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anti-Human SIRT1 antibody for Immunofluorescence (Paraffin-embedded Sections)

Recommended SIRT1 Antibody (supplied by: Log in to see )

Antigen
Sirtuin 1 (SIRT1) Antibodies
  • sirtuin 1
  • AA673258
  • SIR2L1
  • Sir2
  • Sir2a
  • Sir2alpha
  • sir2l1
  • sirtuin
  • SIR2
  • sirtuin 1
  • SIRT1
  • SRT1
  • LOC100349271
  • Sirt1
  • sirt1
Epitope
AA 20-60, pSer47
30
22
20
17
17
17
16
13
12
10
5
4
3
3
3
3
3
3
3
3
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine)
280
124
64
21
9
8
6
4
3
3
2
2
2
2
1
1
Host
Rabbit
185
80
27
7
3
Clonality
Polyclonal
Conjugate
This SIRT1 antibody is un-conjugated
15
13
10
6
6
5
4
4
4
3
3
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
1
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
233
130
75
63
60
48
33
30
27
5
5
4
4
2
2
1
Options
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Catalog No. ABIN745658
$ 291.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN729853 IF (p) IHC (p) WB Rabbit IgG AA 192-242 Log in to see Polyclonal 1
1 ABIN746003 IF (p) IHC (p) WB Rabbit IgG AA 1-50, pSer27 Log in to see Polyclonal
1 ABIN679028 IF (p) IHC (p) WB Rabbit IgG Log in to see Polyclonal
1 ABIN745662 IF (p) Cy5 Rabbit IgG AA 20-60, pSer47 Log in to see Polyclonal
1 ABIN745661 IF (p) Cy3 Rabbit IgG AA 20-60, pSer47 Log in to see Polyclonal
1 ABIN745663 IF (p) Cy5.5 Rabbit IgG AA 20-60, pSer47 Log in to see Polyclonal
1 ABIN745664 IF (p) Cy7 Rabbit IgG AA 20-60, pSer47 Log in to see Polyclonal
1 ABIN745665 IF (p) FITC Rabbit IgG AA 20-60, pSer47 Log in to see Polyclonal
1 ABIN729859 IF (p) Cy7 Rabbit IgG AA 192-242 Log in to see Polyclonal
1 ABIN729856 IF (p) Cy3 Rabbit IgG AA 192-242 Log in to see Polyclonal
1 ABIN729857 IF (p) Cy5 Rabbit IgG AA 192-242 Log in to see Polyclonal
1 ABIN729860 IF (p) FITC Rabbit IgG AA 192-242 Log in to see Polyclonal
1 ABIN876309 IF (p) Alexa Fluor 350 Rabbit IgG AA 20-60, pSer47 Log in to see Polyclonal
1 ABIN876311 IF (p) Alexa Fluor 555 Rabbit IgG AA 20-60, pSer47 Log in to see Polyclonal
1 ABIN876312 IF (p) Alexa Fluor 647 Rabbit IgG AA 20-60, pSer47 Log in to see Polyclonal
1 ABIN876310 IF (p) Alexa Fluor 488 Rabbit IgG AA 20-60, pSer47 Log in to see Polyclonal
1 ABIN729858 IF (p) Cy5.5 Rabbit IgG AA 192-242 Log in to see Polyclonal
1 ABIN915277 IF (p) Alexa Fluor 488 Rabbit IgG AA 192-242 Log in to see Polyclonal
1 ABIN915278 IF (p) Alexa Fluor 647 Rabbit IgG AA 192-242 Log in to see Polyclonal
1 ABIN915276 IF (p) Alexa Fluor 555 Rabbit IgG AA 192-242 Log in to see Polyclonal

Top referenced anti-SIRT1 antibody for Immunofluorescence (Paraffin-embedded Sections)

Similar anti-SIRT1 Antibodies

Application / Reactivity Mouse (Murine) Human
ELISA 56 Antibodies 113 Antibodies
Enzyme Immunoassay (EIA) 2 Antibodies 4 Antibodies
Flow Cytometry (FACS) 17 Antibodies 30 Antibodies
Immunocytochemistry (ICC) 19 Antibodies 45 Antibodies
Immunofluorescence (IF) 25 Antibodies 62 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 33 Antibodies
Immunohistochemistry (IHC) 31 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 2 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 29 Antibodies
Immunoprecipitation (IP) 2 Antibodies
Simple Western (SimWes) 2 Antibodies
Western Blotting (WB) 84 Antibodies
Chromatin Immunoprecipitation (ChIP) 5 Antibodies
ELISA (Capture) 1 Antibodies
Immunochromatography (IC) 2 Antibodies

General

Antigen Sirtuin 1 (SIRT1) Antibodies
Epitope AA 20-60, pSer47
(30), (22), (20), (17), (17), (17), (16), (13), (12), (10), (5), (4), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine)
(280), (124), (64), (21), (9), (8), (6), (4), (3), (3), (2), (2), (2), (2), (1), (1)
Host Rabbit
(185), (80), (27), (7), (3)
Clonality
Polyclonal
Conjugate This SIRT1 antibody is un-conjugated
(15), (13), (10), (6), (6), (5), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (1)
Application Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(233), (130), (75), (63), (60), (48), (33), (30), (27), (5), (5), (4), (4), (2), (2), (1)
Pubmed 2 references available
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Product Details anti-SIRT1 Antibody

Target Details SIRT1 Application Details Handling References for anti-SIRT1 Antibody (ABIN745658) Images
Purification Purified by Protein A.
Immunogen KLH conjugated synthetic phosphopeptide derived from human SirT1 around the phosphorylation site of Ser47
Isotype IgG

Target Details SIRT1

Product Details anti-SIRT1 Antibody Application Details Handling References for anti-SIRT1 Antibody (ABIN745658) Images back to top
Antigen
Alternative Name Sirt1 (SIRT1 Antibody Abstract)
Background

This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined,however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Alternative splicing results in multiple transcript variants.

Subcellular location: Cytoplasm, Nucleus


Synonyms: SIR2L1,NAD-dependent protein deacetylase sirtuin-1,hSIRT1,Regulatory protein SIR2 homolog 1,SIR2-like protein 1,hSIR2,SIRT1
Gene ID 23411
UniProt Q96EB6
Research Area Chromatin and Nuclear Signaling, Apoptosis/Necrosis, Proteases
Pathways MAPK Signaling

Application Details

Product Details anti-SIRT1 Antibody Target Details SIRT1 Handling References for anti-SIRT1 Antibody (ABIN745658) Images back to top
Application Notes WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
Restrictions For Research Use only

Handling

Product Details anti-SIRT1 Antibody Target Details SIRT1 Application Details References for anti-SIRT1 Antibody (ABIN745658) Images back to top
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C
Expiry Date 12 months

References for anti-SIRT1 Antibody (ABIN745658)

Product Details anti-SIRT1 Antibody Target Details SIRT1 Application Details Handling Images back to top
Product cited in:

Suzuki, Bandoski, Bartlett: "Fluoride induces oxidative damage and SIRT1/autophagy through ROS-mediated JNK signaling." in: Free radical biology & medicine, Vol. 89, pp. 369-378, 2015

Suzuki, Bartlett: "Sirtuin1 and autophagy protect cells from fluoride-induced cell stress." in: Biochimica et biophysica acta, Vol. 1842, Issue 2, pp. 245-55, 2014

Images

Product Details anti-SIRT1 Antibody Target Details SIRT1 Application Details Handling References for anti-SIRT1 Antibody (ABIN745658) back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-SIRT1 antibody (Sirtuin 1) (AA 20-60) (ABIN745658) Formalin-fixed and paraffin embedded rat brain labeled with Anti-Phospho-SIRT1(Ser47)...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-SIRT1 antibody (Sirtuin 1) (AA 20-60) (ABIN745658) Formalin-fixed and paraffin embedded human lung carcinoma labeled with Rabbit Anti-SI...