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Browse our SGK1 Proteins (SGK1)

Full name:
serum/glucocorticoid Regulated Kinase 1 Proteins (SGK1)
On www.antibodies-online.com are 19 serum/glucocorticoid Regulated Kinase 1 (SGK1) Proteins from 8 different suppliers available. Additionally we are shipping SGK1 Antibodies (216) and SGK1 Kits (12) and many more products for this protein. A total of 264 SGK1 products are currently listed.
Synonyms:
cb1083, sgk, wu:fc20a09
list all proteins Gene Name GeneID UniProt
SGK1 6446 O00141
SGK1 20393 Q9WVC6
SGK1 29517  

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SGK1 Proteins (SGK1) by Origin

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Top referenced SGK1 Proteins

  1. Human SGK1 Protein expressed in Escherichia coli (E. coli) - ABIN667573 : Maiyar, Huang, Phu, Cha, Firestone: p53 stimulates promoter activity of the sgk. serum/glucocorticoid-inducible serine/threonine protein kinase gene in rodent mammary epithelial cells. in The Journal of biological chemistry 1996 (PubMed)
    Show all 2 references for ABIN667573

More Proteins for SGK1 Interaction Partners

Human serum/glucocorticoid Regulated Kinase 1 (SGK1) interaction partners

  1. data suggest that the induction of SGK1 through treatment with dexamethasone alters MT dynamics to increase Sec5-GEF-H1 (show ARHGEF2 Proteins) interactions, which promote GEF-H1 (show ARHGEF2 Proteins) targeting to adhesion sites.

  2. This review focuses on recent advances in understanding of the roles of Akt (show AKT1 Proteins) and SGK1 in the regulation of renal tubular transport.

  3. SGK1 is overexpressed in non-small cell lung cancer.SGK1 positively regulates the growth, migration and metastasis of non-small cell lung cancer.SGK1 activates beta-catenin (show CTNNB1 Proteins) signaling in NSCLC cells.

  4. Data suggest that SGK1 expression is down-regulated in prefrontal cortex neurons of post-traumatic stress disorders subjects (male and female; postmortem samples obtained from tissue bank).

  5. SGK1 plays a pivotal role in vascular inflammation during atherogenesis. SGK1 participates in the regulation of monocyte/macrophage migration and MMP-9 (show MMP9 Proteins) transcription via regulation of nuclear factor-kappaB.

  6. SGK1 was up-regulated in CD4 (show CD4 Proteins) T cells

  7. SGK1 inhibits intestinal epithelial cell apoptosis and promotes proliferation via the MEK (show MAP2K1 Proteins)/ERK (show EPHB2 Proteins)/p53 (show TP53 Proteins) pathway in colitis.

  8. Increased SGK-1 expression reduces oxidative stress and improves cell survival in endothelial cells.

  9. These findings have identified an anti-inflammatory function of SGK1, elucidated the underlying intracellular mechanisms

  10. FE65 (show APBB1 Proteins) influences APP (show APP Proteins) degradation via the proteasome, and phosphorylation of FE65 (show APBB1 Proteins) Ser (show SIGLEC1 Proteins)(610) by SGK1 regulates binding of FE65 (show APBB1 Proteins) to APP (show APP Proteins), APP (show APP Proteins) turnover and processing.

Mouse (Murine) serum/glucocorticoid Regulated Kinase 1 (SGK1) interaction partners

  1. High salt diet may deteriorate lupus nephritis through SGK1 pathway.

  2. Study shows that SGK1 impairs nuclear abundance of p27 (show CDKN1B Proteins) and suggests that phosphorylation of p27T197 by SGK1 is required for cardiac hypertrophy.

  3. SGK1 appears to be an important enzyme in the process of fibrotic remodeling and subsequent weakness of dystrophin (show DMD Proteins)-deficient mouse muscle

  4. The characterisation of SGK1 functions in obesity and immunity may help identify potential therapeutic targets in the treatment of obesity.

  5. Identify SGK1 as a novel powerful regulator of platelet dense granule biogenesis, platelet secretion and thrombus formation. SGK1 is at least partially effective because it regulates transcription of Rab27b (show RAB27B Proteins) in megakaryocytes.

  6. SGK1 plays a pivotal role in vascular inflammation during atherogenesis. SGK1 participates in the regulation of monocyte/macrophage migration and MMP-9 (show MMP9 Proteins) transcription via regulation of nuclear factor-kappaB.

  7. SGK1 inhibits intestinal epithelial cell apoptosis and promotes proliferation via the MEK (show MDK Proteins)/ERK (show EPHB2 Proteins)/p53 (show TP53 Proteins) pathway in colitis.

  8. measured gene expression of Fos, Per1 and Sgk1 45 min after exposure to brief cold swim stress in male and female mice; Sgk1 was insensitive to handling, and increased in response to stress similarly in males and females

  9. 17beta-estradiol attenuates LPS (show TLR4 Proteins)-induced acute lung injury via PI3K/Akt (show AKT1 Proteins)/SGK1 mediated up-regulation of Scnn1a (show SCNN1A Proteins).

  10. These findings have identified an anti-inflammatory function of SGK1, elucidated the underlying intracellular mechanisms

SGK1 Protein Profile

Protein Summary

This gene encodes a serine/threonine protein kinase that plays an important role in cellular stress response. This kinase activates certain potassium, sodium, and chloride channels, suggesting an involvement in the regulation of processes such as cell survival, neuronal excitability, and renal sodium excretion. High levels of expression of this gene may contribute to conditions such as hypertension and diabetic nephropathy. Several alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

Alternative names and synonyms associated with SGK1

  • serum/glucocorticoid regulated kinase 1 (SGK1)
  • serum/glucocorticoid regulated kinase 1 (Sgk1)
  • serum/glucocorticoid regulated kinase 1 (sgk1)
  • cb1083 protein
  • sgk protein
  • wu:fc20a09 protein

Protein level used designations for SGK1

Sgk1 variant i3 , serine/threonine protein kinase SGK , serine/threonine-protein kinase Sgk1 , serum/glucocorticoid-regulated kinase 1 , serum and glucocorticoid-dependent protein kinase , serum/glucocorticoid regulatory kinase , serum- and glucocorticoid-induced kinase , serum and glucocorticoid-regulated protein kinase

GENE ID SPECIES
6446 Homo sapiens
20393 Mus musculus
29517 Rattus norvegicus
403647 Canis lupus familiaris
100625739 Sus scrofa
515854 Bos taurus
395133 Gallus gallus
100008723 Oryctolagus cuniculus
324140 Danio rerio
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