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|Antigen||CAP-GLY Domain Containing Linker Protein 2 (CLIP2) Antibodies|
|Reactivity||Human, Mouse (Murine), Rat (Rattus) Alternatives|
|Conjugate||This CLIP2 antibody is conjugated to Alexa Fluor 488 Alternatives|
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
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Product Details anti-CLIP2 AntibodyTarget Details CLIP2 Application Details Handling Images
|Purification||Purified by Protein A.|
|Immunogen||KLH conjugated synthetic peptide derived from human CYLN2|
Target Details CLIP2Product Details anti-CLIP2 Antibody Application Details Handling Images back to top
|Alternative Name||Cyln2/Clip (CLIP2 Antibody Abstract)|
Williams Syndrome (WS) is a developmental disorder characterized by cardiovascular problems, dysmorphic features, mental retardation or learning difficulties and several typical behavioral and neurological abnormalities. In Williams Syndrome patients, a heterozygous deletion is present in a region on chromosome 7q11.23 (the Williams Syndrome critical region), which spans approximately 20 genes. This region comprises the CYLN2 gene, which encodes the cytoplasmic linker protein of (CLIP-115). CLIP-115 is a microtubule-binding protein that is abundantly expressed in the brain. Mice with haploinsufficiency for the CYLN2 gene have features similar to that of WS, including mild growth deficiency, brain abnormalities, hippocampal dysfunction and particular deficits in motor coordination.
Synonyms: CAP GLY domain containing linker protein 2, CAP-Gly domain-containing linker protein 2, CLIP 115, CLIP, CLIP-115, CLIP2, CLIP2_HUMAN, cytoplasmic linker 2, Cytoplasmic linker protein 115, Cytoplasmic linker protein 2, KIAA0291, MGC11333, restin, Similar to RESTIN CYTOPLASMIC LINKER PROTEIN 170 ALPHA 2, WBSCR3, WBSCR4, Williams Beuren syndrome chromosome region 3, Williams Beuren syndrome chromosome region 4, Williams-Beuren syndrome chromosomal region 3 protein, Williams-Beuren syndrome chromosomal region 4 protein, WSCR3, WSCR4.
Application DetailsProduct Details anti-CLIP2 Antibody Target Details CLIP2 Handling Images back to top
|Application Notes||IF(IHC-P) 1:50-200|
|Restrictions||For Research Use only|
HandlingProduct Details anti-CLIP2 Antibody Target Details CLIP2 Application Details Images back to top
|Buffer||Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.|
|Precaution of Use||This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.|
|Storage Comment||Store at 4°C|
|Expiry Date||12 months|