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anti-Opossum (Didelphimorphia) RPS6KA1 antibody for Enzyme Immunoassay

Recommended RPS6KA1 Antibody (supplied by: Log in to see )

Antigen
Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 1 (RPS6KA1) Antibodies
  • CLS
  • hu-1
  • HU-1
  • HU-3
  • ISPK-1
  • mapkapk1a
  • MAPKAPK1A
  • MAPKAPK1B
  • MRX19
  • p90-RSK2
  • p90rsk
  • pp90RSK2
  • RPS6KA
  • rsk
  • RSK
  • RSK1
  • rsk1
  • Rsk1
  • RSK2
  • S6K-alpha3
Epitope
C-Term, pSer732
65
40
32
24
22
18
15
12
10
9
9
8
7
6
5
4
3
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Cow (Bovine), Dog (Canine), Chicken, Horse (Equine), Human, Mouse (Murine), Opossum (Didelphimorphia), Rat (Rattus)
313
142
113
27
10
5
5
2
2
Host
Rabbit
311
39
Clonality
Polyclonal
Conjugate
This RPS6KA1 antibody is un-conjugated
20
19
17
12
12
12
5
5
5
5
5
5
5
5
4
1
1
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
245
157
96
54
51
39
34
20
10
6
2
1
1
Supplier
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Catalog No. ABIN401473
$ 500.50
Plus shipping costs $45.00

Top referenced anti-RPS6KA1 antibody for Enzyme Immunoassay

Similar anti-RPS6KA1 Antibodies

Application / Reactivity Cow (Bovine) Human Mouse (Murine) Rat (Rattus) Dog (Canine) Chicken Horse (Equine) Opossum (Didelphimorphia)
Western Blotting (WB) 28 Antibodies 223 Antibodies 102 Antibodies 76 Antibodies 10 Antibodies 5 Antibodies 6 Antibodies 1 Antibodies
Immunoprecipitation (IP) 20 Antibodies 39 Antibodies 24 Antibodies 25 Antibodies 2 Antibodies 2 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 1 Antibodies 49 Antibodies 21 Antibodies 21 Antibodies
Immunohistochemistry (IHC) 1 Antibodies

General

Antigen Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 1 (RPS6KA1) Antibodies
Epitope C-Term, pSer732
(65), (40), (32), (24), (22), (18), (15), (12), (10), (9), (9), (8), (7), (6), (5), (4), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Cow (Bovine), Dog (Canine), Chicken, Horse (Equine), Human, Mouse (Murine), Opossum (Didelphimorphia), Rat (Rattus)
(313), (142), (113), (27), (10), (5), (5), (2), (2)
Host Rabbit
(311), (39)
Clonality
Polyclonal
Conjugate This RPS6KA1 antibody is un-conjugated
(20), (19), (17), (12), (12), (12), (5), (5), (5), (5), (5), (5), (5), (5), (4), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Enzyme Immunoassay (EIA), Western Blotting (WB)
(245), (157), (96), (54), (51), (39), (34), (20), (10), (6), (2), (1), (1)
Pubmed 1 reference available
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Product Details anti-RPS6KA1 Antibody

Target Details RPS6KA1 Application Details Handling References for anti-RPS6KA1 Antibody (ABIN401473) Images
Specificity This antibody is specific for p90 RSK1 protein phosphorylated at S732.
Cross-Reactivity (Details) Species reactivity (expected):Rat, Mouse, Horse, Bovine, Canine, Opossum, Chicken.
Species reactivity (tested):Human.
Purification Affinity chromatography
Immunogen Synthetic peptide corresponding to a region near the C-terminal end of human RSK1 protein
Isotype IgG

Target Details RPS6KA1

Product Details anti-RPS6KA1 Antibody Application Details Handling References for anti-RPS6KA1 Antibody (ABIN401473) Images back to top
Antigen
Alternative Name RPS6KA1 (RPS6KA1 Antibody Abstract)
Background Ribosomal S6 Kinase 1 (RSK1, S6K-alpha 1, 90 kDa Ribosomal Protein S6 Kinase 1, MAP kinase-activated protein kinase 1a, or MAPKAPK1A) is an immediate downstream effector of mitogen activated protein kinases and therefore promotes cell proliferation and survival. It has serine/threonine kinase activity and may play a role in mediating the growth-factor and stress-induced activation of the transcription factor CREB. The C-terminal region of RSK1 is reported to be an ERK docking site, where serine 732 phosphorylation status is critical for RSK1 activation. When serine 732 is not phosphorylated, ERK1/2 binds to the ERK docking site of RSK1, and upon stimulation, activates RSK1. The activated RSK1 then autophosphorylates serine 732, leading to the dissociation of ERK from RSK1 and termination of activation by ERK.Synonyms: 90 kDa ribosomal protein S6 kinase 1, MAPKAPK1A, RSK-1, RSK1, Ribosomal S6 kinase 1, Ribosomal protein S6 kinase alpha-1, p90RSK1
Gene ID 6195
NCBI Accession NP_001006666
UniProt Q15418
Research Area Signaling
Pathways MAPK Signaling, Neurotrophin Signaling Pathway

Application Details

Product Details anti-RPS6KA1 Antibody Target Details RPS6KA1 Handling References for anti-RPS6KA1 Antibody (ABIN401473) Images back to top
Application Notes ELISA: 1/100,000. Western Blot: 1/500 - 1/2,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-RPS6KA1 Antibody Target Details RPS6KA1 Application Details References for anti-RPS6KA1 Antibody (ABIN401473) Images back to top
Format Liquid
Concentration 0.64 mg/mL (by UV absorbance at 280 nm)
Buffer 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage -20 °C

References for anti-RPS6KA1 Antibody (ABIN401473)

Product Details anti-RPS6KA1 Antibody Target Details RPS6KA1 Application Details Handling Images back to top
Background publications

Chaturvedi, Poppleton, Stringfield, Barbier, Patel: "Subcellular localization and biological actions of activated RSK1 are determined by its interactions with subunits of cyclic AMP-dependent protein kinase." in: Molecular and cellular biology, Vol. 26, Issue 12, pp. 4586-600, 2006

Images

Product Details anti-RPS6KA1 Antibody Target Details RPS6KA1 Application Details Handling References for anti-RPS6KA1 Antibody (ABIN401473) back to top
Supplier Images
 image for anti-RPS6KA1 antibody (Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 1) (C-Term) (ABIN401473) anti-Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 1 (RPS6KA1) (C-Term), (pSer732) antibody