anti-Rat (Rattus) SIRT1 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended SIRT1 Antibody (supplied by: Log in to see )

Antigen
Sirtuin 1 (SIRT1) Antibodies
  • sirtuin 1
  • AA673258
  • SIR2L1
  • Sir2
  • Sir2a
  • Sir2alpha
  • sir2l1
  • sirtuin
  • SIR2
  • sirtuin 1
  • SIRT1
  • SRT1
  • LOC100349271
  • Sirt1
  • sirt1
Epitope
AA 192-242
29
24
21
18
16
15
14
14
10
6
6
5
4
3
3
3
3
3
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
306
137
70
21
14
11
8
7
7
7
5
4
4
3
2
2
2
1
Host
Rabbit
206
86
27
6
3
Clonality
Polyclonal
Conjugate
This SIRT1 antibody is un-conjugated
17
14
10
7
7
6
4
4
4
4
4
4
4
4
4
3
3
3
3
3
3
3
3
2
2
2
2
2
1
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
255
132
87
66
60
51
42
39
36
7
6
5
4
2
2
2
2
1
1
Options
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Catalog No. ABIN729853
$ 307.45
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
13.4040785 ABIN4353901 ELISA FACS ICC IF IHC IHC (p) WB Mouse IgG1 Log in to see 1F3 1
1 ABIN214144 IHC (p) WB Rabbit IgG AA 207-256 Log in to see Polyclonal
1 ABIN729862 IHC (p) WB HRP Rabbit IgG AA 192-242 Log in to see Polyclonal
1 ABIN729855 IHC (p) WB Biotin Rabbit IgG AA 192-242 Log in to see Polyclonal
1 ABIN4353900 ELISA FACS ICC IF IHC IHC (p) WB Mouse IgG1 Log in to see 1F3
1 ABIN4963887 ELISA FACS ICC IF IHC IHC (p) WB DyLight 755 Mouse IgG1 Log in to see 1F3
1 ABIN4963877 ELISA FACS ICC IF IHC IHC (p) WB Alexa Fluor 488 Mouse IgG1 Log in to see 1F3
1 ABIN4963882 ELISA FACS ICC IF IHC IHC (p) WB DyLight 650 Mouse IgG1 Log in to see 1F3
1 ABIN4963885 ELISA FACS ICC IF IHC IHC (p) WB DyLight 488 Mouse IgG1 Log in to see 1F3
1 ABIN4963888 ELISA FACS ICC IF IHC (p) WB PerCP Mouse IgG1 Log in to see 1F3
1 ABIN4963891 ELISA FACS ICC IF IHC IHC (p) WB DyLight 350 Mouse IgG1 Log in to see 1F3
1 ABIN4963881 ELISA ICC IF IHC IHC (p) WB Biotin Mouse IgG1 Log in to see 1F3
1 ABIN4963892 ELISA FACS ICC IF IHC IHC (p) WB DyLight 405 Mouse IgG1 Log in to see 1F3
1 ABIN4963879 ELISA FACS ICC IF IHC IHC (p) WB Alexa Fluor 700 Mouse IgG1 Log in to see 1F3
1 ABIN4963884 ELISA FACS ICC IF IHC IHC (p) WB DyLight 680 Mouse IgG1 Log in to see 1F3
1 ABIN4963890 ELISA FACS ICC IF IHC IHC (p) WB DyLight 550 Mouse IgG1 Log in to see 1F3
1 ABIN4963876 ELISA FACS ICC IF IHC IHC (p) WB Alexa Fluor 405 Mouse IgG1 Log in to see 1F3
1 ABIN4963883 ELISA FACS ICC IF IHC IHC (p) FITC Mouse IgG1 Log in to see 1F3
1 ABIN4963878 ELISA FACS ICC IF IHC IHC (p) WB Alexa Fluor 647 Mouse IgG1 Log in to see 1F3
1 ABIN4963886 ELISA IHC IHC (p) WB HRP Mouse IgG1 Log in to see 1F3

Top referenced anti-SIRT1 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Similar anti-SIRT1 Antibodies

Application / Reactivity Rat (Rattus) Mouse (Murine)
Chromatin Immunoprecipitation (ChIP) 3 Antibodies
ELISA 35 Antibodies 58 Antibodies
Enzyme Immunoassay (EIA) 1 Antibodies 2 Antibodies
Flow Cytometry (FACS) 17 Antibodies 17 Antibodies
Immunochromatography (IC) 1 Antibodies
Immunocytochemistry (ICC) 19 Antibodies 19 Antibodies
Immunofluorescence (IF) 25 Antibodies 24 Antibodies
Immunofluorescence (fixed cells) (IF/ICC) 1 Antibodies 1 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 13 Antibodies
Immunohistochemistry (IHC) 30 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 21 Antibodies
Immunoprecipitation (IP) 9 Antibodies
Western Blotting (WB) 53 Antibodies

General

Antigen Sirtuin 1 (SIRT1) Antibodies
Epitope AA 192-242
(29), (24), (21), (18), (16), (15), (14), (14), (10), (6), (6), (5), (4), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(306), (137), (70), (21), (14), (11), (8), (7), (7), (7), (5), (4), (4), (3), (2), (2), (2), (1)
Host Rabbit
(206), (86), (27), (6), (3)
Clonality
Polyclonal
Conjugate This SIRT1 antibody is un-conjugated
(17), (14), (10), (7), (7), (6), (4), (4), (4), (4), (4), (4), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (1)
Application Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(255), (132), (87), (66), (60), (51), (42), (39), (36), (7), (6), (5), (4), (2), (2), (2), (2), (1), (1)
Pubmed 3 references available
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Product Details anti-SIRT1 Antibody

Target Details SIRT1 Application Details Handling ProductDetails: References for anti-SIRT1 antibody (ABIN729853) Images
Purification Purified by Protein A.
Immunogen KLH conjugated synthetic peptide derived from human SIRT1
Isotype IgG

Target Details SIRT1

Product Details anti-SIRT1 Antibody Application Details Handling ProductDetails: References for anti-SIRT1 antibody (ABIN729853) Images back to top
Antigen
Alternative Name SIRT1 (SIRT1 Antibody Abstract)
Background

This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined, however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2008]

Subcellular location: Cytoplasm, Nucleus

Synonyms: SIR2L1, NAD-dependent protein deacetylase sirtuin-1, hSIRT1, Regulatory protein SIR2 homolog 1, SIR2-like protein 1, hSIR2, SIRT1

Gene ID 23411
UniProt Q96EB6
Research Area Chromatin and Nuclear Signaling, Apoptosis/Necrosis, Proteases
Pathways MAPK Signaling, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Carbohydrate Homeostasis, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus, Negative Regulation of intrinsic apoptotic Signaling

Application Details

Product Details anti-SIRT1 Antibody Target Details SIRT1 Handling ProductDetails: References for anti-SIRT1 antibody (ABIN729853) Images back to top
Application Notes WB 1:100-1000
IHC-P 1:100-500
IF(IHC-P) 1:50-200
Restrictions For Research Use only

Handling

Product Details anti-SIRT1 Antibody Target Details SIRT1 Application Details ProductDetails: References for anti-SIRT1 antibody (ABIN729853) Images back to top
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C
Expiry Date 12 months

ProductDetails: References for anti-SIRT1 antibody (ABIN729853)

Product Details anti-SIRT1 Antibody Target Details SIRT1 Application Details Handling Images back to top
Product cited in:

Yan, Jin, Cao, Wang, Lu, Yang, Wu, Cai: "Effects of Aluminium on Long-Term Memory in Rats and on SIRT1 Mediating the Transcription of CREB-Dependent Gene in Hippocampus." in: Basic & clinical pharmacology & toxicology, Vol. 121, Issue 4, pp. 342-352, 2017 Method employed by authors: Western Blotting (WB) (Sample species: Rat (Rattus)).

Hu, Fan, Lv, Zhou, Yang, Zheng, Cao: "5-Aminolevulinic acid-mediated sonodynamic therapy induces anti-tumor effects in malignant melanoma via p53-miR-34a-Sirt1 axis." in: Journal of dermatological science, Vol. 79, Issue 2, pp. 155-62, 2015 Method employed by authors: Western Blotting (WB) (Sample species: Mouse (Murine)).

Mohan, Kumar, Lackner, Alvarez: "Dysregulated miR-34a-SIRT1-acetyl p65 axis is a potential mediator of immune activation in the colon during chronic simian immunodeficiency virus infection of rhesus macaques." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 194, Issue 1, pp. 291-306, 2014

Images

Product Details anti-SIRT1 Antibody Target Details SIRT1 Application Details Handling ProductDetails: References for anti-SIRT1 antibody (ABIN729853) back to top
Supplier Images
SDS-PAGE (SDS) image for anti-SIRT1 antibody (Sirtuin 1) (AA 192-242) (ABIN729853) Lane 1: mouse liver lysates Lane 2: mouse brain lysates probed with Anti SIRT1 Polycl...
Immunohistochemistry (IHC) image for anti-SIRT1 antibody (Sirtuin 1) (AA 192-242) (ABIN729853) Formalin-fixed and paraffin embedded human endometrial carcinoma labeled with Anti-SI...
Immunohistochemistry (IHC) image for anti-SIRT1 antibody (Sirtuin 1) (AA 192-242) (ABIN729853) Formalin-fixed and paraffin embedded human gastric carcinoma labeled with Anti-SIRT1 ...
Western Blotting (WB) image for anti-SIRT1 antibody (Sirtuin 1) (AA 192-242) (ABIN729853) Protein: mouse heart lysate;
Primary: rabbit Anti-SIRT1 at 1: 5000;
Predic...
Western Blotting (WB) image for anti-SIRT1 antibody (Sirtuin 1) (AA 192-242) (ABIN729853) Hela cell lysates probed with Anti-SIRT1 Polyclonal Antibody, Unconjugated at 1:3000...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-SIRT1 antibody (Sirtuin 1) (AA 192-242) (ABIN729853) Formalin-fixed and paraffin embedded human gastric carcinoma labeled with Anti-SIRT1 ...