You are viewing an incomplete version of our website. Please click to reload the website as full version.

anti-Rat (Rattus) MCL-1 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended MCL-1 Antibody (supplied by: Log in to see )

Antigen
Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1) Antibodies
  • AW556805
  • bcl2-L-3
  • BCL2L3
  • EAT
  • mcl-1
  • Mcl-1
  • MCL1-ES
  • mcl1/EAT
  • MCL1L
  • MCL1S
  • TM
Epitope
C-Term
31
23
22
15
15
13
13
13
11
10
9
5
3
3
3
3
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
290
101
67
9
8
5
4
3
2
2
1
1
Host
Rabbit
204
76
18
2
Clonality
Polyclonal
Conjugate
This MCL-1 antibody is un-conjugated
11
9
9
6
6
5
3
2
2
2
2
2
2
2
2
Application
Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
244
118
102
57
54
31
26
22
21
8
7
6
1
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Get this product for free

It's quick and easy to submit your validation proposal. I want to validate this product

Learn more

Available images

Catalog No. ABIN303283
$ 500.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.00089715846 ABIN675369 IF (p) IHC (p) WB Rabbit IgG AA 210-248 Log in to see Polyclonal 3
0.00089715846 ABIN265513 IHC (p) WB Rabbit Log in to see Polyclonal
0.00089715846 ABIN126984 IHC (p) IP WB Rabbit Log in to see Polyclonal
0.00089715846 ABIN3043876 IHC (p) WB Rabbit IgG AA 1-350 Log in to see Polyclonal
0.00089715846 ABIN743738 IF (p) IHC (p) WB Rabbit IgG pSer159, pThr163 Log in to see Polyclonal
0.00089715846 ABIN1736826 ICC IHC (p) WB Rabbit IgG C-Term Log in to see Polyclonal
0.00089715846 ABIN675371 IHC (p) WB Biotin Rabbit IgG AA 210-248 Log in to see Polyclonal
0.00089715846 ABIN675378 IHC (p) WB HRP Rabbit IgG AA 210-248 Log in to see Polyclonal
0.00089715846 ABIN743747 IHC (p) WB HRP Rabbit IgG pSer159, pThr163 Log in to see Polyclonal
0.00089715846 ABIN743740 IHC (p) WB Biotin Rabbit IgG pSer159, pThr163 Log in to see Polyclonal
0.00089715846 ABIN3031298 IHC (p) WB Rabbit IgG AA 1-350 Log in to see Polyclonal

Top referenced anti-MCL-1 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Similar anti-MCL-1 Antibodies

Application / Reactivity Rat (Rattus) Mouse (Murine)
ELISA 18 Antibodies 33 Antibodies
Enzyme Immunoassay (EIA) 1 Antibodies 2 Antibodies
Flow Cytometry (FACS) 2 Antibodies 7 Antibodies
Immunocytochemistry (ICC) 7 Antibodies 8 Antibodies
Immunofluorescence (IF) 5 Antibodies 9 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 22 Antibodies 22 Antibodies
Immunohistochemistry (IHC) 19 Antibodies 21 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 12 Antibodies 15 Antibodies
Immunoprecipitation (IP) 5 Antibodies
Western Blotting (WB) 45 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 1 Antibodies

General

Antigen Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1) Antibodies
Epitope C-Term
(31), (23), (22), (15), (15), (13), (13), (13), (11), (10), (9), (5), (3), (3), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(290), (101), (67), (9), (8), (5), (4), (3), (2), (2), (1), (1)
Host Rabbit
(204), (76), (18), (2)
Clonality
Polyclonal
Conjugate This MCL-1 antibody is un-conjugated
(11), (9), (9), (6), (6), (5), (3), (2), (2), (2), (2), (2), (2), (2), (2)
Application Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(244), (118), (102), (57), (54), (31), (26), (22), (21), (8), (7), (6), (1)
Pubmed 1 reference available
Supplier Log in to see

Product Details anti-MCL-1 Antibody

Target Details MCL-1 Application Details Handling References for anti-MCL-1 Antibody (ABIN303283) Images
Specificity This antibody recognises Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1
Purification Ion Exchange chromatography.
Immunogen Synthetic peptide corresponding to 16 amino acids near the carboxy-terminus of human Mcl-1.

Target Details MCL-1

Product Details anti-MCL-1 Antibody Application Details Handling References for anti-MCL-1 Antibody (ABIN303283) Images back to top
Antigen
Alternative Name MCL1 (MCL1 Antibody Abstract)
Background Myeloid cell leukimia-1 (Mcl-1) is a member of the Bcl-2 family of proteins that can act to promote cell survival. While the mechanism by which Mcl-1 inhibits apoptosis is not known, it is thought that it may heterodimerize and neutralize pro-apoptotic members of the Bcl-2 family such as Bim or Bak. Mcl-1 was originally identified in differentiating myeloid cells, but has since been shown to be expressed in multiple cell types. Mcl-1 is essential for embryogenesis (5) and for the development and maintenance of B and T lymphocytes in animals. Mcl-1 exists as at least two distinct isoforms designated Mcl-1L and Mcl-1S. In marked contrast to the larger isoform of Mcl-1, overexpression of Mcl-1S promotes cell death.Synonyms: BCL2L3, Bcl-2-like protein 3, Bcl-2-related protein, EAT, Induced myeloid leukemia cell differentiation protein Mcl-1, mcl1/EAT, r004
Gene ID 4170
NCBI Accession NP_001184249
UniProt Q07820
Research Area Cancer, Apoptosis/Necrosis
Pathways MAPK Signaling

Application Details

Product Details anti-MCL-1 Antibody Target Details MCL-1 Handling References for anti-MCL-1 Antibody (ABIN303283) Images back to top
Application Notes Immunohistochemistry on Paraffin Sections (2.5 μg/mL). Immunocytochemistry. Western Blot (1-2 μg/mL).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-MCL-1 Antibody Target Details MCL-1 Application Details References for anti-MCL-1 Antibody (ABIN303283) Images back to top
Concentration 1.0 mg/mL
Buffer Phosphate Buffered Saline PBS containing 0.02 % Sodium Azide as preservative.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer. Dilute only prior to immediate use.

References for anti-MCL-1 Antibody (ABIN303283)

Product Details anti-MCL-1 Antibody Target Details MCL-1 Application Details Handling Images back to top
Background publications

Kozopas, Yang, Buchan, Zhou, Craig: "MCL1, a gene expressed in programmed myeloid cell differentiation, has sequence similarity to BCL2." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 90, Issue 8, pp. 3516-20, 1993

Images

Product Details anti-MCL-1 Antibody Target Details MCL-1 Application Details Handling References for anti-MCL-1 Antibody (ABIN303283) back to top
Supplier Images
 image for anti-MCL-1 antibody (Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1) (C-Term) (ABIN303283) anti-Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1) (C-Term) antibody