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anti-Xenopus laevis SIRT1 antibody for Western Blotting

Recommended SIRT1 Antibody (supplied by: Log in to see )

Antigen
Sirtuin 1 (SIRT1) Antibodies
  • sirtuin 1
  • AA673258
  • SIR2L1
  • Sir2
  • Sir2a
  • Sir2alpha
  • sir2l1
  • sirtuin
  • SIR2
  • sirtuin 1
  • SIRT1
  • SRT1
  • LOC100349271
  • Sirt1
  • sirt1
Epitope
N-Term
30
23
22
17
16
16
15
15
10
5
4
3
3
3
3
3
3
3
3
3
2
2
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Chicken, Dog (Canine), Human, Mouse (Murine), Pig (Porcine), Rat (Rattus), Xenopus laevis
286
130
65
21
9
7
5
3
3
3
2
2
2
2
1
Host
Rabbit
191
80
27
7
3
Clonality
Polyclonal
Conjugate
This SIRT1 antibody is un-conjugated
15
13
10
6
6
5
4
4
4
3
3
3
3
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
1
Application
Western Blotting (WB)
233
127
78
63
58
48
40
30
30
5
4
4
2
2
2
1
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Catalog No. ABIN2779607
$ 289.00
Plus shipping costs $45.00

Top referenced anti-SIRT1 antibody for Western Blotting

Similar anti-SIRT1 Antibodies

Application / Reactivity Human Chicken Dog (Canine) Mouse (Murine) Pig (Porcine) Rat (Rattus) Xenopus laevis
Simple Western (SimWes) 4 Antibodies 2 Antibodies 2 Antibodies 2 Antibodies 2 Antibodies
Western Blotting (WB) 220 Antibodies 6 Antibodies 8 Antibodies 84 Antibodies 4 Antibodies 47 Antibodies 1 Antibodies
Proximity Ligation Assay (PLA) 2 Antibodies
Immunoprecipitation (IP) 30 Antibodies 3 Antibodies 6 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 57 Antibodies 28 Antibodies 20 Antibodies
Immunohistochemistry (IHC) 75 Antibodies

General

Antigen Sirtuin 1 (SIRT1) Antibodies
Epitope N-Term
(30), (23), (22), (17), (16), (16), (15), (15), (10), (5), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Chicken, Dog (Canine), Human, Mouse (Murine), Pig (Porcine), Rat (Rattus), Xenopus laevis
(286), (130), (65), (21), (9), (7), (5), (3), (3), (3), (2), (2), (2), (2), (1)
Host Rabbit
(191), (80), (27), (7), (3)
Clonality
Polyclonal
Conjugate This SIRT1 antibody is un-conjugated
(15), (13), (10), (6), (6), (5), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (1)
Application Western Blotting (WB)
(233), (127), (78), (63), (58), (48), (40), (30), (30), (5), (4), (4), (2), (2), (2), (1)
Pubmed 4 references available
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Product Details anti-SIRT1 Antibody

Target Details SIRT1 Application Details Handling References for anti-SIRT1 Antibody (ABIN2779607) Images
Blocking Peptide Blocking peptide for this product available: ABIN983762
Sequence PETIPPPELD DMTLWQIVIN ILSEPPKRKK RKDINTIEDA VKLLQECKKI
Predicted Reactivity Bovine : 100 %, Dog : 100 %, Guinea pig : 100 %, Horse : 100 %, Human : 100 %, Mouse : 100 %, Pig : 100 %, Rabbit : 100 %, Rat : 100 %, African clawed frog : 90 %, Chicken : 80 %, Zebrafish : 80 %
Characteristics This is a rabbit polyclonal antibody against SIRT1. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human SIRT1

Target Details SIRT1

Product Details anti-SIRT1 Antibody Application Details Handling References for anti-SIRT1 Antibody (ABIN2779607) Images back to top
Antigen
Alternative Name SIRT1 (SIRT1 Antibody Abstract)
Background SIRT1 is a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined,
Molecular Weight 82 kDa
Gene ID 23411
NCBI Accession NM_012238, NP_036370
UniProt Q96EB6
Research Area Chromatin and Nuclear Signaling, Apoptosis/Necrosis, Proteases
Pathways MAPK Signaling, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling

Application Details

Product Details anti-SIRT1 Antibody Target Details SIRT1 Handling References for anti-SIRT1 Antibody (ABIN2779607) Images back to top
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 747 AA

Restrictions For Research Use only

Handling

Product Details anti-SIRT1 Antibody Target Details SIRT1 Application Details References for anti-SIRT1 Antibody (ABIN2779607) Images back to top
Format Liquid
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage 4 °C,-20 °C
Storage Comment For short term use, store at 2-8 °C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

References for anti-SIRT1 Antibody (ABIN2779607)

Product Details anti-SIRT1 Antibody Target Details SIRT1 Application Details Handling Images back to top
Product cited in:

Cueno, Imai, Tamura, Ochiai: "Butyric acid-induced rat jugular blood cytosolic oxidative stress is associated with SIRT1 decrease." in: Cell stress & chaperones, Vol. 19, Issue 2, pp. 295-8, 2014

Hsu, Chuang: "Changes in energy-regulated molecules in the trophocytes and fat cells of young and old worker honeybees (Apis mellifera)." in: The journals of gerontology. Series A, Biological sciences and medical sciences, Vol. 69, Issue 8, pp. 955-64, 2014

Anavekar, Mirza, Skali, Plappert, St John Sutton, Pfeffer, Solomon,: "Risk assessment in patients with depressed left ventricular function after myocardial infarction using the myocardial performance index--Survival and Ventricular Enlargement (SAVE) experience." in: Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography, Vol. 19, Issue 1, pp. 28-33, 2006

Background publications

Solomon, Pasupuleti, Xu, McDonagh, Curtis, DiStefano, Huber: "Inhibition of SIRT1 catalytic activity increases p53 acetylation but does not alter cell survival following DNA damage." in: Molecular and cellular biology, Vol. 26, Issue 1, pp. 28-38, 2005

Images

Product Details anti-SIRT1 Antibody Target Details SIRT1 Application Details Handling References for anti-SIRT1 Antibody (ABIN2779607) back to top
Supplier Images
Western Blotting (WB) image for anti-SIRT1 antibody (Sirtuin 1) (N-Term) (ABIN2779607) anti-Sirtuin 1 (SIRT1) (N-Term) antibody