anti-Human RGS1 antibody for Enzyme Immunoassay

Recommended RGS1 Antibody (supplied by: Log in to see )

Antigen
Regulator of G-Protein Signaling 1 (RGS1) Antibodies
  • Gm202
  • Rgsl2
  • 4930415K13Rik
  • RGS1
  • 1R20
  • BL34
  • IER1
  • IR20
  • 1r20
  • bl34
  • ier1
  • ir20
  • regulator of G-protein signaling like 1
  • regulator of G-protein signaling 1
  • Rgsl1
  • RGS1
  • Rgs1
  • rgs1
Epitope
N-Term
24
17
9
8
7
4
4
4
2
2
2
1
1
1
1
1
Reactivity
Human
91
30
26
7
7
4
2
2
1
1
1
Host
Rabbit
65
20
4
2
Clonality
Polyclonal
Conjugate
This RGS1 antibody is un-conjugated
3
3
3
3
3
3
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
83
46
19
17
6
3
2
1
1
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Catalog No. ABIN453811
$ 390.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN5552756 EIA IHC (p) WB Goat C-Term Log in to see Polyclonal

General

Antigen Regulator of G-Protein Signaling 1 (RGS1) Antibodies
Epitope N-Term
(24), (17), (9), (8), (7), (4), (4), (4), (2), (2), (2), (1), (1), (1), (1), (1)
Reactivity Human
(91), (30), (26), (7), (7), (4), (2), (2), (1), (1), (1)
Host Rabbit
(65), (20), (4), (2)
Clonality
Polyclonal
Conjugate This RGS1 antibody is un-conjugated
(3), (3), (3), (3), (3), (3)
Application Enzyme Immunoassay (EIA), Western Blotting (WB)
(83), (46), (19), (17), (6), (3), (2), (1), (1)
Pubmed 1 reference available
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Product Details anti-RGS1 Antibody

Target Details RGS1 Application Details Handling References for anti-RGS1 antibody (ABIN453811) Images
Specificity This antibody reacts to RGS1.
Purification Affinity chromatography on Protein A
Immunogen KLH conjugated synthetic peptide selected from the N-term region of human RGS1

Target Details RGS1

Product Details anti-RGS1 Antibody Application Details Handling References for anti-RGS1 antibody (ABIN453811) Images back to top
Antigen
Alternative Name RGS1 (RGS1 Antibody Abstract)
Background RGS1 is a member of the regulator of G-protein signalling family. This protein is located on the cytosolic side of the plasma membrane and contains a conserved, 120 amino acid motif called the RGS domain. The protein attenuates the signalling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal.Synonyms: 1R20, B-cell activation protein BL34, BL34, Early response protein 1R20, IER1, Regulator of G-protein signaling 1
Gene ID 5996
NCBI Accession NP_002913
UniProt Q08116
Research Area Signaling, Immunology
Pathways MAPK Signaling, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, CXCR4-mediated Signaling Events

Application Details

Product Details anti-RGS1 Antibody Target Details RGS1 Handling References for anti-RGS1 antibody (ABIN453811) Images back to top
Application Notes ELISA: 1/1,000. Western blotting: 1/100 - 1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-RGS1 Antibody Target Details RGS1 Application Details References for anti-RGS1 antibody (ABIN453811) Images back to top
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

References for anti-RGS1 antibody (ABIN453811)

Product Details anti-RGS1 Antibody Target Details RGS1 Application Details Handling Images back to top
Background publications

Bowman, Campbell, Druey, Scheschonka, Kehrl, Butcher: "Regulation of chemotactic and proadhesive responses to chemoattractant receptors by RGS (regulator of G-protein signaling) family members." in: The Journal of biological chemistry, Vol. 273, Issue 43, pp. 28040-8, 1998

Images

Product Details anti-RGS1 Antibody Target Details RGS1 Application Details Handling References for anti-RGS1 antibody (ABIN453811) back to top
Supplier Images
Western Blotting (WB) image for anti-Regulator of G-Protein Signaling 1 (RGS1) (N-Term) antibody (ABIN453811) Western blot analysis of RGS1 Antibody (N-term) in HL-60 cell line lysates (35ug/lane...