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Browse our Steroid 5 alpha-Reductase 3 (SRD5A3) ELISA Kits

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Steroid 5 alpha-Reductase 3 ELISA Kits (SRD5A3)
On are 0 Steroid 5 alpha-Reductase 3 (SRD5A3) ELISA Kits from different suppliers available. Additionally we are shipping Steroid 5 alpha-Reductase 3 Antibodies (23) and Steroid 5 alpha-Reductase 3 Proteins (3) and many more products for this protein. A total of 29 Steroid 5 alpha-Reductase 3 products are currently listed.
1110025P14Rik, A430076C09, AV364670, AW987574, CDG1P, CDG1Q, D730040M03Rik, H5ar, KRIZI, RGD1308828, S5AR 3, Srd5a2l, SRD5A2L1, SRD5alpha3
list all ELISA KIts Gene Name GeneID UniProt
Human SRD5A3 SRD5A3 79644 Q9H8P0
Mouse SRD5A3 SRD5A3 57357 Q9WUP4
Rat SRD5A3 SRD5A3 305291 Q5RJM1

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More ELISA Kits for Steroid 5 alpha-Reductase 3 Interaction Partners

Human Steroid 5 alpha-Reductase 3 (SRD5A3) interaction partners

  1. Although 4-dione is the main source of 5alpha-dihydrotestosterone in human preadipocytes, production of this steroid by 5 alpha-reductase isoenzymes (SRD5A1 (show SRD5A1 ELISA Kits), 2 and 3) mediates the inhibitory effect of both 4-dione and testosterone on preadipocyte differentiation.

  2. Mutations in the SRD5A3 gene may cause early-onset retinal dystrophy (show MERTK ELISA Kits), a previously underdescribed feature of the SRD5A3-CDG disorder that is progressive and may lead to serious visual impairment.

  3. the spectrum of phenotypes resulting from SRD5A3 mutations and the clinical variability of SRD5A3-CDG

  4. Findings suggest that overexpression of 5alpha-reductase, through a higher inactivation of cortisol in the liver, could have a protective role in preserving hepatic sensitivity to insulin (show INS ELISA Kits).

  5. Next generation sequencing identified a homozygous frameshift mutation (c.203dupC; p.Phe69LeufsX2) SRD5A3 as the disease-causing change in Kahrizi syndrome.

  6. A novel syndrome is identified in families with cerebellar ataxia (show USP14 ELISA Kits) and congenital eye malformations due to steroid 5 alpha-reductase type 3 disorders of glycosylation.

  7. Study of a large consanguineous Emirati family showed that loss of function mutations of the SRD5A3 gene cause a multisystemic syndrome with eye malformations, cerebellar vermis hypoplasia, and psychomotor delay.

  8. Findings indicate that a novel type 3 5 alpha-steroid reductase, SRD5A3, is associated with DHT production and maintenance of androgen-androgen receptor (show AR ELISA Kits)-pathway activation in prostate cancer.

Mouse (Murine) Steroid 5 alpha-Reductase 3 (SRD5A3) interaction partners

  1. Srd5a3 mutation is lethal in mouse and results in an activation of the unfolded protein response pathway.

Steroid 5 alpha-Reductase 3 (SRD5A3) Antigen Profile

Antigen Summary

The protein encoded by this gene belongs to the steroid 5-alpha reductase family, and polyprenol reductase subfamily. It is involved in the production of androgen 5-alpha-dihydrotestosterone (DHT) from testosterone, and maintenance of the androgen-androgen receptor activation pathway. This protein is also necessary for the conversion of polyprenol into dolichol, which is required for the synthesis of dolichol-linked monosaccharides and the oligosaccharide precursor used for N-linked glycosylation of proteins. Mutations in this gene are associated with congenital disorder of glycosylation type Iq.

Alternative names and synonyms associated with Steroid 5 alpha-Reductase 3 (SRD5A3)

  • steroid 5 alpha-reductase 3 (SRD5A3) Elisa Kit
  • steroid 5 alpha-reductase 3 (Srd5a3) Elisa Kit
  • steroid 5 alpha-reductase 3 (srd5a3) Elisa Kit
  • 1110025P14Rik Elisa Kit
  • A430076C09 Elisa Kit
  • AV364670 Elisa Kit
  • AW987574 Elisa Kit
  • CDG1P Elisa Kit
  • CDG1Q Elisa Kit
  • D730040M03Rik Elisa Kit
  • H5ar Elisa Kit
  • KRIZI Elisa Kit
  • RGD1308828 Elisa Kit
  • S5AR 3 Elisa Kit
  • Srd5a2l Elisa Kit
  • SRD5A2L1 Elisa Kit
  • SRD5alpha3 Elisa Kit

Protein level used designations for SRD5A3

3-oxo-5-alpha-steroid 4-dehydrogenase 3 , S5AR 3 , SR type 3 , polyprenol reductase , probable polyprenol reductase , H5AR , steroid 5 alpha-reductase 2 like , steroid 5 alpha-reductase 2-like; H5AR gene; steroid 5 alpha-reductase 2 like , steroid 5-alpha-reductase 3 , Probable polyprenol reductase , Steroid 5-alpha-reductase 3

79644 Homo sapiens
482155 Canis lupus familiaris
535834 Bos taurus
57357 Mus musculus
305291 Rattus norvegicus
379123 Xenopus laevis
100463734 Ailuropoda melanoleuca
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