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Data suggest that newly synthesized protein(s) are required for cAMP induction of Hsd3b4 and CYP17 (show CYP17A1 ELISA Kits) mRNA levels (but not of CYP11A (show CYP11A1 ELISA Kits) mRNA levels). [REVIEW]
The steroid hormone enzyme 3beta-hydroxysteroid dehydrogenase 4 (3betaHSD4) was identified as a novel target of vasopressin (show AVP ELISA Kits) regulation. Its expression is colocalized in AQP2 (show AQP2 ELISA Kits)-expressing collecting ducts of the kidney.
The 3-beta-HSD enzymatic system plays a crucial role in the biosynthesis of all classes of hormonal steroids. HSD IV can only catalyze the conversion of dihydrotestosterone to 5 alpha- androstanediol in the presence of the cofactor NADPH. Does not function as a isomerase.
3 beta-hydroxysteroid dehydrogenase 4
, 3 beta-hydroxysteroid dehydrogenase type 4
, 3 beta-hydroxysteroid dehydrogenase type IV
, 3-beta-HSD IV
, 3-beta-hydroxy-5-ene steroid dehydrogenase
, 3-beta-hydroxysteroid dehydrogenase/delta-5-delta-4 isomerase
, NADPH-dependent 3-beta-hydroxy-Delta(5)-steroid dehydrogenase
, hydroxysteroid dehydrogenase-4, delta<5>-3-beta
, progesterone reductase