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|Application / Reactivity||Rat (Rattus)||Human||Mouse (Murine)|
|Western Blotting (WB)||15 Antibodies||20 Antibodies||14 Antibodies|
|Microarray (MA)||1 Antibodies||1 Antibodies||1 Antibodies|
|Immunoprecipitation (IP)||4 Antibodies||1 Antibodies|
|Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))||7 Antibodies||7 Antibodies||3 Antibodies|
|Immunohistochemistry (IHC)||6 Antibodies||4 Antibodies||6 Antibodies|
|Immunohistochemistry (Frozen Sections) (IHC (fro))||8 Antibodies||8 Antibodies||7 Antibodies|
|Antigen||Microtubule-Associated Protein 1B (MAP1B) Antibodies|
|Epitope||AA 1745-1858 Alternatives|
|Reactivity||Human, Mouse (Murine), Rat (Rattus) Alternatives|
|Conjugate||This MAP1B antibody is un-conjugated Alternatives|
Western Blotting (WB)
|2 references available|
|Supplier||Log in to see|
Product Details anti-MAP1B AntibodyTarget Details MAP1B Application Details Handling References for anti-MAP1B Antibody (ABIN968910) Images
|Cross-Reactivity||Human, Rat (Rattus)|
1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
|Purification||The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.|
|Immunogen||Mouse MAP1B aa. 1745-1858|
Target Details MAP1BProduct Details anti-MAP1B Antibody Application Details Handling References for anti-MAP1B Antibody (ABIN968910) Images back to top
|Alternative Name||MAP1B (MAP1B Antibody Abstract)|
|Background||Microtubule-associated proteins (MAPs) play a crucial role in the development and structure of nerve cells. These proteins are important for the assembly and stability of microtubles during neurite outgrowth and for the morphology of neuronal processes, such as dendrites. MAP1B encodes for a single precursor protein that is cleaved to produce a single heavy chain of 280 kDa and a light chain of 32 kDa which become noncovalently associated. Expression levels of MAP1B are reportedly highest in the brain and are modulated during development as reported with gene silencing experiments that implicate MAP1B's role during neuronal differentiation. In addition, MAP1B can be selectively phosphorylated depending on the cell type, subcellular localization and developmental phase. In neurons, MAP1B is expressed as a glycoprotein at the plasma membrane, where it can interact with proteins participating in axonal guiding. MAP1B has been reported to be observable to migrate in a range between 320-340 kDa. This antibody is routinely tested by western blot analysis.|
|Molecular Weight||320-340 kDa|
Application DetailsProduct Details anti-MAP1B Antibody Target Details MAP1B Handling References for anti-MAP1B Antibody (ABIN968910) Images back to top
Related Products: ABIN967389
|Restrictions||For Research Use only|
HandlingProduct Details anti-MAP1B Antibody Target Details MAP1B Application Details References for anti-MAP1B Antibody (ABIN968910) Images back to top
|Buffer||Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.|
|Precaution of Use||This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Storage Comment||Store undiluted at -20° C.|
References for anti-MAP1B Antibody (ABIN968910)Product Details anti-MAP1B Antibody Target Details MAP1B Application Details Handling Images back to top
|Product cited in:||
Ma, Himes, Shea et al.: "Axonal transport of microtubule-associated protein 1B (MAP1B) in the sciatic nerve of adult rat: distinct transport rates of different isoforms." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 20, Issue 6, pp. 2112-20, 2000 (PubMed).
Tögel, Wiche, Propst: "Novel features of the light chain of microtubule-associated protein MAP1B: microtubule stabilization, self interaction, actin filament binding, and regulation by the heavy chain." in: The Journal of cell biology, Vol. 143, Issue 3, pp. 695-707, 1998 (PubMed).
ImagesProduct Details anti-MAP1B Antibody Target Details MAP1B Application Details Handling References for anti-MAP1B Antibody (ABIN968910) back to top