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anti-Rat (Rattus) SIRT1 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended SIRT1 Antibody (supplied by: Log in to see )

Antigen
Sirtuin 1 (SIRT1) Antibodies
  • AA673258
  • SIR2
  • Sir2
  • Sir2a
  • Sir2alpha
  • SIR2L1
  • sir2l1
  • sirtuin
  • sirtuin 1
Epitope
AA 192-242
21
20
19
17
16
13
12
10
5
5
4
3
3
3
3
3
3
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
216
98
42
8
6
4
2
1
1
1
1
Host
Rabbit
150
54
25
6
2
Clonality
Polyclonal
Conjugate
This SIRT1 antibody is un-conjugated
12
11
7
3
3
3
3
3
3
3
3
3
3
3
3
1
1
1
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
176
109
43
33
32
31
25
18
9
5
4
4
2
1
1
Supplier
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Catalog No. ABIN729853
$ 269.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0009015372 ABIN729855 IHC (p) WB Biotin Rabbit IgG AA 192-242 Log in to see Polyclonal
0.0009015372 ABIN729862 IHC (p) WB HRP Rabbit IgG AA 192-242 Log in to see Polyclonal
0.0009015372 ABIN1860560 ICC IHC (fro) IHC (p) ELISA WB Rabbit IgG AA 238-482 Log in to see Polyclonal

Top referenced anti-SIRT1 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Similar anti-SIRT1 Antibodies

Application / Reactivity Rat (Rattus) Mouse (Murine)
Chromatin Immunoprecipitation (ChIP) 3 Antibodies
ELISA 15 Antibodies 38 Antibodies
Enzyme Immunoassay (EIA) 1 Antibodies 2 Antibodies
Immunocytochemistry (ICC) 2 Antibodies 2 Antibodies
Immunofluorescence (IF) 8 Antibodies 7 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 11 Antibodies 33 Antibodies
Immunohistochemistry (IHC) 6 Antibodies 13 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 1 Antibodies 2 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 4 Antibodies 12 Antibodies
Immunoprecipitation (IP) 5 Antibodies
Western Blotting (WB) 30 Antibodies

General

Antigen Sirtuin 1 (SIRT1) Antibodies
Epitope AA 192-242
(21), (20), (19), (17), (16), (13), (12), (10), (5), (5), (4), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(216), (98), (42), (8), (6), (4), (2), (1), (1), (1), (1)
Host Rabbit
(150), (54), (25), (6), (2)
Clonality
Polyclonal
Conjugate This SIRT1 antibody is un-conjugated
(12), (11), (7), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (1), (1), (1)
Application Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(176), (109), (43), (33), (32), (31), (25), (18), (9), (5), (4), (4), (2), (1), (1)
Pubmed 1 reference available
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Product Details anti-SIRT1 Antibody

Target Details SIRT1 Application Details Handling References for anti-SIRT1 Antibody (ABIN729853) Images
Purification Purified by Protein A.
Immunogen KLH conjugated synthetic peptide derived from human SIRT1
Isotype IgG

Target Details SIRT1

Product Details anti-SIRT1 Antibody Application Details Handling References for anti-SIRT1 Antibody (ABIN729853) Images back to top
Antigen
Alternative Name SIRT1 (SIRT1 Antibody Abstract)
Background

This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined, however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2008]

Subcellular location: Cytoplasm, Nucleus


Synonyms: SIR2L1, NAD-dependent protein deacetylase sirtuin-1, hSIRT1, Regulatory protein SIR2 homolog 1, SIR2-like protein 1, hSIR2, SIRT1
Gene ID 23411
UniProt Q96EB6
Research Area Chromatin and Nuclear Signaling, Apoptosis/Necrosis, Proteases
Pathways MAPK Signaling

Application Details

Product Details anti-SIRT1 Antibody Target Details SIRT1 Handling References for anti-SIRT1 Antibody (ABIN729853) Images back to top
Application Notes WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
Restrictions For Research Use only

Handling

Product Details anti-SIRT1 Antibody Target Details SIRT1 Application Details References for anti-SIRT1 Antibody (ABIN729853) Images back to top
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 100 μg/mL BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C
Expiry Date 12 months

References for anti-SIRT1 Antibody (ABIN729853)

Product Details anti-SIRT1 Antibody Target Details SIRT1 Application Details Handling Images back to top
Product cited in:

Mohan, Kumar, Lackner, Alvarez: "Dysregulated miR-34a-SIRT1-acetyl p65 axis is a potential mediator of immune activation in the colon during chronic simian immunodeficiency virus infection of rhesus macaques." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 194, Issue 1, pp. 291-306, 2014

Images

Product Details anti-SIRT1 Antibody Target Details SIRT1 Application Details Handling References for anti-SIRT1 Antibody (ABIN729853) back to top
Supplier Images
SDS-PAGE (SDS) image for anti-SIRT1 antibody (Sirtuin 1) (AA 192-242) (ABIN729853) Lane 1: mouse liver lysates Lane 2: mouse brain lysates probed with Anti SIRT1 Polycl...
Immunohistochemistry (IHC) image for anti-SIRT1 antibody (Sirtuin 1) (AA 192-242) (ABIN729853) Formalin-fixed and paraffin embedded human endometrial carcinoma labeled with Anti-SI...
Immunohistochemistry (IHC) image for anti-SIRT1 antibody (Sirtuin 1) (AA 192-242) (ABIN729853) Formalin-fixed and paraffin embedded human gastric carcinoma labeled with Anti-SIRT1 ...
Western Blotting (WB) image for anti-SIRT1 antibody (Sirtuin 1) (AA 192-242) (ABIN729853) Protein: mouse heart lysate;
Primary: rabbit Anti-SIRT1 at 1: 5000;
Predic...
Western Blotting (WB) image for anti-SIRT1 antibody (Sirtuin 1) (AA 192-242) (ABIN729853) Hela cell lysates probed with Anti-SIRT1 Polyclonal Antibody, Unconjugated at 1:3000...