anti-Rat (Rattus) PAK2 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended PAK2 Antibody (supplied by: Log in to see )

Antigen
P21-Activated Kinase 2 (PAK2) Antibodies
  • pak2
  • cb422
  • kinase
  • zgc:91798
  • wu:fb71h01
  • si:dz198m22.1
  • pak65
  • pakgamma
  • PAK65
  • PAKgamma
  • 5330420P17Rik
  • A130002K10Rik
  • AI836325
  • D16Ertd269e
  • PAK-2
  • mKIAA4182
  • gamma-PAK
  • PAKI
  • Pak3
  • p21 (CDKN1A)-activated kinase 2a
  • p21 protein (Cdc42/Rac)-activated kinase 2
  • pak2a
  • pak2
  • PAK2
  • Pak2
Reactivity
Human, Mouse (Murine), Rat (Rattus)
183
96
91
12
8
1
Host
Rabbit
164
19
Clonality
Polyclonal
Conjugate
This PAK2 antibody is un-conjugated
4
4
4
4
4
4
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
164
101
76
35
19
6
6
4
3
2
2
1
Supplier
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Catalog No. ABIN499019
$ 390.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
13.399764 ABIN213961 IHC (p) WB Rabbit N-Term Log in to see Polyclonal
13.399764 ABIN214460 IHC (p) WB Rabbit C-Term Log in to see Polyclonal
13.399764 ABIN4343470 ELISA ICC IF IHC IHC (p) WB Rabbit C-Term Log in to see Polyclonal
13.399764 ABIN4343471 ELISA ICC IF IHC IHC (p) WB Rabbit N-Term Log in to see Polyclonal
13.399764 ABIN4343467 IHC IHC (p) WB Rabbit Log in to see Polyclonal
1 ABIN318772 IHC (p) WB Rabbit IgG C-Term Log in to see Polyclonal 2
1 ABIN5555094 EIA IHC (p) WB Rabbit IgG C-Term Log in to see Polyclonal
1 ABIN5555095 EIA IHC (p) WB Rabbit IgG N-Term Log in to see Polyclonal
1 ABIN2476049 IHC (p) WB Rabbit IgG C-Term Log in to see Polyclonal 3
1 ABIN303230 IHC (p) WB Rabbit C-Term Log in to see Polyclonal
1 ABIN302844 IHC (p) WB Rabbit Log in to see Polyclonal
1 ABIN127122 IHC (p) WB Rabbit Log in to see Polyclonal
1 ABIN1737829 IHC (p) WB Rabbit IgG Log in to see Polyclonal
1 ABIN1737828 IHC (p) WB Rabbit IgG Log in to see Polyclonal
1 ABIN744518 IF (p) IHC (p) WB Rabbit IgG pSer20 Log in to see Polyclonal
1 ABIN747563 IF (p) IHC (p) WB Rabbit IgG Log in to see Polyclonal
1 ABIN2884190 ELISA IHC (p) WB Rabbit IgG pSer20 Log in to see Polyclonal
1 ABIN2884189 ELISA IHC (p) Rabbit IgG pSer197 Log in to see Polyclonal
1 ABIN2884186 ELISA IHC (p) Rabbit IgG AA 5-54 Log in to see Polyclonal
1 ABIN2893092 IHC (p) WB Rabbit Arg186 Log in to see Polyclonal

Top referenced anti-PAK2 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Similar anti-PAK2 Antibodies

Application / Reactivity Human Mouse (Murine) Rat (Rattus)
Immunofluorescence (fixed cells) (IF/ICC) 4 Antibodies 1 Antibodies 1 Antibodies
Western Blotting (WB) 165 Antibodies 82 Antibodies 78 Antibodies
Proximity Ligation Assay (PLA) 1 Antibodies
Immunoprecipitation (IP) 6 Antibodies 4 Antibodies 1 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 36 Antibodies 24 Antibodies 23 Antibodies
Immunohistochemistry (IHC) 76 Antibodies 38 Antibodies 38 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 2 Antibodies

General

Antigen P21-Activated Kinase 2 (PAK2) Antibodies
Reactivity Human, Mouse (Murine), Rat (Rattus)
(183), (96), (91), (12), (8), (1)
Host Rabbit
(164), (19)
Clonality
Polyclonal
Conjugate This PAK2 antibody is un-conjugated
(4), (4), (4), (4), (4), (4)
Application Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(164), (101), (76), (35), (19), (6), (6), (4), (3), (2), (2), (1)
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Product Details anti-PAK2 Antibody

Target Details PAK2 Application Details Handling Images
Specificity This antibody detects endogenous levels of PAKγ protein. (region surrounding Arg186)
Cross-Reactivity (Details) Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.
Purification Affinity chromatography
Purity > 95 % by SDS-PAGE

Target Details PAK2

Product Details anti-PAK2 Antibody Application Details Handling Images back to top
Antigen
Alternative Name PAK2 (PAK2 Antibody Abstract)
Background Three isoforms of serine/threonine kinases, designated 7PAK p68, 8PAK p65 and 9PAK p62, have been shown to exhibit a high degree of sequence homology with the S. cerevisiae kinase Ste 20, involved in pheromone signaling. The 7, 8, and 9 PAK isoforms complex specifically with Rac1 and Cdc42 in their active GTP-bound state, inhibiting their intrinsic GTPase activity leading to their autophosphorylation. There are eight sites of autophosphorylation on 9 PAK, including Ser 19, Ser 141 Thr 402, phosphorylation of Ser 141 and Thr 402 is correlated with 9 PAK activation. Once phosphorylated and their affinity for Rac/Cdc42 reduced, the PAK isoforms disassociate from the complex to seek downstream substrates. One such putative substrate is Mek kinase, an upstream effector of Mek4, which is involved in the JNK signaling pathway. While the PAK isoforms interact in a GTP dependent manner with Rac 1 and Cdc 42, they do not interact with Rho.Synonyms: Gamma-PAK, PAK 2, PAK gamma, PAK-2, PAK65, Serine/threonine-protein kinase PAK 2, p21-activated kinase 2, p58
Molecular Weight approx. 58 kDa
Gene ID 5062
NCBI Accession NP_002568
UniProt Q13177
Research Area Cancer, Apoptosis/Necrosis, Tyrosine Kinases, Kinases/Phosphatases
Pathways MAPK Signaling, RTK Signaling, TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha

Application Details

Product Details anti-PAK2 Antibody Target Details PAK2 Handling Images back to top
Application Notes Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-PAK2 Antibody Target Details PAK2 Application Details Images back to top
Concentration 1,0 mg/mL
Buffer Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Images

Product Details anti-PAK2 Antibody Target Details PAK2 Application Details Handling back to top
Supplier Images
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-PAK2 antibody (P21-Activated Kinase 2) (ABIN499019) Immunohistochemistry (IHC) analyzes of PAKγ antibody in paraffin-embedded huma...
Western Blotting (WB) image for anti-PAK2 antibody (P21-Activated Kinase 2) (ABIN499019) Western blot (WB) analysis of PAKγ antibody in extracts from PC12 ce...