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Browse our anti-MKNK1 (MKNK1) Antibodies

Full name:
anti-MAP Kinase Interacting serine/threonine Kinase 1 Antibodies (MKNK1)
On are 134 MAP Kinase Interacting serine/threonine Kinase 1 (MKNK1) Antibodies from 18 different suppliers available. Additionally we are shipping MKNK1 Proteins (10) and MKNK1 Kits (6) and many more products for this protein. A total of 163 MKNK1 products are currently listed.
2410048M24Rik, Erk-1, Erk1, Ert2, Esrk1, MAPK1, MKNK1, Mnk1, Mtap2k, p44, p44erk1, p44mapk, Prkm3, zgc:171912
list all antibodies Gene Name GeneID UniProt
MKNK1 8569 Q9BUB5
MKNK1 17346 O08605
MKNK1 500526 Q4G050

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anti-Human MKNK1 Antibodies:

anti-Mouse (Murine) MKNK1 Antibodies:

anti-Rat (Rattus) MKNK1 Antibodies:

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Top referenced anti-MKNK1 Antibodies

  1. Human Polyclonal MKNK1 Primary Antibody for EIA, WB - ABIN359308 : Orton, Ling, Waskiewicz, Cooper, Merrick, Korneeva, Rhoads, Sonenberg, Traugh: Phosphorylation of Mnk1 by caspase-activated Pak2/gamma-PAK inhibits phosphorylation and interaction of eIF4G with Mnk. in The Journal of biological chemistry 2004 (PubMed)

More Antibodies against MKNK1 Interaction Partners

Human MAP Kinase Interacting serine/threonine Kinase 1 (MKNK1) interaction partners

  1. data suggest a physiological role for MNK1a-Ser (show SIGLEC1 Antibodies)(353) phosphorylation in regulation of the MNK1a kinase, which correlates with increased eIF4E (show EIF4E Antibodies) phosphorylation in vitro and in vivo.

  2. Data suggest MNK1/MNK2 (show MKNK2 Antibodies) stimulate mRNA translation but only of mRNA containing both 5-prime-terminal cap and hairpin duplex; this stimulation involves up-regulation of phosphorylation/mRNA un-winding activity of eIF4E (show EIF4E Antibodies) (via decreased binding to eIF4G (show EIF4G1 Antibodies)).

  3. Simultaneous targeting of androgen receptor (show AR Antibodies) and MNK1 by novel retinamides inhibits growth of human prostate cancer cell lines.

  4. MNK1 and MNK2 (show MKNK2 Antibodies) inhibition ablates eIF4E1 (show EIF4E Antibodies) phosphorylation and concurrently enhances eIF4E3 (show EIF4E3 Antibodies) expression in diffuse large B-cell lymphoma.

  5. Data show that interferon-gamma (show IFNG Antibodies) regulated the metabolism and mRNA translation of macrophages by targeting the kinases mTORC1 and MNK1/2, both of which converge on the selective regulator of translation initiation eukaryotic initiation factor-4E (eIF4E (show EIF4E Antibodies)).

  6. Data suggest that a combined pharmacologic inhibition of mTORC1 and Mnk1/2 kinases offers a therapeutic opportunity in blast crisis-chronic myeloid leukemia (BC-CML).

  7. Authors show that MNK (show ATP7A Antibodies) regulates SRPK (show SRPK1 Antibodies) via mTOR (show FRAP1 Antibodies) and AKT (show AKT1 Antibodies).

  8. ERK1/2 (show MAPK1/3 Antibodies) signal induced MNK (show ATP7A Antibodies) catalytic activity enabled enterovirus type 1 internal ribosomal entry site-mediated translation/host cell cytotoxicity through negative regulation of the Ser (show SIGLEC1 Antibodies)/Arg (SR)-rich protein kinase (show CDK7 Antibodies) (SRPK (show SRPK1 Antibodies)).

  9. These data indicate multiple myeloma cells exploit the MNK (show ATP7A Antibodies)/eIF-4E (show EIF4E Antibodies) pathway for selective mRNA translation without enhancing global translation and risking ER stress.

  10. High expression of p-Mnk1 and p-eIF4E (show EIF4E Antibodies) might be novel valuable biomarkers to predict poor prognosis of nasopharyngeal carcinoma.

Mouse (Murine) MAP Kinase Interacting serine/threonine Kinase 1 (MKNK1) interaction partners

  1. We also demonstrated that ERK1 (show MAPK3 Antibodies) deletion potentiates DC vaccination and provides a survival advantage in high-grade gliomas.

  2. Low frequency pulsed electromagnetic field (PEMF) induced the activation of extracellular signal-regulated kinases ERK1/2 (show MAPK1/3 Antibodies), and the phosphorylation level of ERK1/2 (show MAPK1/3 Antibodies) increased after 15 min when exposed to PEMF.

  3. A- and B-Raf ablation in chondrocytes does not alter skeletal development, whereas ablation of C-Raf decreases hypertrophic chondrocyte apoptosis and impairs vascularization of the growth plate. However, ablation of C-Raf does not impair phosphate-induced ERK1/2 phosphorylation in vitro, but leads to rickets by decreasing VEGF protein stability.

  4. RKIP (show PEBP1 Antibodies) knockdown promotes ERK1 (show MAPK3 Antibodies) and PPAR gamma (show PPARG Antibodies) activation during adipogenesis.

  5. data suggest a physiological role for MNK1a-Ser (show SIGLEC1 Antibodies)(353) phosphorylation in regulation of the MNK1a kinase, which correlates with increased eIF4E (show EIF4E Antibodies) phosphorylation in vitro and in vivo.

  6. Results indicate that methanol extract of Thunbergia alata (MTA (show DNMT1 Antibodies)) selectively inhibits the excessive production of inflammatory mediators in macrophages by reducing phosphorylation of extracellular signalregulated kinase (ERK (show EPHB2 Antibodies)) and signal transducer and activator of transcription 3 (STAT3 (show STAT3 Antibodies)).

  7. Neuroprotective effects of oleoylethanolamide on cerebral ischemia may be attributed to its antiapoptotic property achieved, at least in part, through the PPARalpha (show PPARA Antibodies) signaling and inhibition of both TLR4 (show TLR4 Antibodies)/NF-kappaB (show NFKB1 Antibodies) and ERK1/2 (show MAPK1/3 Antibodies) signaling pathways.

  8. These results indicated that the activation of the ERK1/2 (show MAPK1/3 Antibodies) signal transduction pathway may have an important role in glucosestimulated insulin (show INS Antibodies) secretion in betaTC6 cells.

  9. PI3K, MAPK/ERK (show MAPK1 Antibodies) 1 (show MAPK3 Antibodies)/2, and p38 (show CRK Antibodies)-signaling proteins are not the main regulators of local production of erythropoietin (show EPO Antibodies) after 30% loss of circulating blood volume.

  10. Lipopolysaccharides significantly up-regulated RANKL (show TNFSF11 Antibodies) expression and activated the ERK1/2 (show MAPK1/3 Antibodies) pathway to induce IL-6 (show IL6 Antibodies) mRNA expression and protein synthesis in MLO-Y4 cells.

MKNK1 Antigen Profile

Antigen Summary

This gene encodes a Ser/Thr protein kinase that interacts with, and is activated by ERK1 and p38 mitogen-activated protein kinases, and thus may play a role in the response to environmental stress and cytokines. This kinase may also regulate transcription by phosphorylating eIF4E via interaction with the C-terminal region of eIF4G. Alternatively spliced transcript variants have been noted for this gene.

Alternative names and synonyms associated with MKNK1

  • MAP kinase interacting serine/threonine kinase 1 (MKNK1) antibody
  • MAP kinase interacting serine/threonine kinase 1 (mknk1) antibody
  • MAP kinase-interacting serine/threonine kinase 1 (Mknk1) antibody
  • mitogen activated protein kinase 3 (Mapk3) antibody
  • mitogen-activated protein kinase 3 (Mapk3) antibody
  • 2410048M24Rik antibody
  • Erk-1 antibody
  • Erk1 antibody
  • Ert2 antibody
  • Esrk1 antibody
  • MAPK1 antibody
  • MKNK1 antibody
  • Mnk1 antibody
  • Mtap2k antibody
  • p44 antibody
  • p44erk1 antibody
  • p44mapk antibody
  • Prkm3 antibody
  • zgc:171912 antibody

Protein level used designations for MKNK1

MAP kinase interacting serine/threonine kinase 1 , MAP kinase-interacting serine/threonine-protein kinase 1 , MAP kinase signal-integrating kinase 1 , MAPK signal-integrating kinase 1 , mnk1 , MAP kinase 1 , MAP kinase 3 , MAP kinase isoform p44 , MAPK 1 , MAPK 3 , extracellular signal-regulated kinase 1 , insulin-stimulated MAP2 kinase , microtubule-associated protein 2 kinase , mitogen-activated 3 , mitogen-activated protein kinase 1 , mitogen-activated protein kinase 3 , p44 MAP kinase , pp42/MAP kinase

469189 Pan troglodytes
555974 Danio rerio
771961 Gallus gallus
8569 Homo sapiens
525647 Bos taurus
17346 Mus musculus
500526 Rattus norvegicus
50689 Rattus norvegicus
26417 Mus musculus
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