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Browse our anti-PAK2 (PAK2) Antibodies

Full name:
anti-P21-Activated Kinase 2 Antibodies (PAK2)
On are 174 P21-Activated Kinase 2 (PAK2) Antibodies from 25 different suppliers available. Additionally we are shipping PAK2 Proteins (11) and PAK2 Kits (10) and many more products for this protein. A total of 208 PAK2 products are currently listed.
5330420P17Rik, A130002K10Rik, AI836325, cb422, D16Ertd269e, gamma-PAK, kinase, mKIAA4182, PAK-2, pak2, Pak3, PAK65, PAKgamma, PAKI, si:dz198m22.1, wu:fb71h01, zgc:91798

Most Popular Reactivities for anti-PAK2 (PAK2) Antibodies

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anti-Human PAK2 Antibodies:

anti-Mouse (Murine) PAK2 Antibodies:

anti-Rat (Rattus) PAK2 Antibodies:

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Top referenced anti-PAK2 Antibodies

  1. Human Polyclonal PAK2 Primary Antibody for EIA, IHC (p) - ABIN500441 : Jaffer, Chernoff: p21-activated kinases: three more join the Pak. in The international journal of biochemistry & cell biology 2002 (PubMed)
    Show all 4 references for ABIN500441

  2. Human Polyclonal PAK2 Primary Antibody for EIA, IHC (p) - ABIN500439 : Ang, Patel, Yin, Sundaram, Fritchie, Zhao, Liu, Freemerman, Wilkerson, Walter, Weissler, Shockley, Couch, Zanation, Hackman, Chera, Harris, Miller, Thorne, Hayward, Funkhouser, Olshan, Shores, Makowski, Hayes: High XRCC1 protein expression is associated with poorer survival in patients with head and neck squamous cell carcinoma. in Clinical cancer research : an official journal of the American Association for Cancer Research 2011 (PubMed)
    Show all 4 references for ABIN500439

  3. Human Polyclonal PAK2 Primary Antibody for IHC (p), WB - ABIN392433 : Benner, Dennis, Masaracchia: Activation of an S6/H4 kinase (PAK 65) from human placenta by intramolecular and intermolecular autophosphorylation. in The Journal of biological chemistry 1995 (PubMed)
    Show all 2 references for ABIN392433

  4. Human Polyclonal PAK2 Primary Antibody for EIA, IHC (p) - ABIN360318 : Martin, Bollag, McCormick, Abo: A novel serine kinase activated by rac1/CDC42Hs-dependent autophosphorylation is related to PAK65 and STE20. in The EMBO journal 1995 (PubMed)
    Show all 2 references for ABIN360318

  5. Human Monoclonal PAK2 Primary Antibody for ICC, IHC - ABIN969338 : Chu, Wu, Liao, Pardo, Zhao, Li, Mendenhall, Pali, Shen, Yu, Taylor, Aversa, Molineaux, Payan, Masuda: A novel role for p21-activated protein kinase 2 in T cell activation. in Journal of immunology (Baltimore, Md. : 1950) 2004 (PubMed)
    Show all 2 references for ABIN969338

  6. Human Polyclonal PAK2 Primary Antibody for IHC (p), WB - ABIN318772 : Roig, Traugh: Cytostatic p21 G protein-activated protein kinase gamma-PAK. in Vitamins and hormones 2001 (PubMed)
    Show all 2 references for ABIN318772

  7. Human Polyclonal PAK2 Primary Antibody for ELISA, WB - ABIN1533101 : Olsen, Blagoev, Gnad, Macek, Kumar, Mortensen, Mann: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. in Cell 2006 (PubMed)

More Antibodies against PAK2 Interaction Partners

Zebrafish P21-Activated Kinase 2 (PAK2) interaction partners

  1. EphrinB ligands B2a and B3b, the Ephb4a (show EPHB4 Antibodies) receptor and the Pak2a kinase are required for the development of pharyngeal pouches and the segmentation of the posterior facial skeleton.

  2. Essential in vivo role for betaPix (show ARHGEF7 Antibodies) and Pak2a during embryonic development and a previously unrecognized pathway specifically involved in cerebrovascular stabilization. [BetaPix (show ARHGEF7 Antibodies) AND Pak2a]

  3. Data provide evidence for a critical function of Pak2 in vascular integrity and demonstrate a severe disease phenotype resulting from loss of Pak2 function.

Human P21-Activated Kinase 2 (PAK2) interaction partners

  1. PAK2 is a direct effector of TSC1 (show TSC1 Antibodies)-TSC2 (show TSC2 Antibodies)-RHEB (show RHEB Antibodies) signaling and a new target for rational drug therapy in TSC (show SLC12A3 Antibodies).

  2. Nef exploits PAK2 in a stepwise mechanism in which its kinase activity cooperates with an adaptor function for the exocyst complex to inhibit host cell actin dynamics.

  3. Cytoplasmic Pak2 may promote cell proliferation in normal endometrium during menstrual cycle.

  4. Further analyses show that HDAC6 (show HDAC6 Antibodies) may promote growth of GBM cells through inhibition of SMAD2 (show SMAD2 Antibodies) phosphorylation to downregulate p21 (show CDKN1A Antibodies)

  5. Pak1 (show PAK1 Antibodies) and Pak2 counteract centrosome separation in a kinase-dependent manner.

  6. Findings indicate that repression of microRNA miR (show MLXIP Antibodies)-134 and consequent up-regulation of p21-activated kinase 2 (Pak2) might contribute to paclitaxel resistance.

  7. Inhibition of PAK activation at late G2-phase centrosomes caused by Rac1 inactivation coincides with impeded activation of Aurora A (show AURKA Antibodies) and the CyclinB (show CCNB1 Antibodies)/Cdk1 (show CDK1 Antibodies) complex and delayed mitotic entry.

  8. Data show that group I p21 (show CDKN1A Antibodies)-activated kinases (Paks) Pak1 (show PAK1 Antibodies) and Pak2 were much more abundant than Pak3 in meningioma.

  9. Results identified Pak2 as a possibly important mediator of ovarian cancer cell migration on extracellular matrix.

  10. PAK2 activation may be associated with advanced tumor progression and poor prognosis of gastric cancer

Mouse (Murine) P21-Activated Kinase 2 (PAK2) interaction partners

  1. Pak2 disruption decreased the survival and proliferation of multicytokine stimulated immature progenitors.

  2. The data suggest that Pak2 controls thymic Natural Killer T-cell development by providing a signal that links Egr2 (show EGR2 Antibodies) to induce PLZF (show ZBTB16 Antibodies), in part by regulating signaling lymphocyte activation molecule (show SLAMF1 Antibodies) 6 expression.

  3. In adult endothelial cells, Pak2 depletion leads to severe apoptosis and acute angiogenesis defects, and in adult mice, endothelial Pak2 deletion leads to increased vascular permeability.

  4. Pak2 Links TCR Signaling Strength to the Development of Regulatory T Cells and Maintains Peripheral Tolerance

  5. Failure to induce proper actin cytoskeletal remodeling impaired PLCgamma1 and Erk1/2 signaling in the absence of Pak2, uncovering the critical function of Pak2 as an essential regulator that governs the actin cytoskeleton-dependent signaling

  6. thrombin (show F2 Antibodies) induces monocyte/macrophage migration via PAR1 (show F2R Antibodies)-Galpha12 (show GNA12 Antibodies)-dependent Pyk2 (show PTK2B Antibodies)-mediated Gab1 (show GAB1 Antibodies) and p115 RhoGEF (show ARHGEF1 Antibodies) interactions, leading to Rac1- and RhoA (show RHOA Antibodies)-targeted Pak2 activation.

  7. p21 (show D4S234E Antibodies)-activated kinase is essential for hematopoietic stem/progenitor cell migration and engraftment.

  8. Pak2, but not Pak1 (show PAK1 Antibodies), negatively regulates RhoA (show RHOA Antibodies) via phosphorylation of the guanine nucleotide exchange factor (show ARHGEF12 Antibodies) GEF-H1 (show ARHGEF2 Antibodies) at an inhibitory site, leading to increased GEF-H1 (show ARHGEF2 Antibodies) microtubule binding and loss of RhoA (show RHOA Antibodies) stimulation

  9. Full-length PAK-2 rather than the caspase-activated PAK-2p34 is required for normal embryonic development.

  10. phosphorylation of merlin (show NF2 Antibodies) at serine 518 is induced by the p21 (show D4S234E Antibodies)-activated kinase PAK2

Cow (Bovine) P21-Activated Kinase 2 (PAK2) interaction partners

  1. Basement membrane proteins promote PAK2 Ser (show SIGLEC1 Antibodies)-20 phosphorylation through enhanced eNOS (show NOS3 Antibodies) activation and NO production.

PAK2 Antigen Profile

Antigen Summary

The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. The protein encoded by this gene is activated by proteolytic cleavage during caspase-mediated apoptosis, and may play a role in regulating the apoptotic events in the dying cell.

Alternative names and synonyms associated with PAK2

  • p21 (CDKN1A)-activated kinase 2a (pak2a) antibody
  • p21 protein (Cdc42/Rac)-activated kinase 2 (pak2) antibody
  • p21 protein (Cdc42/Rac)-activated kinase 2 (PAK2) antibody
  • p21 protein (Cdc42/Rac)-activated kinase 2 (Pak2) antibody
  • 5330420P17Rik antibody
  • A130002K10Rik antibody
  • AI836325 antibody
  • cb422 antibody
  • D16Ertd269e antibody
  • gamma-PAK antibody
  • kinase antibody
  • mKIAA4182 antibody
  • PAK-2 antibody
  • pak2 antibody
  • Pak3 antibody
  • PAK65 antibody
  • PAKgamma antibody
  • PAKI antibody
  • si:dz198m22.1 antibody
  • wu:fb71h01 antibody
  • zgc:91798 antibody

Protein level used designations for PAK2

p21 (CDKN1A)-activated kinase 2 , p21-activated kinase 2 , redhead , rhd , serine/threonine-protein kinase PAK 2 , p21 activated kinase 2 , PAK-2 , S6/H4 kinase , gamma-PAK , p58 , p21-activated kinase I , p21-activated protein kinase I

266749 Danio rerio
399090 Xenopus laevis
460965 Pan troglodytes
5062 Homo sapiens
224105 Mus musculus
29432 Rattus norvegicus
513673 Bos taurus
612814 Canis lupus familiaris
424860 Gallus gallus
100009535 Oryctolagus cuniculus
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