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Browse our anti-RPS6KA5 (RPS6KA5) Antibodies

Full name:
anti-Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 5 Antibodies (RPS6KA5)
On are 213 Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 5 (RPS6KA5) Antibodies from 25 different suppliers available. Additionally we are shipping RPS6KA5 Kits (10) and RPS6KA5 Proteins (8) and many more products for this protein. A total of 251 RPS6KA5 products are currently listed.
3110005L17Rik, 6330404E13Rik, AI854034, Msk1, MSPK1, RLPK
list all antibodies Gene Name GeneID UniProt
RPS6KA5 9252 O75582
RPS6KA5 73086 Q8C050
RPS6KA5 314384  

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anti-Human RPS6KA5 Antibodies:

anti-Mouse (Murine) RPS6KA5 Antibodies:

anti-Rat (Rattus) RPS6KA5 Antibodies:

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Top referenced anti-RPS6KA5 Antibodies

  1. Human Polyclonal RPS6KA5 Primary Antibody for WB - ABIN362838 : Roux, Blenis: ERK and p38 MAPK-activated protein kinases: a family of protein kinases with diverse biological functions. in Microbiology and molecular biology reviews : MMBR 2004 (PubMed)
    Show all 2 references for ABIN362838

  2. Human Polyclonal RPS6KA5 Primary Antibody for WB - ABIN197422 : McCoy, Campbell, Deak, Bloomberg, Arthur: MSK1 activity is controlled by multiple phosphorylation sites. in The Biochemical journal 2005 (PubMed)
    Show all 2 references for ABIN197422

More Antibodies against RPS6KA5 Interaction Partners

Human Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 5 (RPS6KA5) interaction partners

  1. Interrupting MSK1 activation is a new target for antioxidants.

  2. Increased MSK1 activity is critically important for Epstein-Barr virus LMP1 (show PDLIM7 Antibodies)-promoted cell proliferation and transformation.

  3. KSHV activates the MSK1/2-CREB1 (show CREB1 Antibodies) pathway during primary infection and that it depends on this pathway for viral lytic replication. I

  4. Authors conclude that paramyxoviruses trigger the DNA damage response, a pathway required for MSK1 activation of phospho Ser (show SIGLEC1 Antibodies) 276 RelA (show NFkBP65 Antibodies) formation to trigger the IRF7 (show IRF7 Antibodies)-RIG-I (show DDX58 Antibodies) amplification loop necessary for mucosal interferon (show IFNA Antibodies) production.

  5. These results highlight the relevance of MSK1 in the up-regulation of RARbeta (show RARB Antibodies) by prostaglandin E2.

  6. Data suggest that MSK1 and MSK2 are the major CREB (show CREB1 Antibodies) kinases in fibroblast-like synoviocytes from rheumatoid arthritis patients stimulated with lysophosphatidic acid and that phosphorylation of CREB1 (show CREB1 Antibodies) at Ser (show SIGLEC1 Antibodies)-133 plays a significant role in IL-8 (show IL8 Antibodies) production.

  7. MSK1 plays an important role for hormone-dependent breast cancer growth

  8. MSK1 and MSK2 are required for maximal TFF 1 (show TFF1 Antibodies) induction.

  9. Angiopoietin 2 (show ANGPT2 Antibodies)-mediated signaling via survivin (show BIRC5 Antibodies)/ref-1 (show APEX1 Antibodies)/MSK-1 pathway promotes doxorubicin resistance in HepG2 cells.

  10. Astaxanthin attenuates the UVB-induced secretion of prostaglandin E2 and interleukin-8 (show IL8 Antibodies) in human keratinocytes by interrupting MSK1 phosphorylation in a ROS (show ROS1 Antibodies) depletion-independent manner

Cow (Bovine) Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 5 (RPS6KA5) interaction partners

  1. essential role of the C-terminal domain of MSK1 for its constitutive interaction with group V secretory phospholipase A (show HRASLS Antibodies)(2), which appears essential to support VEGF (show VEGFA Antibodies)-mediated PAF (show KIAA0101 Antibodies) synthesis

Mouse (Murine) Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 5 (RPS6KA5) interaction partners

  1. Accelerated apoptotic death and in vivo turnover of erythrocytes have been found in mice lacking functional MSK1/MSK2.

  2. Results suggest that MSK1/2 plays a significant role in the regulation of ischemia-induced progenitor cell proliferation and neurogenesis

  3. MSK1 has a role in malignant transformation and skin cancer development, but is inhibited by chrysin derivative 69407

  4. the impact of MSK1 on glucocorticoid receptor (show NR3C1 Antibodies)-mediated transactivation

  5. MSK1 is an important novel molecule involved in RANKL (show TNFSF11 Antibodies) signaling and osteoclast differentiation

  6. MSK1/2 knockout results in reduced IL-10 (show IL10 Antibodies) secretion.

  7. MSK1-deficient mice exhibit a decreased capacity to entrain to a new light cycle, attenuated Period1 expression, histone phosporylation and CREB (show CREB1 Antibodies) phosphorylation.

  8. these data reveal that MSK1 serves as a critical regulator of hippocampal physiology and function

  9. data reveal a critical role for MSK1/2 as regulators of both basal and activity-dependent progenitor cell proliferation and morphological maturation in the subgranular zone

  10. This study demonstrated that MSK1 is an integral part of a signaling pathway that underlies the adaptive response to synaptic and environmental experience.

RPS6KA5 Antigen Profile

Antigen Summary

Serine/threonine-protein kinase that is required for the mitogen or stress-induced phosphorylation of the transcription factors CREB1 and ATF1 and for the regulation of the transcription factors RELA, STAT3 and ETV1/ER81, and that contributes to gene activation by histone phosphorylation and functions in the regulation of inflammatory genes. Phosphorylates CREB1 and ATF1 in response to mitogenic or stress stimuli such as UV-C irradiation, epidermal growth factor (EGF) and anisomycin. Plays an essential role in the control of RELA transcriptional activity in response to TNF and upon glucocorticoid, associates in the cytoplasm with the glucocorticoid receptor NR3C1 and contributes to RELA inhibition and repression of inflammatory gene expression. In skeletal myoblasts is required for phosphorylation of RELA at 'Ser-276' during oxidative stress. In erythropoietin-stimulated cells, is necessary for the 'Ser-727' phosphorylation of STAT3 and regulation of its transcriptional potential. Phosphorylates ETV1/ER81 at 'Ser-191' and 'Ser-216', and thereby regulates its ability to stimulate transcription, which may be important during development and breast tumor formation. Directly represses transcription via phosphorylation of 'Ser-1' of histone H2A. Phosphorylates 'Ser-10' of histone H3 in response to mitogenics, stress stimuli and EGF, which results in the transcriptional activation of several immediate early genes, including proto- oncogenes c-fos/FOS and c-jun/JUN. May also phosphorylate 'Ser-28' of histone H3. Mediates the mitogen- and stress-induced phosphorylation of high mobility group protein 1 (HMGN1/HMG14). In lipopolysaccharide-stimulated primary macrophages, acts downstream of the Toll-like receptor TLR4 to limit the production of pro- inflammatory cytokines. Functions probably by inducing transcription of the MAP kinase phosphatase DUSP1 and the anti- inflammatory cytokine interleukin 10 (IL10), via CREB1 and ATF1 transcription factors. Plays a role in neuronal cell death by mediating the downstream effects of excitotoxic injury.

Alternative names and synonyms associated with RPS6KA5

  • ribosomal protein S6 kinase, 90kDa, polypeptide 5 (RPS6KA5) antibody
  • ribosomal protein S6 kinase, polypeptide 5 (Rps6ka5) antibody
  • 3110005L17Rik antibody
  • 6330404E13Rik antibody
  • AI854034 antibody
  • Msk1 antibody
  • MSPK1 antibody
  • RLPK antibody

Protein level used designations for RPS6KA5

90 kDa ribosomal protein S6 kinase 5 , RSK-like protein kinase , RSKL , S6K-alpha-5 , nuclear mitogen- and stress-activated protein kinase 1 , ribosomal protein S6 kinase alpha-5 , mitogen- and stress-activated protein kinase-1 , ribosomal protein S6 kinase, polypeptide 5 , RLSK , mitogen and stress-activated protein kinase 1 , ribosomal protein S6 kinase, 90kDa, polypeptide 5

9252 Homo sapiens
504408 Bos taurus
423408 Gallus gallus
73086 Mus musculus
314384 Rattus norvegicus
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