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anti-Mouse (Murine) MAP1A Antibodies:
anti-Human MAP1A Antibodies:
anti-Rat (Rattus) MAP1A Antibodies:
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Rat (Rattus) Monoclonal MAP1A Primary Antibody for IHC (fro), IHC (p) - ABIN1108121
Fink, Jones, Esposito, Wilkowski: Human microtubule-associated protein 1a (MAP1A) gene: genomic organization, cDNA sequence, and developmental- and tissue-specific expression. in Genomics 1996
Show all 2 references for ABIN1108121
Independent double-stranded RNA interference lines displaying distinct MAP1A levels demonstrated that the extent of the developmental defect specifically depends on the concentration of MAP1A.
Mutant mice lacking MAP1A exhibited reduced synaptic plasticity.
Although MAP1A and MAP1B (show MAP1B Antibodies) protein levels are not affected in the tulp1 (show TULP1 Antibodies)-/- retina, they are no longer localized to the outer segment of photoreceptors.
The interaction between the conserved COOH-terminal 125-amino acid domain (which is located in the light chains of MAP1A, MAP1B (show MAP1B Antibodies), and MAP1S (show MAP1S Antibodies)) and alpha1-syntrophin (show SNTA1 Antibodies) is direct and occurs through the pleckstrin (show PLEK Antibodies) homology domain 2 (PH2 (show PhC2 Antibodies)).
It was demonstrated that the gene Mtap1a modifies retinal degeneration in Tub(tub/tub (show TUB Antibodies)) and Tulp1 (show TULP1 Antibodies)(tm1Pjn/tm1Pjn) mice.
Data indicate that protective alleles of Mtap1a are not sufficient to rescue DW/J-Pou1f1dw/dw mutant hearing.
Microtubule-associated protein 1A is a modifier of tubby (show TUB Antibodies) hearing (moth1).
Data show that two regulatory factor for X box (RFX1 (show RFX1 Antibodies) and 3) binding sites in exon1 of both the mouse and human microtubule-associated protein (show SPAG5 Antibodies) (MAP1A) gene are important for effective transcriptional repression in non-neuronal cells.
Microtubule-associated protein (show SPAG5 Antibodies) light chain 2 interacts with the intracellular C-terminal tail of stargazin (show CACNG2 Antibodies).
there is a novel interaction between the C-terminal tail of the BKCa (show KCNMA1 Antibodies) channel and the light chain of MAP1A, which enables channel association with and modulation by the cytoskeleton
MAP1A functions to maintain the neuronal microtubule network in the brain and mutations cause Purkinje cell degeneration (show AGTPBP1 Antibodies).
results support a role for MAP1 (show MASP1 Antibodies) proteins in promoting efficient retrograde trafficking of HIV-1 by stimulating the formation of stable microtubules and mediating the association of HIV-1 cores with microtubules.
Data show that two regulatory factor for X box (RFX1 (show RFX1 Antibodies) and 3) binding sites in exon1 of both the mouse and human microtubule-associated protein (MAP1A) gene are important for effective transcriptional repression in non-neuronal cells.
a novel protein-binding partner for EPAC1 (show RAPGEF3 Antibodies) and EPAC2 (show RAPGEF4 Antibodies), light chain 2 of MAP1A (microtubule-associated protein 1A)
MAP1A LC2 is a biological enhancer of EPAC1 activity toward Rap1 and associated downstream signaling mechanisms
Complexes (MAP1B (show MAP1B Antibodies) heavy chain-MAP1A light chain) form through interaction of homologous domains conserved in heavy and light chains of MAP1A and MAP1B (show MAP1B Antibodies). Conserved domains of the MAP1A and MAP1B (show MAP1B Antibodies) light chains account for formation of light chain heterodimers.
postulate that the RhoB and MAP1A/LC2 interactions facilitate endocytic vesicle trafficking and regulate the trafficking of signaling molecules
This gene encodes a protein that belongs to the microtubule-associated protein family. The proteins of this family are thought to be involved in microtubule assembly, which is an essential step in neurogenesis. The product of this gene is a precursor polypeptide that presumably undergoes proteolytic processing to generate the final MAP1A heavy chain and LC2 light chain. Expression of this gene is almost exclusively in the brain. Studies of the rat microtubule-associated protein 1A gene suggested a role in early events of spinal cord development.
, microtubule-associated protein 1A
, methionine aminopeptidase
, modifier of tubby hearing 1
, proliferation-related protein p80