You are viewing an incomplete version of our website. Please click to reload the website as full version.

anti-Human MCL-1 antibody for Immunofluorescence (Paraffin-embedded Sections)

Recommended MCL-1 Antibody (supplied by: Log in to see )

Antigen
Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1) Antibodies
  • AW556805
  • bcl2-L-3
  • BCL2L3
  • EAT
  • mcl-1
  • Mcl-1
  • MCL1-ES
  • mcl1/EAT
  • MCL1L
  • MCL1S
  • TM
Epitope
AA 210-248
32
23
22
15
15
13
13
12
11
10
9
5
3
3
3
3
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
290
101
67
9
8
5
4
3
2
2
1
1
Host
Rabbit
204
76
18
2
Clonality
Polyclonal
Conjugate
This MCL-1 antibody is un-conjugated
11
9
9
6
6
5
3
2
2
2
2
2
2
2
2
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
244
118
102
57
55
31
26
21
21
8
7
6
1
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Get this product for free

It's quick and easy to submit your validation proposal. I want to validate this product

Learn more

Available images

Catalog No. ABIN675369
$ 269.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0008812695 ABIN743738 IF (p) IHC (p) WB Rabbit IgG pSer159, pThr163 Log in to see Polyclonal
0.0008812695 ABIN905887 IF (p) Alexa Fluor 350 Rabbit IgG AA 210-248 Log in to see Polyclonal
0.0008812695 ABIN905886 IF (p) Alexa Fluor 555 Rabbit IgG AA 210-248 Log in to see Polyclonal
0.0008812695 ABIN905888 IF (p) Alexa Fluor 488 Rabbit IgG AA 210-248 Log in to see Polyclonal
0.0008812695 ABIN905885 IF (p) Alexa Fluor 647 Rabbit IgG AA 210-248 Log in to see Polyclonal
0.0008812695 ABIN675372 IF (p) Cy3 Rabbit IgG AA 210-248 Log in to see Polyclonal
0.0008812695 ABIN675373 IF (p) Cy5 Rabbit IgG AA 210-248 Log in to see Polyclonal
0.0008812695 ABIN675375 IF (p) Cy7 Rabbit IgG AA 210-248 Log in to see Polyclonal
0.0008812695 ABIN675374 IF (p) Cy5.5 Rabbit IgG AA 210-248 Log in to see Polyclonal
0.0008812695 ABIN675376 IF (p) FITC Rabbit IgG AA 210-248 Log in to see Polyclonal
0.0008812695 ABIN2804055 IF (p) Alexa Fluor 594 Rabbit IgG AA 140-190, pSer159, pThr163 Log in to see Polyclonal
0.0008812695 ABIN2804054 IF (p) Alexa Fluor 594 Rabbit IgG AA 210-248 Log in to see Polyclonal
0.0008812695 ABIN877540 IF (p) Alexa Fluor 647 Rabbit IgG pSer159, pThr163 Log in to see Polyclonal
0.0008812695 ABIN877538 IF (p) Alexa Fluor 488 Rabbit IgG pSer159, pThr163 Log in to see Polyclonal
0.0008812695 ABIN877536 IF (p) Alexa Fluor 555 Rabbit IgG pSer159, pThr163 Log in to see Polyclonal
0.0008812695 ABIN877537 IF (p) Alexa Fluor 350 Rabbit IgG pSer159, pThr163 Log in to see Polyclonal
0.0008812695 ABIN743745 IF (p) FITC Rabbit IgG pSer159, pThr163 Log in to see Polyclonal
0.0008812695 ABIN743741 IF (p) Cy3 Rabbit IgG pSer159, pThr163 Log in to see Polyclonal
0.0008812695 ABIN743742 IF (p) Cy5 Rabbit IgG pSer159, pThr163 Log in to see Polyclonal
0.0008812695 ABIN743743 IF (p) Cy5.5 Rabbit IgG pSer159, pThr163 Log in to see Polyclonal

Top referenced anti-MCL-1 antibody for Immunofluorescence (Paraffin-embedded Sections)

Similar anti-MCL-1 Antibodies

Application / Reactivity Rat (Rattus) Mouse (Murine)
ELISA 18 Antibodies 33 Antibodies
Enzyme Immunoassay (EIA) 1 Antibodies 2 Antibodies
Flow Cytometry (FACS) 2 Antibodies 7 Antibodies
Immunocytochemistry (ICC) 7 Antibodies 8 Antibodies
Immunofluorescence (IF) 5 Antibodies 9 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 22 Antibodies 22 Antibodies
Immunohistochemistry (IHC) 19 Antibodies 21 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 12 Antibodies 15 Antibodies
Immunoprecipitation (IP) 5 Antibodies
Western Blotting (WB) 45 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 1 Antibodies

General

Antigen Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1) Antibodies
Epitope AA 210-248
(32), (23), (22), (15), (15), (13), (13), (12), (11), (10), (9), (5), (3), (3), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(290), (101), (67), (9), (8), (5), (4), (3), (2), (2), (1), (1)
Host Rabbit
(204), (76), (18), (2)
Clonality
Polyclonal
Conjugate This MCL-1 antibody is un-conjugated
(11), (9), (9), (6), (6), (5), (3), (2), (2), (2), (2), (2), (2), (2), (2)
Application Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(244), (118), (102), (57), (55), (31), (26), (21), (21), (8), (7), (6), (1)
Pubmed 3 references available
Supplier Log in to see

Product Details anti-MCL-1 Antibody

Target Details MCL-1 Application Details Handling References for anti-MCL-1 Antibody (ABIN675369) Images
Purification Purified by Protein A.
Immunogen KLH conjugated synthetic peptide derived from human MCL1
Isotype IgG

Target Details MCL-1

Product Details anti-MCL-1 Antibody Application Details Handling References for anti-MCL-1 Antibody (ABIN675369) Images back to top
Antigen
Alternative Name Mcl1 (MCL1 Antibody Abstract)
Background

Involved in the regulation of apoptosis versus cell survival, and in the maintenance of viability but not of proliferation. Mediates its effects by interactions with a number of other regulators of apoptosis. Isoform 1 inhibits apoptosis. Isoform 2 promotes apoptosis.

Subcellular location: Helical


Synonyms: TM, EAT, MCL1L, MCL1S, Mcl-1, BCL2L3, MCL1-ES, bcl2-L-3, mcl1/EAT, Induced myeloid leukemia cell differentiation protein Mcl-1, Bcl-2-like protein 3, Bcl-2-related protein EAT/mcl1, MCL1
Gene ID 4170
UniProt Q07820
Research Area Cancer, Apoptosis/Necrosis
Pathways MAPK Signaling

Application Details

Product Details anti-MCL-1 Antibody Target Details MCL-1 Handling References for anti-MCL-1 Antibody (ABIN675369) Images back to top
Application Notes WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
Restrictions For Research Use only

Handling

Product Details anti-MCL-1 Antibody Target Details MCL-1 Application Details References for anti-MCL-1 Antibody (ABIN675369) Images back to top
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 100 μg/mL BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C
Expiry Date 12 months

References for anti-MCL-1 Antibody (ABIN675369)

Product Details anti-MCL-1 Antibody Target Details MCL-1 Application Details Handling Images back to top
Product cited in:

Chen, Xie, Zhao, Wang, Bai, Yin, Jiang, Xie, Jia, Huang et al.: "Ampelopsin induces apoptosis by regulating multiple c?Myc/S?phase kinase?associated protein 2/F?box and WD repeat?containing protein 7/histone deacetylase 2 pathways in human lung adenocarcinoma ..." in: Molecular medicine reports, Vol. 11, Issue 1, pp. 105-12, 2014

Zhang, Liu, Xia, Zhang, Zhang, Zhao, Chao, Jiang, Jiang: "Epithelial-mesenchymal transition is necessary for acquired resistance to cisplatin and increases the metastatic potential of nasopharyngeal carcinoma cells." in: International journal of molecular medicine, Vol. 33, Issue 1, pp. 151-9, 2013

Chen, Bai, Zhong, Xie, Long, Yang, Wu, Jia, Wang: "Wogonin has multiple anti-cancer effects by regulating c-Myc/SKP2/Fbw7? and HDAC1/HDAC2 pathways and inducing apoptosis in human lung adenocarcinoma cell line A549." in: PLoS ONE, Vol. 8, Issue 11, pp. e79201, 2013

Images

Product Details anti-MCL-1 Antibody Target Details MCL-1 Application Details Handling References for anti-MCL-1 Antibody (ABIN675369) back to top
Supplier Images
Western Blotting (WB) image for anti-MCL-1 antibody (Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1) (AA 210-248) (ABIN675369) Mouse spleen lysates probed with Rabbit Anti-MCL1 Polyclonal Antibody, Unconjugated ...