, Issue 13, pp. 9805-13, 2000

Wilson, Binder: "Free fatty acids stimulate the polymerization of tau and amyloid beta peptides. In vitro evidence for a common effector of pathogenesis in Alzheimer's disease." in: The American journal of pathology, Vol. 150, Issue 6, pp. 2181-95, 1997

Alonso, Grundke-Iqbal, Iqbal: "Alzheimer's disease hyperphosphorylated tau sequesters normal tau into tangles of filaments and disassembles microtubules." in: Nature medicine, Vol. 2, Issue 7, pp. 783-7, 1996

Kanai, Hirokawa: "Sorting mechanisms of tau and MAP2 in neurons: suppressed axonal transit of MAP2 and locally regulated microtubule binding." in: Neuron, Vol. 14, Issue 2, pp. 421-32, 1995

Goedert, Spillantini, Potier, Ulrich, Crowther: "Cloning and sequencing of the cDNA encoding an isoform of microtubule-associated protein tau containing four tandem repeats: differential expression of tau protein mRNAs in human brain." in: The EMBO journal, Vol. 8, Issue 2, pp. 393-9, 1989

Images

Product Details anti-MAPT Antibody Target Details MAPT Application Details Handling References for anti-MAPT Antibody (ABIN968103) back to top
Supplier Images
Western Blotting (WB) image for anti-MAPT antibody (Microtubule-Associated Protein tau) (AA 23-179) (ABIN968103) Western blot analysis of Tau on a rat cerebrum lysate. Lane 1: 1:1000, lane 2: 1:2000...
 image for anti-MAPT antibody (Microtubule-Associated Protein tau) (AA 23-179) (ABIN968103) Immunoflourescence staining of rat neurons.
 image for anti-MAPT antibody (Microtubule-Associated Protein tau) (AA 23-179) (ABIN968103) anti-Microtubule-Associated Protein tau (MAPT) (AA 23-179) antibody (Image 3)
Immunofluorescence (IF) image for anti-MAPT antibody (Microtubule-Associated Protein tau) (AA 23-179) (ABIN968103) anti-Microtubule-Associated Protein tau (MAPT) (AA 23-179) antibody (Image 4)
Western Blotting (WB) image for anti-MAPT antibody (Microtubule-Associated Protein tau) (AA 23-179) (ABIN968103) anti-Microtubule-Associated Protein tau (MAPT) (AA 23-179) antibody (Image 5)