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anti-Mouse (Murine) Paxillin antibody for Intracellular Flow Cytometry

Recommended Paxillin Antibody (supplied by: Log in to see )

Antigen
Paxillin (PXN) Antibodies
  • AW108311
  • AW123232
  • CG18061
  • CG18576
  • CG31794
  • CT40481
  • CT42454
  • Dmel\\CG31794
  • dPax
  • Dpax
  • DpaxA
  • DPaxillin
  • DPxn
  • DPxn37
  • LOC100220858
  • pax
  • Pax
  • PDLP
  • PXN
  • wu:fw71f12
Reactivity
Human, Mouse (Murine)
366
163
150
25
6
4
3
3
2
1
1
1
1
1
Host
Mouse
333
47
2
Clonality
Monoclonal
Conjugate
This Paxillin antibody is un-conjugated
7
7
7
5
5
5
5
5
5
5
5
5
2
2
2
1
1
Application
Intracellular Flow Cytometry (ICFC)
292
102
91
56
47
46
26
22
8
8
4
2
2
1
1
Supplier
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Catalog No. ABIN2666109
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Top referenced anti-Paxillin antibody for Intracellular Flow Cytometry

Similar anti-Paxillin Antibodies

Application / Reactivity Human Mouse (Murine)
Western Blotting (WB) 286 Antibodies 114 Antibodies
Proximity Ligation Assay (PLA) 1 Antibodies
Intracellular Flow Cytometry (ICFC) 1 Antibodies 1 Antibodies
Immunoprecipitation (IP) 23 Antibodies 11 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 47 Antibodies 24 Antibodies
Immunohistochemistry (IHC) 102 Antibodies 43 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 6 Antibodies 3 Antibodies
Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) 4 Antibodies 2 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 56 Antibodies 45 Antibodies
Immunofluorescence (IF) 47 Antibodies 10 Antibodies
Immunocytochemistry (ICC) 18 Antibodies

General

Antigen Paxillin (PXN) Antibodies
Reactivity Human, Mouse (Murine)
(366), (163), (150), (25), (6), (4), (3), (3), (2), (1), (1), (1), (1), (1)
Host Mouse
(333), (47), (2)
Clonality (Clone)
Monoclonal   ( )
Conjugate This Paxillin antibody is un-conjugated
(7), (7), (7), (5), (5), (5), (5), (5), (5), (5), (5), (5), (2), (2), (2), (1), (1)
Application Intracellular Flow Cytometry (ICFC)
(292), (102), (91), (56), (47), (46), (26), (22), (8), (8), (4), (2), (2), (1), (1)
Pubmed 7 references available
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Product Details anti-Paxillin Antibody

Target Details Paxillin Application Details Handling References for anti-Paxillin Antibody (ABIN2666109) Images
Purification The antibody was purified by affinity chromatography.
Clone PAX227
Isotype IgG1 kappa

Target Details Paxillin

Product Details anti-Paxillin Antibody Application Details Handling References for anti-Paxillin Antibody (ABIN2666109) Images back to top
Antigen
Alternative Name Paxillin (PXN Antibody Abstract)
Background Paxillin (also known as peroxisomal membrane protein 3) is a cytoplasmic protein with LIM metal-binding repeat homology and LIM domains. There are three isoforms of this protein designated as α, β, γ, approximate molecular weight 68 kD. Paxillin is localized to actin-membrane attachment at sites of cell adhesion to extracellular matrix (focal adhesion). This protein undergoes cell adhesion-dependent tyrosine phosphorylation. Paxillin has been shown to interact with FAK, vinculin, src, Crk, p210BRC / ABL, talin, and integrin-β1. The PAX227 monoclonal antibody recognizes human and mouse paxillin and has been shown to be useful for Western blotting.
Research Area Cancer, Extracellular Matrix
Pathways MAPK Signaling, EGFR Signaling Pathway

Application Details

Product Details anti-Paxillin Antibody Target Details Paxillin Handling References for anti-Paxillin Antibody (ABIN2666109) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-Paxillin Antibody Target Details Paxillin Application Details References for anti-Paxillin Antibody (ABIN2666109) Images back to top
Format Liquid
Buffer phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 50 % glycerol.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Upon receipt, store frozen at -20°C.

References for anti-Paxillin Antibody (ABIN2666109)

Product Details anti-Paxillin Antibody Target Details Paxillin Application Details Handling Images back to top
Background publications

Cai, Casimir, Schroer, Luk, Shi, Choi, Dai, Hajmrle, Spigelman, Zhu, Gaisano, MacDonald, Woo: "In vivo role of focal adhesion kinase in regulating pancreatic β-cell mass and function through insulin signaling, actin dynamics, and granule trafficking." in: Diabetes, Vol. 61, Issue 7, pp. 1708-18, 2012

Heinhuis, Koenders, van den Berg, Netea, Dinarello, Joosten: "Interleukin 32 (IL-32) contains a typical ?-helix bundle structure that resembles focal adhesion targeting region of focal adhesion kinase-1." in: The Journal of biological chemistry, Vol. 287, Issue 8, pp. 5733-43, 2012

Yao, Dashner, van Golen, van Golen: "RhoC GTPase is required for PC-3 prostate cancer cell invasion but not motility." in: Oncogene, Vol. 25, Issue 16, pp. 2285-96, 2006

Tang, Tan: "Role of Crk-associated substrate in the regulation of vascular smooth muscle contraction." in: Hypertension, Vol. 42, Issue 4, pp. 858-63, 2003

Kirchner, Kam, Tzur, Bershadsky, Geiger: "Live-cell monitoring of tyrosine phosphorylation in focal adhesions following microtubule disruption." in: Journal of cell science, Vol. 116, Issue Pt 6, pp. 975-86, 2003

Leventhal, Shelden, Kim, Feldman: "Tyrosine phosphorylation of paxillin and focal adhesion kinase during insulin-like growth factor-I-stimulated lamellipodial advance." in: The Journal of biological chemistry, Vol. 272, Issue 8, pp. 5214-8, 1997

Mazaki, Hashimoto, Sabe: "Monocyte cells and cancer cells express novel paxillin isoforms with different binding properties to focal adhesion proteins." in: The Journal of biological chemistry, Vol. 272, Issue 11, pp. 7437-44, 1997

Images

Product Details anti-Paxillin Antibody Target Details Paxillin Application Details Handling References for anti-Paxillin Antibody (ABIN2666109) back to top
Supplier Images
Immunofluorescence (IF) image for anti-Paxillin antibody (PXN) (ABIN2666109) anti-Paxillin (PXN) antibody
Western Blotting (WB) image for anti-Paxillin antibody (PXN) (ABIN2666109) anti-Paxillin (PXN) antibody (Image 2)