Browse our anti-RPS6KA1 (RPS6KA1) Antibodies

Full name:
anti-Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 1 Antibodies (RPS6KA1)
On www.antibodies-online.com are 391 Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 1 (RPS6KA1) Antibodies from 28 different suppliers available. Additionally we are shipping RPS6KA1 Proteins (12) and RPS6KA1 Kits (10) and many more products for this protein. A total of 424 RPS6KA1 products are currently listed.
Synonyms:
CLS, hu-1, HU-3, ISPK-1, mapkapk1a, MAPKAPK1B, MRX19, p90-RSK2, p90rsk, pp90RSK2, RPS6KA, RSK, rsk1, RSK2, S6K-alpha3
list all antibodies Gene Name GeneID UniProt
RPS6KA1 20111  
RPS6KA1 81771 Q63531
RPS6KA1 6195 Q15418

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Most Popular Reactivities for anti-RPS6KA1 (RPS6KA1) Antibodies

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anti-Mouse (Murine) RPS6KA1 Antibodies:

anti-Rat (Rattus) RPS6KA1 Antibodies:

anti-Human RPS6KA1 Antibodies:

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Top referenced anti-RPS6KA1 Antibodies

  1. Chicken Monoclonal RPS6KA1 Primary Antibody for IF, IP - ABIN967837 : Chung, Pelech, Blenis: Mitogen-activated Swiss mouse 3T3 RSK kinases I and II are related to pp44mpk from sea star oocytes and participate in the regulation of pp90rsk activity. in Proceedings of the National Academy of Sciences of the United States of America 1991 (PubMed)
    Show all 5 references for 967837

  2. Human Polyclonal RPS6KA1 Primary Antibody for EIA - ABIN358393 : Roux, Ballif, Anjum, Gygi, Blenis: Tumor-promoting phorbol esters and activated Ras inactivate the tuberous sclerosis tumor suppressor complex via p90 ribosomal S6 kinase. in Proceedings of the National Academy of Sciences of the United States of America 2004 (PubMed)
    Show all 5 references for 358393

  3. Human Polyclonal RPS6KA1 Primary Antibody for DB, WB - ABIN1881765 : Bohuslav, Chen, Kwon, Mu, Greene: p53 induces NF-kappaB activation by an IkappaB kinase-independent mechanism involving phosphorylation of p65 by ribosomal S6 kinase 1. in The Journal of biological chemistry 2004 (PubMed)
    Show all 5 references for 1881765

  4. Cow (Bovine) Polyclonal RPS6KA1 Primary Antibody for ELISA, ICC - ABIN361702 : De Cesare, Jacquot, Hanauer, Sassone-Corsi: Rsk-2 activity is necessary for epidermal growth factor-induced phosphorylation of CREB protein and transcription of c-fos gene. in Proceedings of the National Academy of Sciences of the United States of America 1998 (PubMed)
    Show all 4 references for 361702

  5. Human Polyclonal RPS6KA1 Primary Antibody for WB - ABIN197330 : Silverman, Frödin, Gammeltoft, Maller: Activation of p90 Rsk1 is sufficient for differentiation of PC12 cells. in Molecular and cellular biology 2004 (PubMed)
    Show all 3 references for 197330

  6. Human Polyclonal RPS6KA1 Primary Antibody for IF, IHC (p) - ABIN196796 : Wingate, Campbell, Peggie, Arthur: Nur77 is phosphorylated in cells by RSK in response to mitogenic stimulation. in The Biochemical journal 2006 (PubMed)
    Show all 3 references for 196796

  7. Human Polyclonal RPS6KA1 Primary Antibody for IF, WB - ABIN197328 : Itoh, Ding, Bains, Wang, Takeishi, Jalili, King, Walsh, Yan, Abe: Role of p90 ribosomal S6 kinase (p90RSK) in reactive oxygen species and protein kinase C beta (PKC-beta)-mediated cardiac troponin I phosphorylation. in The Journal of biological chemistry 2005 (PubMed)
    Show all 3 references for 197328

  8. Human Polyclonal RPS6KA1 Primary Antibody for ELISA, WB - ABIN1043905 : Chaturvedi, Poppleton, Stringfield, Barbier, Patel: Subcellular localization and biological actions of activated RSK1 are determined by its interactions with subunits of cyclic AMP-dependent protein kinase. in Molecular and cellular biology 2006 (PubMed)

  9. Human Polyclonal RPS6KA1 Primary Antibody for EIA, IHC (p) - ABIN954622 : Gao, Chaturvedi, Patel: p90 ribosomal S6 kinase 1 (RSK1) and the catalytic subunit of protein kinase A (PKA) compete for binding the pseudosubstrate region of PKAR1alpha: role in the regulation of PKA and RSK1 activities. in The Journal of biological chemistry 2010 (PubMed)

More Antibodies against RPS6KA1 Interaction Partners

Mouse (Murine) Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 1 (RPS6KA1) interaction partners

  1. In hippocampal neurons of wild-type mice, pP90RSK translocates into the nucleus upon stimulation with forskolin (left), whereas in Period1-knockout (Per1 (show PER1 Antibodies)(-/-) ) mice (right) the kinase is trapped at the nuclear periphery

  2. Data show that the phosphoinositide-dependent kinase 1 (PDK1 (show PDPK1 Antibodies))-p90 (show GPAM Antibodies) kDa ribosomal S6 kinases (Rsks) Rsk1/2 pathway is critical for establishment and maintenance of a normal Langerhans cells (LC) network.

  3. IL-6 (show IL6 Antibodies) induces the activation of the Stat3 (show STAT3 Antibodies) signaling and promotes the downmodulation of the p90RSK/eEF2 (show EEF2 Antibodies) and mTOR (show FRAP1 Antibodies)/p70S6K (show RPS6KB1 Antibodies) axes, while it does not affect the activation of AKT (show AKT1 Antibodies).

  4. analysis of p38 (show CRK Antibodies)-MK2 (show KCNA2 Antibodies)-activated Rsk signaling in toll (show TLR4 Antibodies)-like receptor-stimulated dendritic cells

  5. These data indicate that aripiprazole and quetiapine signal to specific nuclear targets of ERK (show EPHB2 Antibodies), which for quetiapine occurs via an EGFR (show EGFR Antibodies)-linked mechanism, possibly indicating involvement of this system in its action.

  6. hypoxia/reoxygenation (H/R)-mediated decrease in PKARIalpha protein levels leads to activation of RSK1, which via phosphorylation of NHE1 (show SLC9A1 Antibodies) induces cardiomyocyte apoptosis.

  7. RSK1 Cys223 glutathionylation may contribute to regulate the levels of nitric in the brain.

  8. Our study highlights the importance of the p90RSK/ERK5 (show MAPK7 Antibodies) module as a critical mediator of endothelial dysfunction in diabetes mellitus and atherosclerosis formation.

  9. Results show increased protein levels of Rsk1 and Rsk2 (show RPS6KA3 Antibodies) in the striatum of Huntington disease (show HTT Antibodies) mice and and striatal cells transfected with full-length mutant Huntingtin (show HTT Antibodies).

  10. Type I keratin (show KRT12 Antibodies) 17 (show KRT17 Antibodies) protein is phosphorylated on serine 44 by p90 (show GPAM Antibodies) ribosomal protein S6 kinase 1 (RSK1) in a growth- and stress-dependent fashion

Human Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 1 (RPS6KA1) interaction partners

  1. Inhibition of RSK2 (show RPS6KA3 Antibodies) was used to investigate the function of RSK2 (show RPS6KA3 Antibodies) on PDK1 (show PDK1 Antibodies)-induced inflammation. The phosphorylation of RSK2 (show RPS6KA3 Antibodies) was detected when PDK1 (show PDK1 Antibodies) was inhibited. Inhibition of RSK2 (show RPS6KA3 Antibodies) reduced the PDK1 (show PDK1 Antibodies)-induced cell invasion and cytokines secretion in human rheumatoid arthritis synovial MH7A cells. In response to TNF-alpha (show TNF Antibodies), PDK1 (show PDK1 Antibodies) could phosphorylate RSK2 (show RPS6KA3 Antibodies) and activated RSK2 (show RPS6KA3 Antibodies), then promoting the activation of NF-kappaB (show NFKB1 Antibodies).

  2. Our finding demonstrates that RSK2 (show RPS6KA3 Antibodies) directly phosphorylates stathmin (show STMN1 Antibodies) and regulates microtubule polymerization to provide a pro-invasive and pro-metastatic advantage to cancer cells. Therefore, the RSK2 (show RPS6KA3 Antibodies)-stathmin (show STMN1 Antibodies) pathway represents a promising therapeutic target and a prognostic marker for metastatic human cancers.

  3. Data suggest that UBR5 (show UBR5 Antibodies) down-regulates levels of TRAF3 (show TRAF3 Antibodies), a key component of Toll (show TLR4 Antibodies)-like receptor signaling, via the miRNA pathway; p90RSK is an upstream regulator of UBR5 (show UBR5 Antibodies); p90RSK phosphorylates UBR5 (show UBR5 Antibodies) as required for translational repression of TRAF3 (show TRAF3 Antibodies) mRNA. (UBR5 (show UBR5 Antibodies) = ubiquitin protein ligase E3 component n-recognin 5 (show UBR5 Antibodies) protein; TRAF3 (show TRAF3 Antibodies) = TNF receptor-associated factor 3 (show TRAF3 Antibodies); p90RSK = 90 kDa ribosomal protein S6 (show RPS6 Antibodies) kinase (show RPS6KB1 Antibodies))

  4. Data indicate that BTG2 (show BTG2 Antibodies), MAP3K11 (show MAP3K11 Antibodies), RPS6KA1 and PRDM1 (show PRDM1 Antibodies) as putative targets of microRNA miR (show MLXIP Antibodies)-125b.

  5. VEGF-A (show VEGFA Antibodies) driven Mdm2 (show MDM2 Antibodies) phosphorylation on Ser166 is dependent on the ERK1/2 (show MAPK1/3 Antibodies)/p90RSK signaling pathway in primary human endothelial cells.

  6. we discuss the function of the RSK2 (show RPS6KA3 Antibodies) signaling axis by interactions with binding partners in cancer development--{REVIEW}

  7. Results showed that RSK2 (show RPS6KA3 Antibodies) gene was overexpressed in osteosarcoma patients cells and its knockdown increased cell apoptosis, enhanced cell chemosensitivity, inhibits proliferation and migration, and weakened tumor formation.

  8. Upregulated expression of RSK2 (show RPS6KA3 Antibodies) is associated with breast cancer.

  9. The p90RSK has an essential role in promoting tumor growth and proliferation in non-small cell lung cancer (NSCLC). BID (show BID Antibodies) may serve as an alternative cancer treatment in NSCLC.

  10. RSK1 binds to EBP50 (show SLC9A3R1 Antibodies) at its first PDZ domain (show INADL Antibodies), and mitogen activated RSK1 phosphorylates EBP50 (show SLC9A3R1 Antibodies) at T156, an event that is crucial for its nuclear localization

RPS6KA1 Antigen Profile

Antigen Summary

This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Mutations in this gene have been associated with Coffin-Lowry syndrome (CLS).

Alternative names and synonyms associated with RPS6KA1

  • ribosomal protein S6 kinase polypeptide 1 (Rps6ka1) antibody
  • ribosomal protein S6 kinase, 90kDa, polypeptide 1 (RPS6KA1) antibody
  • ribosomal protein S6 kinase, 90kDa, polypeptide 1 (rps6ka1) antibody
  • ribosomal protein S6 kinase, 90kDa, polypeptide 3 (RPS6KA3) antibody
  • CLS antibody
  • hu-1 antibody
  • HU-3 antibody
  • ISPK-1 antibody
  • mapkapk1a antibody
  • MAPKAPK1B antibody
  • MRX19 antibody
  • p90-RSK2 antibody
  • p90rsk antibody
  • pp90RSK2 antibody
  • RPS6KA antibody
  • RSK antibody
  • rsk1 antibody
  • RSK2 antibody
  • S6K-alpha3 antibody

Protein level used designations for RPS6KA1

90 kDa ribosomal protein S6 kinase 1 , MAP kinase-activated protein kinase 1a , MAPK-activated protein kinase 1a , MAPKAP kinase 1a , MAPKAPK-1a , RSK-1 , S6K-alpha-1 , p90-RSK 1 , p90RSK1 , p90S6K , ribosomal S6 kinase 1 , ribosomal protein S6 kinase alpha-1 , ribosomal protein S6 kinase, 90kD, polypeptide 1; Ribosomal protein S6 kinase, 90kD, 1 , MAPKAPK1A , S6 protein kinase (Rsk-1) , S6K-alpha 1 , pp90RSK1 , dJ590P13.1 (ribosomal protein S6 kinase, 90kD, polypeptide 1) , ribosomal protein S6 kinase alpha 1 , MAP kinase-activated protein kinase 1 , MAPK-activated protein kinase 1 , MAPKAP kinase 1 , MAPKAPK-1 , S6KII-alpha , p90-RSK , ribosomal protein S6 kinase 2 alpha , ribosomal protein S6 kinase II alpha , P90-RSK , S6 kinase II beta , S6KII-beta , ribosomal protein S6 kinase 2 beta , ribosomal protein S6 kinase II beta , MAP kinase-activated protein kinase 1b , MAPK-activated protein kinase 1b , MAPKAP kinase 1b , MAPKAPK-1b , RSK-2 , S6K-alpha-3 , insulin-stimulated protein kinase 1 , p90-RSK 3 , ribosomal S6 kinase 2 , ribosomal protein S6 kinase alpha-3

GENE ID SPECIES
20111 Mus musculus
81771 Rattus norvegicus
533908 Bos taurus
6195 Homo sapiens
386579 Gallus gallus
487353 Canis lupus familiaris
100057166 Equus caballus
100523972 Sus scrofa
445821 Xenopus laevis
6197 Homo sapiens
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