anti-Human MCL-1 antibody for Immunofluorescence (Paraffin-embedded Sections)

Recommended MCL-1 Antibody (supplied by: Log in to see )

Antigen
Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1) Antibodies
  • AW556805
  • Mcl-1
  • BCL2L3
  • EAT
  • MCL1-ES
  • MCL1L
  • MCL1S
  • TM
  • bcl2-L-3
  • mcl1/EAT
  • mcl-1
  • myeloid cell leukemia sequence 1
  • myeloid cell leukemia sequence 1 (BCL2-related)
  • Mcl1
  • MCL1
Epitope
AA 210-248
31
22
19
17
15
14
14
13
11
9
7
5
4
3
3
3
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
330
126
82
13
13
10
8
3
3
3
2
1
1
1
Host
Rabbit
219
97
22
2
Clonality
Polyclonal
Conjugate
This MCL-1 antibody is un-conjugated
12
10
10
6
5
5
3
3
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
281
141
117
91
80
45
31
29
25
25
6
5
5
1
Options
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Catalog No. ABIN675369
$ 307.45
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN743738 IF (p) IHC (p) WB Rabbit IgG pSer159, pThr163 Log in to see Polyclonal
1 ABIN2804054 IF (p) Alexa Fluor 594 Rabbit IgG AA 210-248 Log in to see Polyclonal
1 ABIN743741 IF (p) Cy3 Rabbit IgG pSer159, pThr163 Log in to see Polyclonal
1 ABIN743743 IF (p) Cy5.5 Rabbit IgG pSer159, pThr163 Log in to see Polyclonal
1 ABIN743742 IF (p) Cy5 Rabbit IgG pSer159, pThr163 Log in to see Polyclonal
1 ABIN743745 IF (p) FITC Rabbit IgG pSer159, pThr163 Log in to see Polyclonal
1 ABIN743744 IF (p) Cy7 Rabbit IgG pSer159, pThr163 Log in to see Polyclonal
1 ABIN675372 IF (p) Cy3 Rabbit IgG AA 210-248 Log in to see Polyclonal
1 ABIN675375 IF (p) Cy7 Rabbit IgG AA 210-248 Log in to see Polyclonal
1 ABIN675376 IF (p) FITC Rabbit IgG AA 210-248 Log in to see Polyclonal
1 ABIN675373 IF (p) Cy5 Rabbit IgG AA 210-248 Log in to see Polyclonal
1 ABIN675374 IF (p) Cy5.5 Rabbit IgG AA 210-248 Log in to see Polyclonal
1 ABIN877537 IF (p) Alexa Fluor 350 Rabbit IgG pSer159, pThr163 Log in to see Polyclonal
1 ABIN877538 IF (p) Alexa Fluor 488 Rabbit IgG pSer159, pThr163 Log in to see Polyclonal
1 ABIN877540 IF (p) Alexa Fluor 647 Rabbit IgG pSer159, pThr163 Log in to see Polyclonal
1 ABIN877536 IF (p) Alexa Fluor 555 Rabbit IgG pSer159, pThr163 Log in to see Polyclonal
1 ABIN905885 IF (p) Alexa Fluor 647 Rabbit IgG AA 210-248 Log in to see Polyclonal
1 ABIN905886 IF (p) Alexa Fluor 555 Rabbit IgG AA 210-248 Log in to see Polyclonal
1 ABIN905887 IF (p) Alexa Fluor 350 Rabbit IgG AA 210-248 Log in to see Polyclonal
1 ABIN905888 IF (p) Alexa Fluor 488 Rabbit IgG AA 210-248 Log in to see Polyclonal

General

Antigen Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1) Antibodies
Epitope AA 210-248
(31), (22), (19), (17), (15), (14), (14), (13), (11), (9), (7), (5), (4), (3), (3), (3), (3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(330), (126), (82), (13), (13), (10), (8), (3), (3), (3), (2), (1), (1), (1)
Host Rabbit
(219), (97), (22), (2)
Clonality
Polyclonal
Conjugate This MCL-1 antibody is un-conjugated
(12), (10), (10), (6), (5), (5), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(281), (141), (117), (91), (80), (45), (31), (29), (25), (25), (6), (5), (5), (1)
Pubmed 4 references available
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Product Details anti-MCL-1 Antibody

Target Details MCL-1 Application Details Handling ProductDetails: References for anti-MCL-1 antibody (ABIN675369) Images
Purification Purified by Protein A.
Immunogen KLH conjugated synthetic peptide derived from human MCL1
Isotype IgG

Target Details MCL-1

Product Details anti-MCL-1 Antibody Application Details Handling ProductDetails: References for anti-MCL-1 antibody (ABIN675369) Images back to top
Antigen
Alternative Name Mcl1 (MCL1 Antibody Abstract)
Background

Involved in the regulation of apoptosis versus cell survival, and in the maintenance of viability but not of proliferation. Mediates its effects by interactions with a number of other regulators of apoptosis. Isoform 1 inhibits apoptosis. Isoform 2 promotes apoptosis.

Subcellular location: Helical

Synonyms: TM, EAT, MCL1L, MCL1S, Mcl-1, BCL2L3, MCL1-ES, bcl2-L-3, mcl1/EAT, Induced myeloid leukemia cell differentiation protein Mcl-1, Bcl-2-like protein 3, Bcl-2-related protein EAT/mcl1, MCL1

Gene ID 4170
UniProt Q07820
Research Area Cancer, Apoptosis/Necrosis
Pathways MAPK Signaling

Application Details

Product Details anti-MCL-1 Antibody Target Details MCL-1 Handling ProductDetails: References for anti-MCL-1 antibody (ABIN675369) Images back to top
Application Notes WB 1:100-1000
IHC-P 1:100-500
IF(IHC-P) 1:50-200
Restrictions For Research Use only

Handling

Product Details anti-MCL-1 Antibody Target Details MCL-1 Application Details ProductDetails: References for anti-MCL-1 antibody (ABIN675369) Images back to top
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C
Expiry Date 12 months

ProductDetails: References for anti-MCL-1 antibody (ABIN675369)

Product Details anti-MCL-1 Antibody Target Details MCL-1 Application Details Handling Images back to top
Product cited in:

Wang, Zhang, Wang, Wang, Wang, Wu, Wu, Zhang, Zhang: "A small hairpin RNA targeting myeloid cell leukemia-1 enhances apoptosis in host macrophages infected with Mycobacterium tuberculosis." in: Journal of microbiology (Seoul, Korea), Vol. 54, Issue 4, pp. 330-7, 2016

Chen, Xie, Zhao, Wang, Bai, Yin, Jiang, Xie, Jia, Huang et al.: "Ampelopsin induces apoptosis by regulating multiple c?Myc/S?phase kinase?associated protein 2/F?box and WD repeat?containing protein 7/histone deacetylase 2 pathways in human lung adenocarcinoma ..." in: Molecular medicine reports, Vol. 11, Issue 1, pp. 105-12, 2014 Method employed by authors: Western Blotting (WB) (Sample species: Human).

Zhang, Liu, Xia, Zhang, Zhang, Zhao, Chao, Jiang, Jiang: "Epithelial-mesenchymal transition is necessary for acquired resistance to cisplatin and increases the metastatic potential of nasopharyngeal carcinoma cells." in: International journal of molecular medicine, Vol. 33, Issue 1, pp. 151-9, 2013

Chen, Bai, Zhong, Xie, Long, Yang, Wu, Jia, Wang: "Wogonin has multiple anti-cancer effects by regulating c-Myc/SKP2/Fbw7? and HDAC1/HDAC2 pathways and inducing apoptosis in human lung adenocarcinoma cell line A549." in: PLoS ONE, Vol. 8, Issue 11, pp. e79201, 2013

Images

Product Details anti-MCL-1 Antibody Target Details MCL-1 Application Details Handling ProductDetails: References for anti-MCL-1 antibody (ABIN675369) back to top
Supplier Images
Western Blotting (WB) image for anti-Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1) (AA 210-248) antibody (ABIN675369) Mouse spleen lysates probed with Rabbit Anti-MCL1 Polyclonal Antibody, Unconjugated ...