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Human p38 ELISA Kit for Cell ELISA - ABIN1981835
Han, Lee, Bibbs, Ulevitch: A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells. in Science (New York, N.Y.) 1994
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Human p38 ELISA Kit for Sandwich ELISA - ABIN625229
Brenner, Rosenhagen, Brandt, Schmitt, Jung, Schemmer, Schmidt, Mieth, Bruckner, Lichtenstern, Martin, Weigand, Hofer: Cell death biomarkers as early predictors for hepatic dysfunction in patients after orthotopic liver transplantation. in Transplantation 2012
our results strongly indicate that the crosstalk between p38 (show CRK ELISA Kits) and Akt (show AKT1 ELISA Kits) pathways can determine special AT-rich sequence-binding protein 2 (show SATB2 ELISA Kits) expression and epithelial character of non-small-cell lung carcinoma cells
Osmotic stress promotes TEAD4 (show TEAD4 ELISA Kits) cytoplasmic translocation via p38 MAPK (show MAPK14 ELISA Kits) in a Hippo-independent manner. Stress-induced TEAD inhibition predominates YAP (show YAP1 ELISA Kits)-activating signals and selectively suppresses YAP (show YAP1 ELISA Kits)-driven cancer cell growth.
TGF-beta (show TGFB1 ELISA Kits) induces p38alpha (mitogen-activated protein kinase 14 (show MAPK14 ELISA Kits) [MAPK14 (show MAPK14 ELISA Kits)]), which in turn phosphorylates NR4A1 (show NR4A1 ELISA Kits), resulting in nuclear export of the receptor.
Data suggest that suppression of nonsense-mediated RNA decay due to persistent DNA damage (from exposure to either mutagens, gamma rays, or oxidative stress) requires the activity of p38alpha (show MAPK14 ELISA Kits) MAPK (show MAPK1 ELISA Kits) (MAPK14 (show MAPK14 ELISA Kits), mitogen-activated protein kinase 14 (show MAPK14 ELISA Kits), MAP kinase p38 alpha (show MAPK14 ELISA Kits)); mRNA of ATF3 (activating transcription factor 3 (show ATF3 ELISA Kits)) is stabilized by persistent DNA damage in a p38alpha (show MAPK14 ELISA Kits) MAPK (show MAPK1 ELISA Kits)-dependent manner.
VEGF (show VEGFA ELISA Kits)-activated p38alpha (show MAPK14 ELISA Kits) phosphorylates coronin 1B (show CORO1B ELISA Kits) at Ser2 (show JAG2 ELISA Kits) and activates the Arp2 (show ACTR2 ELISA Kits)/3 complex by liberating it from coronin 1B (show CORO1B ELISA Kits).
findings show that endothelial MAPKs ERK (show EPHB2 ELISA Kits), p38 (show CRK ELISA Kits), and JNK (show MAPK8 ELISA Kits) mediate diapedesis-related and diapedesis-unrelated functions of ICAM-1 (show ICAM1 ELISA Kits) in cerebral and dermal microvascular endothelial cells
Tetraarsenic hexoxide (As4O6) induced G2/M arrest, apoptosis and autophagic cell death through PI3K (show PIK3CA ELISA Kits)/Akt (show AKT1 ELISA Kits) and p38 MAPK (show MAPK14 ELISA Kits) pathways alteration in SW620 colon cancer cells.
The N-Terminal phosphorylation of RB by p38 (show CRK ELISA Kits) bypasses its inactivation by cyclin (show PCNA ELISA Kits)-dependent kinases and prevents proliferation in cancer cells.
Inhibition of MAPK14 (show MAPK14 ELISA Kits) conclusively facilitates elucidation of the impact of the complex network of p38 MAPK (show MAPK14 ELISA Kits) signaling on atherogenesis.
Collectively, this study provides more insights into RELT (show RELT ELISA Kits) expression, RELT (show RELT ELISA Kits) family member function, and the mechanism of RELT (show RELT ELISA Kits)-induced death.
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.