Browse our anti-MKNK1 (MKNK1) Antibodies

Full name:
anti-MAP Kinase Interacting serine/threonine Kinase 1 Antibodies (MKNK1)
On www.antibodies-online.com are 135 MAP Kinase Interacting serine/threonine Kinase 1 (MKNK1) Antibodies from 18 different suppliers available. Additionally we are shipping MKNK1 Proteins (11) and MKNK1 Kits (6) and many more products for this protein. A total of 165 MKNK1 products are currently listed.
Synonyms:
2410048M24Rik, Erk-1, Erk1, Ert2, Esrk1, MAPK1, MKNK1, Mnk1, Mtap2k, p44, p44erk1, p44mapk, Prkm3, zgc:171912
list all antibodies Gene Name GeneID UniProt
MKNK1 8569 Q9BUB5
MKNK1 17346 O08605
MKNK1 500526 Q4G050

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anti-Human MKNK1 Antibodies:

anti-Mouse (Murine) MKNK1 Antibodies:

anti-Rat (Rattus) MKNK1 Antibodies:

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Top referenced anti-MKNK1 Antibodies

  1. Human Polyclonal MKNK1 Primary Antibody for EIA, WB - ABIN359308 : Orton, Ling, Waskiewicz, Cooper, Merrick, Korneeva, Rhoads, Sonenberg, Traugh: Phosphorylation of Mnk1 by caspase-activated Pak2/gamma-PAK inhibits phosphorylation and interaction of eIF4G with Mnk. in The Journal of biological chemistry 2004 (PubMed)

More Antibodies against MKNK1 Interaction Partners

Human MAP Kinase Interacting serine/threonine Kinase 1 (MKNK1) interaction partners

  1. MNK1 encodes a Ser/Thr protein kinase that interacts with extracellular signal-regulated kinase 1 (show MAPK3 Antibodies) and p38 mitogen-activated protein kinase (show MAPK14 Antibodies), a pathway that is involved in Blood Pressure regulation through norepinephrine and angiotensin II.

  2. Data show that galeterone (gal (show GAL Antibodies)) and VNPT55 inhibit migration and invasion of prostate cancer cells, possibly by down-regulating protein expression via antagonizing the Mnk1/2-eIF4E (show EIF4E Antibodies) axis.

  3. data suggest a physiological role for MNK1a-Ser (show SIGLEC1 Antibodies)(353) phosphorylation in regulation of the MNK1a kinase, which correlates with increased eIF4E (show EIF4E Antibodies) phosphorylation in vitro and in vivo.

  4. Data suggest MNK1/MNK2 (show MKNK2 Antibodies) stimulate mRNA translation but only of mRNA containing both 5-prime-terminal cap and hairpin duplex; this stimulation involves up-regulation of phosphorylation/mRNA un-winding activity of eIF4E (show EIF4E Antibodies) (via decreased binding to eIF4G (show EIF4G1 Antibodies)).

  5. Simultaneous targeting of androgen receptor (show AR Antibodies) and MNK1 by novel retinamides inhibits growth of human prostate cancer cell lines.

  6. MNK1 and MNK2 (show MKNK2 Antibodies) inhibition ablates eIF4E1 (show EIF4E Antibodies) phosphorylation and concurrently enhances eIF4E3 (show EIF4E3 Antibodies) expression in diffuse large B-cell lymphoma.

  7. Data show that interferon-gamma (show IFNG Antibodies) regulated the metabolism and mRNA translation of macrophages by targeting the kinases mTORC1 and MNK1/2, both of which converge on the selective regulator of translation initiation eukaryotic initiation factor-4E (eIF4E (show EIF4E Antibodies)).

  8. Data suggest that a combined pharmacologic inhibition of mTORC1 and Mnk1/2 kinases offers a therapeutic opportunity in blast crisis-chronic myeloid leukemia (BC-CML).

  9. Authors show that MNK (show ATP7A Antibodies) regulates SRPK (show SRPK1 Antibodies) via mTOR (show FRAP1 Antibodies) and AKT (show AKT1 Antibodies).

  10. ERK1/2 (show MAPK1/3 Antibodies) signal induced MNK (show ATP7A Antibodies) catalytic activity enabled enterovirus type 1 internal ribosomal entry site-mediated translation/host cell cytotoxicity through negative regulation of the Ser (show SIGLEC1 Antibodies)/Arg (SR)-rich protein kinase (show CDK7 Antibodies) (SRPK (show SRPK1 Antibodies)).

Mouse (Murine) MAP Kinase Interacting serine/threonine Kinase 1 (MKNK1) interaction partners

  1. Studies indicate that progesterone receptor (show PGR Antibodies) transgenic (Pgrcre/+) mitogen inducible gene 6 (Mig (show CXCL9 Antibodies)-6over) phosphatase and tensin homolog (show PTEN Antibodies) protein (Ptenf/f) knockout mice exhibited an increase of phospho-ERK1/2 (show MAPK1/3 Antibodies) and its target genes.

  2. Gpr182 reduction led to increased activation of ERK1/2 in basal and challenge models, demonstrating a potential role for this orphan GPCR in regulating the proliferative capacity of the intestine.

  3. ERK1 (show MAPK3 Antibodies) underexpression is associated with obesity.

  4. retinoschisin (show RS1 Antibodies) is a novel regulator of MAP kinase (show MAPK1 Antibodies) signalling and exerts an anti-apoptotic effect on retinal cells.

  5. Postnatal chondrocyte-specific deletion of Hdac3 (show HDAC3 Antibodies) with an inducible Col2a1 (show COL2A1 Antibodies)-Cre caused premature production of pErk1/2 and Mmp13 (show MMP13 Antibodies) in the growth plate.

  6. The progress of neurogenesis depended on sustained ERK (show EPHB2 Antibodies) phosphorylation and resulted in ERK1/2 (show MAPK1/3 Antibodies) translocation to the nucleus.

  7. Mirtazapine suppressed 5-HT (show DDC Antibodies)-mediated TGF-beta1 (show TGFB1 Antibodies)/Smad3 (show SMAD3 Antibodies) and ERK1/2 (show MAPK1/3 Antibodies) signaling pathways as well as oxidative stress that contribute to the progression of liver fibrosis.

  8. The kinase TPL2 (show MAP3K8 Antibodies) activates ERK (show EPHB2 Antibodies) and p38 (show CRK Antibodies) signaling to promote neutrophilic inflammation

  9. MNK1 participates in mediating high-fat diet-induced insulin (show INS Antibodies) resistance. Our findings reveal distinct roles for the MNKs in a novel area of disease biology

  10. HAS2 (show HAS2 Antibodies)-produced hyaluronan is required for CD44V6 and TGFbetaRI co-localization and subsequent CD44V6/ERK1 (show MAPK3 Antibodies)/EGR1 (show EGR1 Antibodies) signaling. These results demonstrate a novel positive-feedback loop that links the myofibroblast phenotype to TGFbeta1 (show TGFB1 Antibodies)-stimulated CD44V6/ERK (show EPHB2 Antibodies)/EGR1 (show EGR1 Antibodies) signaling.

MKNK1 Antigen Profile

Antigen Summary

This gene encodes a Ser/Thr protein kinase that interacts with, and is activated by ERK1 and p38 mitogen-activated protein kinases, and thus may play a role in the response to environmental stress and cytokines. This kinase may also regulate transcription by phosphorylating eIF4E via interaction with the C-terminal region of eIF4G. Alternatively spliced transcript variants have been noted for this gene.

Alternative names and synonyms associated with MKNK1

  • MAP kinase interacting serine/threonine kinase 1 (MKNK1) antibody
  • MAP kinase interacting serine/threonine kinase 1 (mknk1) antibody
  • MAP kinase-interacting serine/threonine kinase 1 (Mknk1) antibody
  • mitogen activated protein kinase 3 (Mapk3) antibody
  • mitogen-activated protein kinase 3 (Mapk3) antibody
  • 2410048M24Rik antibody
  • Erk-1 antibody
  • Erk1 antibody
  • Ert2 antibody
  • Esrk1 antibody
  • MAPK1 antibody
  • MKNK1 antibody
  • Mnk1 antibody
  • Mtap2k antibody
  • p44 antibody
  • p44erk1 antibody
  • p44mapk antibody
  • Prkm3 antibody
  • zgc:171912 antibody

Protein level used designations for MKNK1

MAP kinase interacting serine/threonine kinase 1 , MAP kinase-interacting serine/threonine-protein kinase 1 , MAP kinase signal-integrating kinase 1 , MAPK signal-integrating kinase 1 , mnk1 , MAP kinase 1 , MAP kinase 3 , MAP kinase isoform p44 , MAPK 1 , MAPK 3 , extracellular signal-regulated kinase 1 , insulin-stimulated MAP2 kinase , microtubule-associated protein 2 kinase , mitogen-activated 3 , mitogen-activated protein kinase 1 , mitogen-activated protein kinase 3 , p44 MAP kinase , pp42/MAP kinase

GENE ID SPECIES
469189 Pan troglodytes
555974 Danio rerio
771961 Gallus gallus
8569 Homo sapiens
525647 Bos taurus
17346 Mus musculus
500526 Rattus norvegicus
50689 Rattus norvegicus
26417 Mus musculus
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