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Browse our anti-Steroid-5-alpha-Reductase, alpha Polypeptide 2 (3-Oxo-5 alpha-Steroid delta 4-Dehydrogenase alpha 2) (SRD5A2) Antibodies

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anti-Steroid-5-alpha-Reductase, alpha Polypeptide 2 (3-Oxo-5 alpha-Steroid delta 4-Dehydrogenase alpha 2) Antibodies (SRD5A2)
On www.antibodies-online.com are 72 Steroid-5-alpha-Reductase, alpha Polypeptide 2 (3-Oxo-5 alpha-Steroid delta 4-Dehydrogenase alpha 2) (SRD5A2) Antibodies from 11 different suppliers available. Additionally we are shipping Steroid-5-alpha-Reductase, alpha Polypeptide 2 (3-Oxo-5 alpha-Steroid delta 4-Dehydrogenase alpha 2) Kits (21) and Steroid-5-alpha-Reductase, alpha Polypeptide 2 (3-Oxo-5 alpha-Steroid delta 4-Dehydrogenase alpha 2) Proteins (4) and many more products for this protein. A total of 103 Steroid-5-alpha-Reductase, alpha Polypeptide 2 (3-Oxo-5 alpha-Steroid delta 4-Dehydrogenase alpha 2) products are currently listed.
Synonyms:
5ART2, S5AR 2, Srd5a2, SRD5alpha2
list all antibodies Gene Name GeneID UniProt
SRD5A2 94224 Q99N99
SRD5A2 6716 P31213
SRD5A2 64677 P31214

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Most Popular Reactivities for anti-Steroid-5-alpha-Reductase, alpha Polypeptide 2 (3-Oxo-5 alpha-Steroid delta 4-Dehydrogenase alpha 2) (SRD5A2) Antibodies

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All available anti-Steroid-5-alpha-Reductase, alpha Polypeptide 2 (3-Oxo-5 alpha-Steroid delta 4-Dehydrogenase alpha 2) Antibodies

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Top referenced anti-Steroid-5-alpha-Reductase, alpha Polypeptide 2 (3-Oxo-5 alpha-Steroid delta 4-Dehydrogenase alpha 2) Antibodies

  1. Human Polyclonal SRD5A2 Primary Antibody for ELISA - ABIN268809 : Iczkowski, Qiu, Qian, Somerville, Rittmaster, Andriole, Bostwick: The dual 5-alpha-reductase inhibitor dutasteride induces atrophic changes and decreases relative cancer volume in human prostate. in Urology 2005 (PubMed)

  2. Human Monoclonal SRD5A2 Primary Antibody for ELISA, WB - ABIN520465 : Sato, Iemitsu, Matsutani, Kurihara, Hamaoka, Fujita: Resistance training restores muscle sex steroid hormone steroidogenesis in older men. in FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2014 (PubMed)

  3. Human Polyclonal SRD5A2 Primary Antibody for ELISA, WB - ABIN562991 : Park, Aizawa, Iemitsu, Sato, Akimoto, Agata, Maeda, Ezawa, Omi: DHEA administration activates local bioactive androgen metabolism in cancellous site of tibia of ovariectomized rats. in Calcified tissue international 2011 (PubMed)

  4. Human Polyclonal SRD5A2 Primary Antibody for IHC, WB - ABIN2781788 : Bertin, Dury, Ouellet, Pelletier, Labrie: Localization of the Androgen-Synthesizing Enzymes, Androgen Receptor, and Sex Steroids in the Vagina: Possible Implications for the Treatment of Postmenopausal Sexual Dysfunction. in The journal of sexual medicine 2014 (PubMed)

  5. Human Polyclonal SRD5A2 Primary Antibody for ELISA, WB - ABIN451821 : Torkko, van Bokhoven, Mai, Beuten, Balic, Byers, Hokanson, Norris, Barón, Lucia, Thompson, Leach: VDR and SRD5A2 polymorphisms combine to increase risk for prostate cancer in both non-Hispanic White and Hispanic White men. in Clinical cancer research : an official journal of the American Association for Cancer Research 2008 (PubMed)

  6. Human Polyclonal SRD5A2 Primary Antibody for WB - ABIN374517 : Vu, Hirst, Stark, Wright, Palliser, Hodyl, Clifton: Changes in human placental 5alpha-reductase isoenzyme expression with advancing gestation: effects of fetal sex and glucocorticoid exposure. in Reproduction, fertility, and development 2009 (PubMed)

More Antibodies against Steroid-5-alpha-Reductase, alpha Polypeptide 2 (3-Oxo-5 alpha-Steroid delta 4-Dehydrogenase alpha 2) Interaction Partners

Mouse (Murine) Steroid-5-alpha-Reductase, alpha Polypeptide 2 (3-Oxo-5 alpha-Steroid delta 4-Dehydrogenase alpha 2) (SRD5A2) interaction partners

  1. observed an abnormally high expression levels of type 2 5alpha-reductase and 20alpha-HSD in the male and female adrenals, respectively, thus indirectly suggesting new roles for these sex-specific enzymes

  2. The induction of Srd5a2 through SREBP-2 (show SREBF2 Antibodies) provides a mechanistic explanation for why even though statin therapy is effective in reducing cholesterol levels in treating hypercholesterolemia it does not compromise androgen production in clinical studies.

Human Steroid-5-alpha-Reductase, alpha Polypeptide 2 (3-Oxo-5 alpha-Steroid delta 4-Dehydrogenase alpha 2) (SRD5A2) interaction partners

  1. p.Ala65Pro mutation in the SRD5A2 gene causes 5alphaRD2 deficiency, especially in Turkey. V89L polymorphism may also be an important factor in the development of external genitalia

  2. deletion of exon 2 in the SRD5A2 gene causes various degrees of genital ambiguity leading to different sex of rearing in affected family members

  3. Mutations in SRD5A2 gene were found in 46, XY DSD (show FADS1 Antibodies) children with pediatric hypospadias.

  4. Diagnosis of 5alpha-reductase 2 deficiency with assessment of the SRD5A2 gene may help in appropriate gender assignment.

  5. Results suggest that SRD5A2 controls cell migration by indirectly regulating ERK/MAPK (show MAPK1 Antibodies) pathway in prostate cancer cells.

  6. Metabolic syndrome develops more frequently in testicular cancer survivors homozygous or heterozygous variant for SNP rs523349 in SRD5A2.

  7. the V89L and TA repeat polymorphisms of SRD5A2 gene were found to have no significant associations with breast cancer

  8. the genotypic distribution of 22 single nucleotide polymorphisms in SRD5A1 (show SRD5A1 Antibodies) and SRD5A2 in a set of Spanish prostate cancer patients, were evaluated.

  9. In prostate cancer, increased DNA methylation (show HELLS Antibodies) of SRD5A2 and CYP11A1 (show CYP11A1 Antibodies) related to androgen biosynthesis functions may play a role in biochemical recurrence after patients' prostatectomy

  10. SRD5A2 gene polymorphisms are associated with the risk of benign prostatic hyperplasia but not prostate cancer.

Steroid-5-alpha-Reductase, alpha Polypeptide 2 (3-Oxo-5 alpha-Steroid delta 4-Dehydrogenase alpha 2) (SRD5A2) Antigen Profile

Antigen Summary

This gene encodes a microsomal protein expressed at high levels in androgen-sensitive tissues such as the prostate. The encoded protein is active at acidic pH and is sensitive to the 4-azasteroid inhibitor finasteride. Deficiencies in this gene can result in male pseudohermaphroditism, specifically pseudovaginal perineoscrotal hypospadias (PPSH).

Alternative names and synonyms associated with Steroid-5-alpha-Reductase, alpha Polypeptide 2 (3-Oxo-5 alpha-Steroid delta 4-Dehydrogenase alpha 2) (SRD5A2)

  • steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2) (SRD5A2) antibody
  • steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2) (srd5a2) antibody
  • steroid-5-alpha-reductase alpha polypeptide 2 (srd5a2) antibody
  • steroid 5 alpha-reductase 2 (Srd5a2) antibody
  • steroid 5-alpha-reductase 2 (ST5AR2) antibody
  • steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2) (Srd5a2) antibody
  • 5ART2 antibody
  • S5AR 2 antibody
  • Srd5a2 antibody
  • SRD5alpha2 antibody

Protein level used designations for SRD5A2

3-oxo-5-alpha-steroid 4-dehydrogenase 2 , steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2) , steroid-5-alpha-reductase alpha polypeptide 2 , 5 alpha-SR2 , SR type 2 , steroid 5 alpha reductase type2 , steroid 5-alpha-reductase 2 , S5AR 2 , type II 5-alpha reductase , prostatic steroid 5-alpha-reductase type II

GENE ID SPECIES
527024 Bos taurus
772291 Gallus gallus
549867 Xenopus (Silurana) tropicalis
705676 Macaca mulatta
100125532 Oryzias latipes
94224 Mus musculus
397048 Sus scrofa
6716 Homo sapiens
64677 Rattus norvegicus
403715 Canis lupus familiaris
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