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Browse our anti-MKNK1 (MKNK1) Antibodies

Full name:
anti-MAP Kinase Interacting serine/threonine Kinase 1 Antibodies (MKNK1)
On www.antibodies-online.com are 135 MAP Kinase Interacting serine/threonine Kinase 1 (MKNK1) Antibodies from 15 different suppliers available. Additionally we are shipping MKNK1 Proteins (9) and MKNK1 Kits (6) and many more products for this protein. A total of 162 MKNK1 products are currently listed.
Synonyms:
2410048M24Rik, Erk-1, Erk1, Ert2, Esrk1, MAPK1, MKNK1, Mnk1, Mtap2k, p44, p44erk1, p44mapk, Prkm3, zgc:171912
list all antibodies Gene Name GeneID UniProt
MKNK1 8569 Q9BUB5
MKNK1 17346 O08605
MKNK1 500526 Q4G050

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Most Popular Reactivities for anti-MKNK1 (MKNK1) Antibodies

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anti-Human MKNK1 Antibodies:

anti-Mouse (Murine) MKNK1 Antibodies:

anti-Rat (Rattus) MKNK1 Antibodies:

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Top referenced anti-MKNK1 Antibodies

  1. Human Polyclonal MKNK1 Primary Antibody for EIA, WB - ABIN359308 : Orton, Ling, Waskiewicz, Cooper, Merrick, Korneeva, Rhoads, Sonenberg, Traugh: Phosphorylation of Mnk1 by caspase-activated Pak2/gamma-PAK inhibits phosphorylation and interaction of eIF4G with Mnk. in The Journal of biological chemistry 2004 (PubMed)

More Antibodies against MKNK1 Interaction Partners

Human MAP Kinase Interacting serine/threonine Kinase 1 (MKNK1) interaction partners

  1. Data suggest MNK1/MNK2 (show MKNK2 Antibodies) stimulate mRNA translation but only of mRNA containing both 5-prime-terminal cap and hairpin duplex; this stimulation involves up-regulation of phosphorylation/mRNA un-winding activity of eIF4E (show EIF4E Antibodies) (via decreased binding to eIF4G (show EIF4G1 Antibodies)).

  2. Simultaneous targeting of androgen receptor (show AR Antibodies) and MNK1 by novel retinamides inhibits growth of human prostate cancer cell lines.

  3. MNK1 and MNK2 (show MKNK2 Antibodies) inhibition ablates eIF4E1 (show EIF4E Antibodies) phosphorylation and concurrently enhances eIF4E3 (show EIF4E3 Antibodies) expression in diffuse large B-cell lymphoma.

  4. Data show that interferon-gamma (show IFNG Antibodies) regulated the metabolism and mRNA translation of macrophages by targeting the kinases mTORC1 and MNK1/2, both of which converge on the selective regulator of translation initiation eukaryotic initiation factor-4E (eIF4E (show EIF4E Antibodies)).

  5. Data suggest that a combined pharmacologic inhibition of mTORC1 and Mnk1/2 kinases offers a therapeutic opportunity in blast crisis-chronic myeloid leukemia (BC-CML).

  6. Authors show that MNK (show ATP7A Antibodies) regulates SRPK (show SRPK1 Antibodies) via mTOR (show FRAP1 Antibodies) and AKT (show AKT1 Antibodies).

  7. ERK1/2 (show MAPK1/3 Antibodies) signal induced MNK (show ATP7A Antibodies) catalytic activity enabled enterovirus type 1 internal ribosomal entry site-mediated translation/host cell cytotoxicity through negative regulation of the Ser (show SIGLEC1 Antibodies)/Arg (SR)-rich protein kinase (show CDK7 Antibodies) (SRPK (show SRPK1 Antibodies)).

  8. These data indicate multiple myeloma cells exploit the MNK (show ATP7A Antibodies)/eIF-4E (show EIF4E Antibodies) pathway for selective mRNA translation without enhancing global translation and risking ER stress.

  9. High expression of p-Mnk1 and p-eIF4E (show EIF4E Antibodies) might be novel valuable biomarkers to predict poor prognosis of nasopharyngeal carcinoma.

  10. rapalog-activated MNK1 signaling promotes glioma growth through regulation of 4EBP1 (show EIF4EBP1 Antibodies); there is a molecular cross-talk between the mTORC1 and MNK1 pathways

Mouse (Murine) MAP Kinase Interacting serine/threonine Kinase 1 (MKNK1) interaction partners

  1. ERK (show EPHB2 Antibodies) contributes to the morphine-induced hyperalgesia by regulating the activation of c-JUN (show JUN Antibodies)

  2. Consistent with the essential role of ERK1/2 (show MAPK1/3 Antibodies) during macrophage differentiation and defects of macrophagic differentiation in native ERK1 (show MAPK3 Antibodies)(-/-) progenitors, ERK (show EPHB2 Antibodies) signaling is strongly activated in Eger/Fms (show CSF1R Antibodies) cells upon M-CSF (show CSF1R Antibodies)-induced macrophage differentiation.

  3. CXCR4 (show CXCR4 Antibodies) inhibitor attenuates allergen-induced lung inflammation by down-regulating MMP-9 (show MMP9 Antibodies) and ERK1/2 (show MAPK1/3 Antibodies) expression.

  4. Myocardial FasL (show FASL Antibodies) expression in mice activates differential robust fibrotic, apoptotic and inflammatory responses via ERK1/2 (show MAPK1/3 Antibodies) in cardiomyocytes and cardiac fibroblasts inducing dilated cardiomyopathy/heart failure.

  5. Cx43 (show GJA1 Antibodies) regulates FGF10 (show FGF10 Antibodies)-induced ERK1/2 (show MAPK1/3 Antibodies) phosphorylation in salivary epithelium.

  6. ERK1/2 (show MAPK1/3 Antibodies) plays an important role in TGF-beta1 (show TGFB1 Antibodies)-induced mTOR (show FRAP1 Antibodies) activation and translational regulation of Nox4 (show NOX4 Antibodies) protein.

  7. T1R1 (show TAS1R1 Antibodies)/T1R3 (show TAS1R3 Antibodies) have roles in regulating ERK1/2 (show MAPK1/3 Antibodies) and mTORC1 in MIN6 cells

  8. ERK (show EPHB2 Antibodies)/GSK3beta (show GSK3b Antibodies) signaling was involved in the apoptotic and G1 phase arrest effects of AT-I in melanoma cells.

  9. These results suggest that in addition to the Mos (show MOS Antibodies)-MEK1 (show MAP2K1 Antibodies)/2 pathway, the Mos (show MOS Antibodies)-mediated p38 (show CRK Antibodies) pathway may be implicated in metaphase-II arrest.

  10. The role of ERK1 (show MAPK3 Antibodies) and ERK2 (show MAPK1 Antibodies) in chondrocyte terminal differentiation, was investigated.

MKNK1 Antigen Profile

Antigen Summary

This gene encodes a Ser/Thr protein kinase that interacts with, and is activated by ERK1 and p38 mitogen-activated protein kinases, and thus may play a role in the response to environmental stress and cytokines. This kinase may also regulate transcription by phosphorylating eIF4E via interaction with the C-terminal region of eIF4G. Alternatively spliced transcript variants have been noted for this gene.

Alternative names and synonyms associated with MKNK1

  • MAP kinase interacting serine/threonine kinase 1 (MKNK1) antibody
  • MAP kinase interacting serine/threonine kinase 1 (mknk1) antibody
  • MAP kinase-interacting serine/threonine kinase 1 (Mknk1) antibody
  • mitogen activated protein kinase 3 (Mapk3) antibody
  • mitogen-activated protein kinase 3 (Mapk3) antibody
  • 2410048M24Rik antibody
  • Erk-1 antibody
  • Erk1 antibody
  • Ert2 antibody
  • Esrk1 antibody
  • MAPK1 antibody
  • MKNK1 antibody
  • Mnk1 antibody
  • Mtap2k antibody
  • p44 antibody
  • p44erk1 antibody
  • p44mapk antibody
  • Prkm3 antibody
  • zgc:171912 antibody

Protein level used designations for MKNK1

MAP kinase interacting serine/threonine kinase 1 , MAP kinase-interacting serine/threonine-protein kinase 1 , MAP kinase signal-integrating kinase 1 , MAPK signal-integrating kinase 1 , mnk1 , MAP kinase 1 , MAP kinase 3 , MAP kinase isoform p44 , MAPK 1 , MAPK 3 , extracellular signal-regulated kinase 1 , insulin-stimulated MAP2 kinase , microtubule-associated protein 2 kinase , mitogen-activated 3 , mitogen-activated protein kinase 1 , mitogen-activated protein kinase 3 , p44 MAP kinase , pp42/MAP kinase

GENE ID SPECIES
469189 Pan troglodytes
555974 Danio rerio
771961 Gallus gallus
8569 Homo sapiens
525647 Bos taurus
17346 Mus musculus
500526 Rattus norvegicus
50689 Rattus norvegicus
26417 Mus musculus
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