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Browse our anti-Paxillin (PXN) Antibodies

Full name:
anti-Paxillin Antibodies (PXN)
On www.antibodies-online.com are 385 Paxillin (PXN) Antibodies from 27 different suppliers available. Additionally we are shipping Paxillin Kits (44) and Paxillin Proteins (15) and many more products for this protein. A total of 466 Paxillin products are currently listed.
Synonyms:
AW108311, AW123232, CG18061, CG18576, CG31794, CT40481, CT42454, Dmel\\CG31794, dPax, DpaxA, DPaxillin, DPxn, DPxn37, LOC100220858, Pax, PDLP, PXN, wu:fw71f12

All available anti-Paxillin Antibodies

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Top referenced anti-Paxillin Antibodies

  1. Chicken Monoclonal Paxillin Primary Antibody for IHC (f), IF - ABIN967711 : Even-Ram, Maoz, Pokroy, Reich, Katz, Gutwein, Altevogt, Bar-Shavit: Tumor cell invasion is promoted by activation of protease activated receptor-1 in cooperation with the alpha vbeta 5 integrin. in The Journal of biological chemistry 2001 (PubMed)
    Show all 5 references for ABIN967711

  2. Chicken Monoclonal Paxillin Primary Antibody for BI, IP - ABIN968043 : Ku, Meier: Phosphorylation of paxillin via the ERK mitogen-activated protein kinase cascade in EL4 thymoma cells. in The Journal of biological chemistry 2000 (PubMed)
    Show all 5 references for ABIN968043

  3. Chicken Monoclonal Paxillin Primary Antibody for BI, IP - ABIN968042 : Salgia, Li, Lo, Brunkhorst, Kansas, Sobhany, Sun, Pisick, Hallek, Ernst: Molecular cloning of human paxillin, a focal adhesion protein phosphorylated by P210BCR/ABL. in The Journal of biological chemistry 1995 (PubMed)
    Show all 5 references for ABIN968042

  4. Human Polyclonal Paxillin Primary Antibody for IHC (p), WB - ABIN196776 : Tao, Wollscheid, OBrien, Eng, Li, Bodenmiller, Watts, Hood, Aebersold: Quantitative phosphoproteome analysis using a dendrimer conjugation chemistry and tandem mass spectrometry. in Nature methods 2005 (PubMed)
    Show all 4 references for ABIN196776

  5. Human Polyclonal Paxillin Primary Antibody for IF, WB - ABIN401644 : Bellis, Miller, Turner: Characterization of tyrosine phosphorylation of paxillin in vitro by focal adhesion kinase. in The Journal of biological chemistry 1995 (PubMed)
    Show all 4 references for ABIN401644

  6. Chicken Monoclonal Paxillin Primary Antibody for IF, IP - ABIN968066 : Laukaitis, Webb, Donais, Horwitz: Differential dynamics of alpha 5 integrin, paxillin, and alpha-actinin during formation and disassembly of adhesions in migrating cells. in The Journal of cell biology 2001 (PubMed)
    Show all 4 references for ABIN968066

  7. Human Monoclonal Paxillin Primary Antibody for IF, IHC (p) - ABIN180343 : de Curtis, Malanchini: Integrin-mediated tyrosine phosphorylation and redistribution of paxillin during neuronal adhesion. in Experimental cell research 1997 (PubMed)
    Show all 3 references for ABIN180343

  8. Human Polyclonal Paxillin Primary Antibody for IHC (p), WB - ABIN197278 : Zhang, Wolf-Yadlin, Ross, Pappin, Rush, Lauffenburger, White: Time-resolved mass spectrometry of tyrosine phosphorylation sites in the epidermal growth factor receptor signaling network reveals dynamic modules. in Molecular & cellular proteomics : MCP 2005 (PubMed)
    Show all 3 references for ABIN197278

  9. Human Polyclonal Paxillin Primary Antibody for IHC (p), WB - ABIN197424 : Davidson, Veillette: PTP-PEST, a scaffold protein tyrosine phosphatase, negatively regulates lymphocyte activation by targeting a unique set of substrates. in The EMBO journal 2001 (PubMed)
    Show all 3 references for ABIN197424

  10. Chicken Monoclonal Paxillin Primary Antibody for IF, WB - ABIN1108595 : Turner, Glenney, Burridge: Paxillin: a new vinculin-binding protein present in focal adhesions. in The Journal of cell biology 1990 (PubMed)
    Show all 2 references for ABIN1108595

More Antibodies against Paxillin Interaction Partners

Fruit Fly (Drosophila melanogaster) Paxillin (PXN) interaction partners

  1. Data indicate that tramtrack69 regulates ovary epithelial tube morphogenesis through Paxillin, Dynamin (show DNM1 Antibodies), and the homeobox protein (show HOXA1 Antibodies) Mirror.

  2. New insights from hemichordate genomes: prebilaterian origin and parallel modifications in the paired domain of the Pax gene eyegone

  3. Results identify a link between the focal adhesion protein paxillin and the Atg1 (show ULK1 Antibodies) kinase, which has been previously implicated in autophagy.

  4. Data show that Pax genes are involved in the development of the anterior/posterior brain boundary zone during embryonic CNS development in Drosophila.

Human Paxillin (PXN) interaction partners

  1. Data suggest that, in colonic/prostatic neoplasm cells, increased expression of NDRG1 decreases activating phosphorylation of FAK and paxillin; silencing/inhibition of NDRG1 results in opposite effect and inhibits neoplasm cell migration/adhesion.

  2. These findings suggest that PXN expression has potential use as a novel biomarker of laryngeal squamous cell carcinoma patients and may serve as an independent predictive factor for prognosis.

  3. Mode of Action of Functionally Important Regions in the Intrinsically Disordered Paxillin

  4. Paxillin was expressed at significantly higher levels in colorectal cancer tissues and might serve as a potential prognostic indicator in patients with colorectal cancer

  5. these data suggested that miR (show MLXIP Antibodies)-145 plays a pivotal role in colon cancer through inhibiting cell proliferation migration and invasion, and miR (show MLXIP Antibodies)-145 may serve as a tumor suppressor by targeting paxillin gene.

  6. In colorectal cancers PXN was positively correlated with Bcl-2 (show BCL2 Antibodies), pBcl-2-S87, and MMP2 (show MMP2 Antibodies) expression. PXN promotes Bcl-2 (show BCL2 Antibodies) phosphorylation at Serine 87 via ERK (show EPHB2 Antibodies) activation, increases xenograft tumor formation, and associates with poor patient outcome.

  7. Bcl-2 (show BCL2 Antibodies) stabilization by paxillin confers 5-fluorouracil resistance in colorectal cancer.

  8. Fascin-1 (show FSCN1 Antibodies) and paxillin were expressed in 58% and 43% of infiltrating duct carcinoma cases. There was a significant correlation between fascin-1 (show FSCN1 Antibodies) and paxillin expression and tumor grade, clinical stage, lymph-node metastasis grade, and HER2 (show ERBB2 Antibodies) expression.

  9. Suggest paxillin up-regulation and phosphorylation as an important mechanism of vascular remodelling underlying pulmonary hypertension.

  10. During early cell spreading, DLC1 (show DYNLL1 Antibodies) is preferentially localized at the inner/mature adhesions whereas phosphorylated paxillin occupies the outer/nascent focal adhesions. In addition, DLC1 (show DYNLL1 Antibodies) downregulates paxillin turnover

Mouse (Murine) Paxillin (PXN) interaction partners

  1. Lithium therapy abrogated GSK3beta overactivity, blunted paxillin hyperphosphorylation, and reinstated actin cytoskeleton integrity in glomeruli associated with an early attenuation of podocyte foot process effacement.

  2. Suggest paxillin up-regulation and phosphorylation as an important mechanism of vascular remodelling underlying pulmonary hypertension.

  3. LPS-induced paxillin phosphorylation at Y31 and Y118 was mediated by c-Abl tyrosine kinase

  4. Study provides evidence that phosphorylation of PXN is required for cisplatin resistance in lung cancer cells.

  5. MELK (show MELK Antibodies) promotes cell migration and invasion via the FAK (show PTK2 Antibodies)/Paxillin pathway, and plays an important role in the occurrence and development of gastric cancer.

  6. FAK (show PTK2 Antibodies)-paxillin interactions are indispensable for cell adhesion, migration and invasion processes.

  7. paxillin and zyxin (show ZYX Antibodies) are LIM (show PDLIM5 Antibodies)-domain adaptor proteins that are recruited to stress fiber strain sites

  8. Data indicate that CD45 (show PTPRC Antibodies) functions to regulate Pyk2 (show PTK2B Antibodies)/FAK (show PTK2 Antibodies) activity, likely through the activity of Src (show SRC Antibodies) family kinases, which in turn regulates the levels of paxillin to modulate macrophage adhesion and migration.

  9. SLK (show SLK Antibodies) phosphorylates the adhesion adapter protein (show GRB10 Antibodies) paxillin on serine 250. Serine 250 phosphorylation is required for paxillin redistribution and cell motility.

  10. Paxillin is critical for integrating physical cues from the ECM (show MMRN1 Antibodies) with chemical motility signals by spatially constraining where cells form motile processes, and thereby regulates directional migration.

Zebrafish Paxillin (PXN) interaction partners

  1. paxillin may function in adhesion during the morphogenesis of the early zebrafish embryo

Xenopus laevis Paxillin (PXN) interaction partners

  1. Paxillin has a role in meiosis and may be a general modulator of mitogen-activated protein kinase (show MAPK1 Antibodies) signaling

  2. RING finger protein (show TRIM31 Antibodies) XRNF185 (show RNF185 Antibodies), which physically binds to paxillin and the proteasome. XRNF185 (show RNF185 Antibodies) destabilizes paxillin at focal adhesions and promotes mesodermal cell migration during convergent extension.

Pig (Porcine) Paxillin (PXN) interaction partners

  1. Role of Y118 paxillin phosphorylation and stimulated actin polymerization in carotid artery contraction.

Paxillin (PXN) Antigen Profile

Antigen Summary

This gene encodes a cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Alternatively spliced transcript variants encoding different isoforms have been described for this gene. These isoforms exhibit different expression pattern, and have different biochemical, as well as physiological properties (PMID:9054445).

Alternative names and synonyms associated with Paxillin (PXN)

  • paxillin (PXN) antibody
  • Paxillin (Pax) antibody
  • paxillin (pxn) antibody
  • paxillin (LOC100220858) antibody
  • paxillin (Pxn) antibody
  • paxillin-like (LOC100353305) antibody
  • AW108311 antibody
  • AW123232 antibody
  • CG18061 antibody
  • CG18576 antibody
  • CG31794 antibody
  • CT40481 antibody
  • CT42454 antibody
  • Dmel\\CG31794 antibody
  • dPax antibody
  • DpaxA antibody
  • DPaxillin antibody
  • DPxn antibody
  • DPxn37 antibody
  • LOC100220858 antibody
  • Pax antibody
  • PDLP antibody
  • PXN antibody
  • wu:fw71f12 antibody

Protein level used designations for anti-Paxillin (PXN) Antibodies

CG31794-PA , CG31794-PB , CG31794-PC , CG31794-PD , CG31794-PF , CG31794-PG , CG31794-PH , CG31794-PJ , CG31794-PK , D-Paxillin , Pax-PA , Pax-PB , Pax-PC , Pax-PD , Pax-PF , Pax-PG , Pax-PH , Pax-PJ , Pax-PK , Paxillin-derived LIM-only protein , paxillin , myocardial ischemic preconditioning associated protein 7

GENE ID SPECIES
100053811 Equus caballus
35215 Drosophila melanogaster
452303 Pan troglodytes
696336 Macaca mulatta
100216044 Xenopus (Silurana) tropicalis
100220858 Taeniopygia guttata
100474505 Ailuropoda melanoleuca
5829 Homo sapiens
19303 Mus musculus
360820 Rattus norvegicus
395832 Gallus gallus
517456 Bos taurus
399546 Danio rerio
397826 Xenopus laevis
486299 Canis lupus familiaris
100732427 Cavia porcellus
100126846 Sus scrofa
100173313 Pongo abelii
100353305 Oryctolagus cuniculus
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