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Browse our Stathmin 1 Proteins (STMN1)

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Stathmin 1 Proteins (STMN1)
On www.antibodies-online.com are 28 Stathmin 1 (STMN1) Proteins from 15 different suppliers available. Additionally we are shipping Stathmin 1 Antibodies (354) and Stathmin 1 Kits (47) and many more products for this protein. A total of 449 Stathmin 1 products are currently listed.
Synonyms:
19k, C1orf215, cb959, fj43c10, Lag, Lap18, LOC100217988, Op18, P18, P19, Pig, Pp17, Pp18, Pp19, Pr22, prosolin, Smn, stathmin, stmn1, stmn1a, wu:fb14e04, wu:fj38b07, wu:fj43c10, zgc:110159, zgc:136942
list all proteins Gene Name GeneID UniProt
STMN1 3925 P16949
STMN1 16765 P54227
STMN1 29332 P13668

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Stathmin 1 Proteins (STMN1) by Origin

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Top referenced Stathmin 1 Proteins

  1. Human Stathmin 1 Protein expressed in Escherichia coli (E. coli) - ABIN667094 : Maucuer, Doye, Sobel: A single amino acid difference distinguishes the human and the rat sequences of stathmin, a ubiquitous intracellular phosphoprotein associated with cell regulations. in FEBS letters 1990 (PubMed)
    Show all 3 references for ABIN667094

  2. Human Stathmin 1 Protein expressed in Escherichia coli (E. coli) - ABIN2181791 : Redeker, Lachkar, Siavoshian, Charbaut, Rossier, Sobel, Curmi: Probing the native structure of stathmin and its interaction domains with tubulin. Combined use of limited proteolysis, size exclusion chromatography, and mass spectrometry. in The Journal of biological chemistry 2000 (PubMed)

More Proteins for Stathmin 1 Interaction Partners

Human Stathmin 1 (STMN1) interaction partners

  1. After silencing stathmin-1 in gastric cancer cells, the resistance index was reduced.

  2. Results show that the STMN1-E/P/C signature is a reliable prognostic indicator for luminal subtype breast cancer and may predict the therapeutic response to paclitaxel-based treatments, potentially facilitating individualized management.

  3. STMN1 may play an important role in the development and tumor progression of cutaneous squamous cell carcinoma

  4. Studies indicate that phosphorylation of stathmin controls its biological activity by reducing its affinity for tubulin (show TUBB Proteins) and hence preventing microtubule disassembly.

  5. Data suggest that stathmin 1 silencing or paclitaxel treatment, combined with ruxolitinib could be an effective strategy for promoting apoptosis in Janus kinase 2 (JAK2 (show JAK2 Proteins) V617F) cells.

  6. FANCC (show FANCC Proteins) interacts and co-localizes with STMN1 at centrosomes during mitosis. We also showed that FANCC (show FANCC Proteins) is required for STMN1 phosphorylation.

  7. PDAC patients with higher STMN1 expression died sooner than those with lower STMN1 expression.

  8. stathmin-1 may play a key role in regulating trophoblast invasion

  9. These results suggest that SEPTIN2-mediated cytoskeletal rearrangement and STATHMIN-mediated differentiation may contribute to changes in cell morphology and differentiation of H/RS cells with CD99 (show CD99 Proteins) upregulation in Hodgkin lymphoma.

  10. miR (show MLXIP Proteins)-223 regulates STMN1 in malignant pleural mesothelioma, and both are in turn regulated by the JNK (show MAPK8 Proteins) signaling pathway. As such, miR (show MLXIP Proteins)-223 and STMN1 play an important role in regulating MPM cell motility.

Mouse (Murine) Stathmin 1 (STMN1) interaction partners

  1. We identified stathmin as a key molecule aiding in septin (show SEPT6 Proteins)-independent cytokinesis, demonstrated that stathmin supplementation is sufficient to override cytokinesis failure in SEPT7 (show SEPT7 Proteins)-null fibroblasts

  2. Overexpressing stathmin reduces complement receptor 3 (show ITGAM Proteins)-mediated phagocytosis and cellular activation, implicating a pivotal inhibitory role for stathmin in classically activated macrophages.

  3. Stathmin cooperates with p27(kip1 (show CDKN1B Proteins)) to control the early phase of G1 to S phase transition and that this function may be of particular relevance in the context of tumor progression.

  4. The protein profiles during murine embryo implantation were clarified. Stathmin 1 might be a potential regulator of embryo implantation.

  5. Results show an important role for stathmin during adult neurogenesis in the subgranular zone of the mouse hippocampus; propose that stathmin controls the transition from neuronal precursors to early postmitotic neurons

  6. Stathmin mutations disrupt changes in microtubule stability, GluA2 (show GRIA2 Proteins) localization, synaptic plasticity and memory.

  7. Stmn deletion does not prolong the lifespan of spinal muscular atrophy-like mice, suggesting that stathmin dysregulation and microtubule disruption are not a cause but rather a consequence of SMA (show SMN1 Proteins) pathology.

  8. stathmin expression is dispensable for tumor onset, at least in mice, thus making stathmin a virtually exclusive marker of aggressive disease and a promising therapeutic target for advanced cancers.

  9. results demonstrate the mechanism of stathmin-dependent control of MT dynamics, Rho signaling, and permeability

  10. Stathmin phosphorylates the microtubule network during T cell activation, resulting in increased microtubule growth rate dependent on the presence of stathmin.

Stathmin 1 (STMN1) Protein Profile

Protein Summary

This gene belongs to the stathmin family of genes. It encodes a ubiquitous cytosolic phosphoprotein proposed to function as an intracellular relay integrating regulatory signals of the cellular environment. The encoded protein is involved in the regulation of the microtubule filament system by destabilizing microtubules. It prevents assembly and promotes disassembly of microtubules. Multiple transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with Stathmin 1 (STMN1)

  • stathmin 1 (stmn1-a)
  • stathmin 1 (STMN1)
  • stathmin 1 (stmn1)
  • stathmin 1b (stmn1b)
  • stathmin 1a (stmn1a)
  • stathmin 1/oncoprotein 18 (LOC100217988)
  • stathmin 1/oncoprotein 18 (LOC100229194)
  • stathmin (stmn1)
  • stathmin 1 (Stmn1)
  • 19k protein
  • C1orf215 protein
  • cb959 protein
  • fj43c10 protein
  • Lag protein
  • Lap18 protein
  • LOC100217988 protein
  • Op18 protein
  • P18 protein
  • P19 protein
  • Pig protein
  • Pp17 protein
  • Pp18 protein
  • Pp19 protein
  • Pr22 protein
  • prosolin protein
  • Smn protein
  • stathmin protein
  • stmn1 protein
  • stmn1a protein
  • wu:fb14e04 protein
  • wu:fj38b07 protein
  • wu:fj43c10 protein
  • zgc:110159 protein
  • zgc:136942 protein

Protein level used designations for Stathmin 1 Proteins (STMN1)

oncoprotein 18 , stathmin 1 a , stathmin 1/oncoprotein 18 , fj38b07 , stathmin 1/oncoprotein 18b , stathmin 1 , stathmin , leukemia-associated phosphoprotein p18 , metablastin , phosphoprotein 19 , phosphoprotein p19 , prosolin , transmembrane protein C1orf215 , leukemia associated phosphoprotein p18 , leukemia-associated gene protein , leukemia-associated cytosolic phosphoprotein stathmin , stathmin-1

GENE ID SPECIES
380364 Xenopus laevis
456650 Pan troglodytes
493340 Xenopus (Silurana) tropicalis
550548 Danio rerio
678630 Danio rerio
100217988 Taeniopygia guttata
100229194 Taeniopygia guttata
100528882 Ictalurus punctatus
3925 Homo sapiens
16765 Mus musculus
29332 Rattus norvegicus
100732759 Cavia porcellus
396057 Gallus gallus
494463 Sus scrofa
616317 Bos taurus
478175 Canis lupus familiaris
101113917 Ovis aries
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